Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dawn M. Myscofski"'
Autor:
Stephanie V. Trefry, Mayanka Awasthi, Christy N. Raney, Amy L. Cregger, Chase A. Gonzales, Brittney L. Layton, Robert N. Enamorado, Nelson A. Martinez, Deborah S. Gohegan, Masoudeh Masoud-Bahnamiri, Jennifer Y. Cho, Dawn M. Myscofski, Tinoush Moulaei, Natasza E. Ziółkowska, Scott J. Goebel, Seth Lederman, Sina Bavari, Farooq Nasar
Publikováno v:
mSphere, Vol 9, Iss 12 (2024)
ABSTRACT Recombinant chimeric horsepox virus (TNX-801) is a preclinical vaccine in development against mpox and smallpox. In this report, we investigated the potential phenotypic differences in in vitro and in vivo models between TNX-801 and older va
Externí odkaz:
https://doaj.org/article/7144c18377e74ad4a34bf65844c292b2
Publikováno v:
Protein Expression and Purification. 20:112-123
Streptococcus gordonii (S. gordonii) has been used as a gram-positive bacterial expression vector for secreted or surface-anchored recombinant proteins. Fusion of the gram-positive bacterial N-terminal signal sequence to the target protein is all tha
Autor:
Dawn M. Myscofski, Dennis E. Hruby
Publikováno v:
Protein Expression and Purification. 14:409-417
Using a conserved pathway for surface protein extrusion, a system has been developed for the expression and secretion of proteins from gram-positive bacteria. As proof-of-concept, the Streptococcus gordonii Challis strain has been engineered to expre
Publikováno v:
Preparative biochemistrybiotechnology. 31(3)
A gram-positive bacterial expression vector using Streptococcus gordonii has been developed for expression and secretion, or surface anchoring of heterologous proteins. This system, termed Surface Protein Expression system or SPEX, has been used to e