Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Dawn M. Clifford"'
Publikováno v:
Current biology : CB. 29(6)
Summary In animals and fungi, cytokinesis is facilitated by the constriction of an actomyosin contractile ring (CR) [ 1 ]. In Schizosaccharomyces pombe, the CR forms mid-cell during mitosis from clusters of proteins at the medial cell cortex called n
Autor:
Maria Almonacid, Damarys Loew, Jun-Song Chen, Anne Paoletti, Séverine Celton-Morizur, Adeline Mayeux, Dawn M. Clifford, Kathleen L. Gould, Jennifer L. Jakubowski, Florent Dingli
Publikováno v:
Current Biology-CB
Current Biology-CB, Elsevier, 2011, 21 (6), pp.473-479. ⟨10.1016/j.cub.2011.02.003⟩
Current Biology-CB, Elsevier, 2011, 21 (6), pp.473-479. ⟨10.1016/j.cub.2011.02.003⟩
In eukaryotes, cytokinesis generally involves an acto-myosin ring, the contraction of which promotes daughter cells segregation. Assembly of the contractile ring is tightly controlled in space and time (see[1–4] for reviews). In the fission yeast,
Publikováno v:
Molecular Biology of the Cell. 20:3646-3659
The chromosomal passenger complex (CPC) regulates various events in cell division. This complex is composed of a catalytic subunit, Aurora B kinase, and three nonenzymatic subunits, INCENP, Survivin, and Borealin. Together, these four subunits interd
Autor:
Dannel McCollum, Dawn M. Clifford, Anna Feoktistova, Kathleen L. Gould, Chun-Ti Chen, Jun-Song Chen, Young-Sam Shim
Publikováno v:
Current Biology. 18:1594-1599
SummaryCdc14-family phosphatases play a conserved role in promoting mitotic exit and cytokinesis by dephosphorylating substrates of cyclin-dependent kinase (Cdk). Cdc14-family phosphatases have been best studied in yeast (for review, see [1, 2]), whe
Autor:
Benjamin Wolfe, Kathleen L. Gould, Rachel H. Roberts-Galbraith, John R. Yates, Dawn M. Clifford, W. Hayes McDonald
Publikováno v:
The Journal of Cell Biology
Cdc14 phosphatases antagonize cyclin-dependent kinase–directed phosphorylation events and are involved in several facets of cell cycle control. We investigate the role of the fission yeast Cdc14 homologue Clp1/Flp1 in cytokinesis. We find that Clp1
Publikováno v:
Journal of Biological Chemistry. 279:6163-6170
In Saccharomyces cerevisiae, the cellular single-stranded DNA-binding protein replication protein A (RPA) becomes phosphorylated during meiosis in two discrete reactions. The primary reaction is first observed shortly after cells enter the meiotic pr
Publikováno v:
Nucleic Acids Research. 29:4808-4817
Phosphorylation of the cellular single-stranded DNA-binding protein, replication protein A (RPA), occurs during normal mitotic cell cycle progression and also in response to genotoxic stress. In budding yeast, these reactions require the ATM homolog
Autor:
Dawn M. Clifford, Benjamin Wolfe, Jun-Song Chen, Kathleen L. Gould, Rachel H. Roberts, Dannel McCollum, Chun-Ti Chen, Anna Feoktistova
Publikováno v:
Biochemical Society Transactions. 36:436-438
The periodicity of CDKs (cyclin-dependent kinases) regulates most cell cycle transitions including cytokinesis. High Cdk1 activity promotes cytoskeletal rearrangements necessary for cell division while at the same time ensuring that cytokinesis does
Publikováno v:
The FASEB Journal. 24
Autor:
George S. Brush, Susanne Hoffmann-Benning, Kathryn E. Gardner, Dawn M. Clifford, Kara E. Stark
Publikováno v:
Cell cycle (Georgetown, Tex.). 4(12)
In budding yeast, the meiosis-specific protein kinase Ime2 is required for normal meiotic progression. Current evidence suggests that Ime2 is functionally related to Cdc28, the major cyclin-dependent kinase in yeast that is essential for both cell cy