Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Dawn M. Dawson"'
Autor:
Julianne N.P. Smith, Dawn M. Dawson, Kelsey F. Christo, Alvin P. Jogasuria, Mark J. Cameron, Monika I. Antczak, Joseph M. Ready, Stanton L. Gerson, Sanford D. Markowitz, Amar B. Desai
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
The splenic microenvironment regulates hematopoietic stem and progenitor cell (HSPC) function, particularly during demand-adapted hematopoiesis; however, practical strategies to enhance splenic support of transplanted HSPCs have proved elusive. We ha
Externí odkaz:
https://doaj.org/article/6ee60674db1947ed9c4037c1257d9dd7
Autor:
Amar Desai, Yongyou Zhang, Youngsoo Park, Dawn M. Dawson, Gretchen A. Larusch, Lakshmi Kasturi, David Wald, Joseph M. Ready, Stanton L. Gerson, Sanford D. Markowitz
Publikováno v:
Haematologica, Vol 103, Iss 6 (2018)
Hematopoietic stem cell transplantation following myeloablative chemotherapy is a curative treatment for many hematopoietic malignancies. However, profound granulocytopenia during the interval between transplantation and marrow recovery exposes recip
Externí odkaz:
https://doaj.org/article/614605af3a4a45caa1781d8896725f51
Autor:
Won Jin Ho, Julianne N P Smith, Young Soo Park, Matthew Hadiono, Kelsey Christo, Alvin Jogasuria, Yongyou Zhang, Alyssia V Broncano, Lakshmi Kasturi, Dawn M Dawson, Stanton L Gerson, Sanford D Markowitz, Amar B Desai
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268787 (2022)
Emerging evidence implicates the eicosanoid molecule prostaglandin E2 (PGE2) in conferring a regenerative phenotype to multiple organ systems following tissue injury. As aging is in part characterized by loss of tissue stem cells' regenerative capaci
Externí odkaz:
https://doaj.org/article/1d5311542b3a499489eef5c722b323e2
Autor:
Dawn M. Dawson, Varadan, Kishore Guda, Salendra Singh, Amitabh Chak, Andrew Blum, Omar Martinez-Uribe, Durgadevi Ravillah, Peronne Joseph, Thomas LaFramboise, Srividya Venkitachalam, Hogue Ja, Joseph Willis, D. B. Babu, Adam Kresak, Katherine S. Garman, Katabathula Rm, Miao Y, Udhayakumar B
Esophageal adenocarcinoma (EAC), a highly aggressive cancer with limited therapeutic options, often arises in the backdrop of a molecularly-complex esophageal metaplasia disorder, Barrett’s Esophagus (BE). Using transcriptomics and systems biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd008e170a31adb7fb82b7542695837
https://doi.org/10.1101/2021.05.13.444044
https://doi.org/10.1101/2021.05.13.444044
Autor:
Lakshmi Kasturi, Yongyou Zhang, Julianne N.P. Smith, Young Soo Park, Won Jin Ho, Matthew Hadiono, Kelsey F. Christo, Amar Desai, Alvin P. Jogasuria, Sanford D. Markowitz, Dawn M. Dawson, Stanton L. Gerson, Alyssia V. Broncano
Emerging evidence implicates the eicosanoid molecule prostaglandin E2 (PGE2) in conferring a regenerative phenotype to multiple organ systems following tissue injury. As aging is in part characterized by loss of tissue stem cells’ regenerative capa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a423772524a11b5201e77aef12572a3a
https://doi.org/10.1101/2020.12.22.424017
https://doi.org/10.1101/2020.12.22.424017
Autor:
Sanford D. Markowitz, Dawn M. Dawson, Julianne N.P. Smith, Kelsey F. Christo, Amar Desai, Joseph M. Ready, Stanton L. Gerson, Alvin P. Jogasuria, Monika I. Antczak, Mark J. Cameron
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 6 (2021)
JCI Insight, Vol 6, Iss 6 (2021)
The splenic microenvironment regulates hematopoietic stem and progenitor cell (HSPC) function, particularly during demand-adapted hematopoiesis, however practical strategies to enhance splenic support of transplanted HSPCs have proven elusive. We hav
Autor:
Nancy L. Cho, Jiping Wang, Kisha Mitchell-Richards, Dawn M. Dawson, Sanford D. Markowitz, Ann G. Zauber, Amitabh Srivastava, Monica M. Bertagnolli, Meier Hsu
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 27:728-736
Background: The Adenoma Prevention with Celecoxib (APC) Trial showed that cyclooxygenase-2 (Cox-2) inhibitor, celecoxib, decreased adenoma development in patients at high risk for colorectal cancer. A prospectively planned analysis of the APC Trial t
Autor:
Dawn M. Dawson, Joseph M. Ready, Sanford D. Markowitz, Amar Desai, Gretchen A. LaRusch, Yongyou Zhang, Lakshmi Kasturi, Young Soo Park, David N. Wald, Stanton L. Gerson
Publikováno v:
Haematologica
Hematopoietic stem cell transplantation following myeloablative chemotherapy is a curative treatment for many hematopoietic malignancies. However, profound granulocytopenia during the interval between transplantation and marrow recovery exposes recip
Autor:
Emiko Miller, Preethy Sridharan, Edwin Vázquez-Rosa, Stephen P. Fink, Coral J. Cintrón-Pérez, Joseph M. Ready, Margaret E. Flanagan, Yeo Jung Koh, Dawn M. Dawson, Sanford D. Markowitz, Hisashi Fujioka, Hongyun Li, Sarah Barker, Kathryn Franke, Andrew A. Pieper, Min-Kyoo Shin
Publikováno v:
Biological Psychiatry. 89:S309
Autor:
Sanford D. Markowitz, Peiying Yang, Jill S. Barnholtz-Sloan, Earl Lawrence, Yanwen Chen, Levy Kopelovich, Adam Kresak, Stephen P. Fink, Dawn M. Dawson, Yongyou Zhang, Joseph Willis
Publikováno v:
Carcinogenesis. 36:291-298
Non-steroidal anti-inflammatory drugs prevent colorectal cancer by inhibiting cyclooxygenase (COX) enzymes that synthesize tumor-promoting prostaglandins. 15-hydroxyprostaglandin dehydrogenase (15-PGDH) is a tumor suppressor that degrades tumor-promo