Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Dawn Macdonald"'
Autor:
Faisal Bin Rashed, Diana Diaz-Dussan, Fatemeh Mashayekhi, Dawn Macdonald, Patrick Nicholas Nation, Xiao-Hong Yang, Sargun Sokhi, Alexandru Cezar Stoica, Hassan El-Saidi, Carolynne Ricardo, Ravin Narain, Ismail Hassan Ismail, Leonard Irving Wiebe, Piyush Kumar, Michael Weinfeld
Publikováno v:
Redox Biology, Vol 52, Iss , Pp 102300- (2022)
Solid tumours are often poorly oxygenated, which confers resistance to standard treatment modalities. Targeting hypoxic tumours requires compounds, such as nitroimidazoles (NIs), equipped with the ability to reach and become activated within diffusio
Externí odkaz:
https://doaj.org/article/ca3feb48a8764c959214901ce3f5c81e
Autor:
Faisal Bin Rashed, Alexandru Cezar Stoica, Dawn MacDonald, Hassan El-Saidi, Carolynne Ricardo, Bhumi Bhatt, Jack Moore, Diana Diaz-Dussan, Nirilanto Ramamonjisoa, Yvonne Mowery, Sambasivarao Damaraju, Richard Fahlman, Piyush Kumar, Michael Weinfeld
Publikováno v:
Redox Biology, Vol 44, Iss , Pp 101986- (2021)
Externí odkaz:
https://doaj.org/article/389dcf357e7845c4bf93640e9c31345d
Autor:
Faisal Bin Rashed, Alexandru Cezar Stoica, Dawn MacDonald, Hassan El-Saidi, Carolynne Ricardo, Bhumi Bhatt, Jack Moore, Diana Diaz-Dussan, Nirilanto Ramamonjisoa, Yvonne Mowery, Sambasivarao Damaraju, Richard Fahlman, Piyush Kumar, Michael Weinfeld
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101905- (2021)
Tumour hypoxia negatively impacts therapy outcomes and continues to be a major unsolved clinical problem. Nitroimidazoles are hypoxia selective compounds that become entrapped in hypoxic cells by forming drug-protein adducts. They are widely used as
Externí odkaz:
https://doaj.org/article/acd2f8f486bc4b74a03fa90d0932af06
Autor:
Dawn MacDonald
Publikováno v:
Refuge, Vol 5, Iss 4 (1986)
Externí odkaz:
https://doaj.org/article/c361649104094a59882b9f25737fdfd3
Publikováno v:
ACS Central Science. 8:1527-1536
Chemical biology has revealed the importance of sialic acids as a major signal in physiology and disease. The terminal modification α-2,6-sialic acid is controlled by the enzymes ST6GAL1 and ST6GAL2. Dysregulation of this glycan impacts immunologica
Autor:
Diana Diaz-Dussan, Yi-Yang Peng, Faisal Bin Rashed, Dawn Macdonald, Michael Weinfeld, Piyush Kumar, Ravin Narain
Publikováno v:
Molecular Pharmaceutics.
Autor:
Dawn Macdonald
Publikováno v:
Physics Today. 76:10-11
Autor:
Nick Catalano, Mina Dousti, Selina Heidinger, Liz Hydesmith, Dawn MacDonald, Taylor Neustaeter, Lara Rosenoff Gauvin
Publikováno v:
Anthropology Now. 13:87-97
The dominant paradigm is that miRNA binding to mRNA represses protein expression. Activation by miRNA has been observed in select circumstances (quiescent cells, mitochondria), but is not thought a feature of miRNA action in actively dividing cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a399ae5d49ed49a4a79a541f8b9872
https://doi.org/10.1101/2022.04.01.486772
https://doi.org/10.1101/2022.04.01.486772
Publikováno v:
Journal of Biological Chemistry. 299:104229