Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dawn Sijin Nin"'
Autor:
Dawn Sijin Nin, Lih-Wen Deng
Publikováno v:
Cells, Vol 12, Iss 6, p 926 (2023)
Tumour-specific antigens have been an area of interest in cancer therapy since their discovery in the middle of the 20th century. In the era of immune-based cancer therapeutics, redirecting our immune cells to target these tumour-specific antigens ha
Externí odkaz:
https://doaj.org/article/09f9dce492374120a7282a47d87455cc
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1733-1748 (2016)
Post-translational modification can modulate protein conformation and alter binding partner recruitment within gene regulatory regions. Here, we report that bromodomain-containing protein 4 (BRD4), a transcription co-factor and chromatin regulator, u
Externí odkaz:
https://doaj.org/article/3b8b5ad868b341e3a27fe0cc7fc5ccef
Publikováno v:
Frontiers in Oncology, Vol 5 (2015)
Nuclear receptor co-repressor (N-CoR) is the key component of generic co-repressor complex essential for the transcriptional control of genes involved in cellular hemostasis. We have recently reported that N-CoR actively represses Flt3, a key factor
Externí odkaz:
https://doaj.org/article/ceab4a4217004ab7a5c80e80ea1b4cd0
Autor:
Dawn Sijin Nin, Azhar Bin Ali, Koichi Okumura, Norio Asou, Chien-Shing Chen, Wee Joo Chng, Matiullah Khan
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70891 (2013)
The nuclear receptor co-repressor (N-CoR) is a key component of the generic co-repressor complex that plays an important role in the control of cellular growth and differentiation. As shown by us recently, the growth suppressive function of N-CoR lar
Externí odkaz:
https://doaj.org/article/54ff759e7ffb45a09e1e79e5c00e4617
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34501 (2012)
The nuclear receptor co-repressor (N-CoR) is a key component of the generic multi-protein complex involved in transcriptional control. Flt3, a key regulator of hematopoietic cell growth, is frequently deregulated in AML (acute myeloid leukemia). Here
Externí odkaz:
https://doaj.org/article/d81c90eea2784976a5b6117de1ec5ea8
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25268 (2011)
Nuclear receptor co-repressor (N-CoR) plays important role in transcriptional control mediated by several tumor suppressor proteins. Recently, we reported a role of misfolded-conformation dependent loss (MCDL) of N-CoR in the activation of oncogenic
Externí odkaz:
https://doaj.org/article/8f070c97e44e4376b8fbfdfccd95d373
We previously identified a novel MLL5 isoform, MLL5β, which was essential for E6 and E7 transcriptional activation in HPV16/18-associated cervical cancers. In this report, we investigated the potential of RNAi-mediated silencing of MLL5β through th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1144974dd3f617daf3558a3fbc44da93
https://doi.org/10.1158/1535-7163.c.6537139
https://doi.org/10.1158/1535-7163.c.6537139
Supplementary Table 1: Sequences of siRNAs used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcb406ba45496b2548b4a96d14764d8
https://doi.org/10.1158/1535-7163.22502635
https://doi.org/10.1158/1535-7163.22502635
Supplementary Figure S2: Pixel density analysis of E6 and E7 protein expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744ee0cdfc126c8719e51ce3efd5a4e1
https://doi.org/10.1158/1535-7163.22502638
https://doi.org/10.1158/1535-7163.22502638
Supplementary Table 2: Sequences of primers used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a2296370afc2ca2ee30de97136aa89
https://doi.org/10.1158/1535-7163.22502632
https://doi.org/10.1158/1535-7163.22502632