Výsledky vyhledávání - "Dawn R Cochrane"

Akademický článek

STING pathway expression in low‐grade serous carcinoma of the ovary: an unexpected therapeutic opportunity?

Autor: Jutta Huvila, Dawn R Cochrane, Monica Ta, Christine Chow, Kendall Greening, Samuel Leung, Anthony N Karnezis, Analisa DiFeo, David G Huntsman

Publikováno v: The Journal of Pathology: Clinical Research, Vol 7, Iss 6, Pp 548-555 (2021)

Abstract Ovarian carcinoma histotypes are distinct diseases with variable clinical outcomes and response to treatment. There is a need for new subtype‐specific treatment modalities, especially for women with widespread and chemo‐resistant disease

Externí odkaz: https://doaj.org/article/d0a536b413fe4de3a25e878efa4fee34

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Akademický článek

Adult‐type granulosa cell tumor of the ovary: a FOXL2‐centric disease

Publikováno v: The Journal of Pathology: Clinical Research, Vol 7, Iss 3, Pp 243-252 (2021)

Abstract Adult‐type granulosa cell tumors (aGCTs) account for 90% of malignant ovarian sex cord‐stromal tumors and 2–5% of all ovarian cancers. These tumors are usually diagnosed at an early stage and are treated with surgery. However, one‐th

Externí odkaz: https://doaj.org/article/119bf70995b744d0addb4d02ce2fc2fa

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Akademický článek

Type-specific cell line models for type-specific ovarian cancer research.

Autor: Michael S Anglesio, Kimberly C Wiegand, Nataliya Melnyk, Christine Chow, Clara Salamanca, Leah M Prentice, Janine Senz, Winnie Yang, Monique A Spillman, Dawn R Cochrane, Karey Shumansky, Sohrab P Shah, Steve E Kalloger, David G Huntsman

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e72162 (2013)

BACKGROUND:OVARIAN CARCINOMAS CONSIST OF AT LEAST FIVE DISTINCT DISEASES: high-grade serous, low-grade serous, clear cell, endometrioid, and mucinous. Biomarker and molecular characterization may represent a more biologically relevant basis for group

Externí odkaz: https://doaj.org/article/65b8614f42c2490cb32181534ad23c9d

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Akademický článek

Correction: Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research.

Publikováno v: PLoS ONE, Vol 8, Iss 9 (2013)

[This corrects the article on p. e72162 in vol. 8.].

Externí odkaz: https://doaj.org/article/810ffd40af81465bac50d7f72cebc901

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Akademický článek

miR-200c targets a NF-κB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer.

Autor: Erin N Howe, Dawn R Cochrane, Diana M Cittelly, Jennifer K Richer

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e49987 (2012)

Anoikis is apoptosis initiated upon cell detachment from the native extracellular matrix. Since survival upon detachment from basement membrane is required for metastasis, the ability to resist anoikis contributes to the metastatic potential of breas

Externí odkaz: https://doaj.org/article/b66ac38e35ee4695873797c718b0ab06

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