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Publikováno v:
International Journal of Pharmaceutics. 104:169-174
Solid dispersions of CI-987 (5-{[3,5-bis(l,l-dimethylethyI)-4-hydroxyphcnyl]-methylene}-2,4-thiazolidinedione) having varying concentrations of polyvinylpyrrolidone (PVP K 28–32), were prepared in an attempt to improve the dissolution rate of CI-98