Výsledky vyhledávání - "Dawn Retherford"

Measurement properties of Patient Reported Outcomes Measurement Information System domains for children with type 1 diabetes

Autor: Ashima Singh, Mahua Dasgupta, Rosanna Fiallo-Scharer, Pippa Simpson, Dawn Retherford, Julie A. Panepinto

Publikováno v: Pediatr Diabetes

OBJECTIVE: Patient Reported Outcomes Measurement Information System (PROMIS) includes numerous domains to assess functioning among the pediatric population. These domains, however, have not been evaluated for use in children with type 1 diabetes (T1D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f7eac0b5d623aacaeae2897f8d0ecc
https://doi.org/10.1111/pedi.13134

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Neuropathic pain is associated with poor health‐related quality of life in adolescents with sickle cell disease: A preliminary report

Autor: Amanda M. Brandow, Dawn Retherford, Marisa Roman, Janelle Highland, Julie A. Panepinto, Amy Pan

Publikováno v: Pediatric Blood & Cancer. 67

Background Neuropathic pain is associated with poor health-related quality of life (HRQL) in pain conditions other than sickle cell disease (SCD); this relationship in SCD is unknown. We investigated this relationship and hypothesized neuropathic pai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a210bfaa68fcc6d53b902b1c148d1d8e
https://doi.org/10.1002/pbc.28698

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Characterization of a mouse model of sickle cell trait: parallels to human trait and a novel finding of cutaneous sensitization

Autor: Cheryl A. Hillery, Cheryl L. Stucky, Yihe Guo, Katherine J. Zappia, Dawn Retherford, Nancy J. Wandersee

Publikováno v: British Journal of Haematology. 179:657-666

Sickle cell trait (SCT) has classically been categorized as a benign condition except in rare cases or upon exposure to severe physical conditions. However, several lines of evidence indicate that individuals with SCT are not always asymptomatic, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07931b18afe45bc0f407479c353a252b
https://doi.org/10.1111/bjh.14948

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Neuropathic Pain Is Associated with Poor Health-Related Quality of Life in Adolescents with Sickle Cell Disease

Autor: Dawn Retherford, Marisa Roman, Amanda M. Brandow, Janelle Highland, Amy Pan, Julie A. Panepinto

Publikováno v: Blood. 134:417-417

Background. The hallmark complication of sickle cell disease (SCD) is pain - both acute pain and chronic, daily pain that worsens with increasing age. Emerging data reveal patients with SCD display features of nervous system sensitization, with assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4d01e7805ddcaa0fa581df4630b89f44
https://doi.org/10.1182/blood-2019-127626

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Transient receptor potential vanilloid 1 mediates pain in mice with severe sickle cell disease

Autor: Cheryl A. Hillery, Cheryl L. Stucky, Daniel Vilceanu, Patrick C. Kerstein, Dawn Retherford, Nancy J. Wandersee, Marie E. Barabas, Amanda M. Brandow

Publikováno v: Blood. 118:3376-3383

Pain is the leading cause of emergency department visits, hospitalizations, and daily suffering in individuals with sickle cell disease (SCD). The pathologic mechanisms leading to the perception of pain during acute RBC sickling episodes and developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b50f9ba7fd36a5f727e216922bf2b4
https://doi.org/10.1182/blood-2010-12-327429

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A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia

Autor: Neil Hogg, Sandra L. Holzhauer, Timothy C. Flewelen, Dawn Retherford, Kirkwood A. Pritchard, Cheryl A. Hillery, Hao Xu, Anne C. Frei, Nancy J. Wandersee, Deron W. Jones, Madelyn S. Hanson

Hemolysis can saturate the hemoglobin (Hb)/heme scavenging system, resulting in increased circulating cell-free Hb (CF-Hb) in hereditary and acquired hemolytic disease. While recent studies have suggested a central role for intravascular hemolysis an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09f4ff8c407dee958042270df42cf5d
https://europepmc.org/articles/PMC3543667/

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Evidence for Transient Acute Liver Injury in Mouse Models of Sickle Cell Disease during Steady State Health

Autor: Dawn Retherford, Cheryl A. Hillery, Thomas D. Foster, Sandra L. Holzhauer, Nancy J. Wandersee

Publikováno v: Blood. 124:1373-1373

Individuals with sickle cell disease experience episodes of acute vaso-occlusive complications interspersed by periods of feeling well and apparent health during “steady state”. It is likely that episodic and subclinical sickling and vaso-occlusi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cafedb6fd1758ca756316ed9fb661807
https://doi.org/10.1182/blood.v124.21.1373.1373

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Dietary Supplementation with Docosahexanoic Acid (DHA) Improves RBC Flexibility and Reduces Cold Hypersensitivity in Mice with Sickle Cell Disease

Autor: Neil Hogg, Cheryl L. Stucky, Suilan Zheng, George Lykotrafitis, Philip S. Low, Cheryl A. Hillery, Katie Giger, Madelyn S. Hanson, Jamie L. Maciaszek, Michael C. Larson, Dawn Retherford, Nancy J. Wandersee, Barbara Mickelson

Publikováno v: Blood. 120:2116-2116

Abstract 2116 Humans and mice with sickle cell disease (SCD) have RBC stiffness, multiorgan and vascular pathology, and complex pain syndromes. Omega-3 fatty acids, such as docosahexanoic acid (DHA), are essential fatty acids that have anti-inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e03874f7ce9a5bddcba5c743e7a93783
https://doi.org/10.1182/blood.v120.21.2116.2116

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