Výsledky vyhledávání - "Dawn Torgersen"

Localization of the Serine Protease-binding Sites in the Collagen-like Domain of Mannose-binding Protein

Autor: Ce-Belle Chen, Jonathan M. Shaw, Russell Wallis, Joost C.M. Uitdehaag, Kurt Drickamer, Dawn Torgersen

Publikováno v: Journal of Biological Chemistry. 279:14065-14073

Mutations in the collagen-like domain of serum mannose-binding protein (MBP) interfere with the ability of the protein to initiate complement fixation through the MBP-associated serine proteases (MASPs). The resulting deficiency in the innate immune

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31cd868449f90b5fce1faf6ace31988d
https://doi.org/10.1074/jbc.m400171200

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Mechanism of pH-dependentN-Acetylgalactosamine Binding by a Functional Mimic of the Hepatocyte Asialoglycoprotein Receptor

Autor: Hadar Feinberg, William I. Weis, Dawn Torgersen, Kurt Drickamer

Publikováno v: Journal of Biological Chemistry. 275:35176-35184

Efficient release of ligands from the Ca(2+)-dependent carbohydrate-recognition domain (CRD) of the hepatic asialoglycoprotein receptor at endosomal pH requires a small set of conserved amino acids that includes a critical histidine residue. When the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f4ec3e4ddb2b9f96c075a8a55ff070
https://doi.org/10.1074/jbc.m005557200

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Mechanism of Ligand Binding to E- and P-selectin Analyzed Using Selectin/Mannose-binding Protein Chimeras

Autor: Kurt Drickamer, Nicholas P. Mullin, Dawn Torgersen

Publikováno v: Journal of Biological Chemistry. 273:6254-6261

The mechanism of oligosaccharide binding to the selectin cell adhesion molecules has been analyzed by transferring regions of the carbohydrate-recognition domains of E- and P-selectin into corresponding sites in the homologous rat serum mannose-bindi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5693a951b3318b0253e88b45aacd134
https://doi.org/10.1074/jbc.273.11.6254

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Localization of the serine protease-binding sites in the collagen-like domain of mannose-binding protein: indirect effects of naturally occurring mutations on protease binding and activation

Autor: Russell, Wallis, Jonathan M, Shaw, Joost, Uitdehaag, Ce-Belle, Chen, Dawn, Torgersen, Kurt, Drickamer

Publikováno v: The Journal of biological chemistry. 279(14)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c5693484d44b14023a14c0667de0ae8
https://pubmed.ncbi.nlm.nih.gov/14724269

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