Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Dawn K. Reichenbach"'
Autor:
Erica L. Unger, David J. Eve, Xiomara A. Perez, Dawn K. Reichenbach, Yanqun Xu, Michael K. Lee, Anne M. Andrews
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 2, Pp 431-443 (2006)
Genetic and biochemical abnormalities associated with α-synuclein are implicated in the etiology of Parkinson's disease (PD). In this study, altered locomotor behavior linked to the expression of mutant or wildtype human α-synuclein was investigate
Externí odkaz:
https://doaj.org/article/4f006b12e90a44ca98aceff5367c5f68
Autor:
Jonathan S. Serody, Ameeta Kelekar, Brent H. Koehn, Brian T. Fife, Laurence A. Turka, Asim Saha, Govindarajan Thangavelu, Keli L. Hippen, Sudha Kumari, Angela Panoskaltsis-Mortari, Andrew Kemal Kirchmeier, Mark J. Osborn, Cameron McDonald-Hyman, David H. Munn, Jason S. Mitchell, Guoan Zhang, Bruce R. Blazar, Colby J. Feser, Michael Loschi, Michael L. Dustin, Jiqiang Lin, James E. Muller, Thomas A. Neubert, Hongbo Chi, Michelle J. Smith, Dawn K. Reichenbach
Publikováno v:
Journal of Clinical Investigation. 128:4604-4621
Regulatory T cells (Tregs) are critical for maintaining immune homeostasis. However, current Treg immunotherapies do not optimally treat inflammatory diseases in patients. Understanding the cellular processes that control Treg function may allow for
Autor:
Kishore B. Challagundla, Yvonne A. Efebera, Apollinaire Ngankeu, Stefano Volinia, Bruce R. Blazar, Parvathi Ranganathan, Sabrina L Garman, Lucia Casadei, Muller Fabbri, Pier Paolo Leoncini, Nina C. Zitzer, Jessica Hofstetter, Steven M. Devine, Dawn K. Reichenbach, Xueyan Yu, Ramiro Garzon, Amy S. Ruppert
Publikováno v:
The Journal of Immunology. 198:2500-2512
Acute graft-versus-host disease (aGVHD) continues to be a frequent and devastating complication of allogeneic hematopoietic stem cell transplantation (HSCT), posing as a significant barrier against the widespread use of HSCTs as a curative modality.
Autor:
Michelle J Smith, Dawn K Reichenbach, Sarah L. Parker, Mahmood Mohtashami, Heather E. Stefanski, Kristin Ann Hogquist, Georg A. Holländer, Juan Carlos Zúñiga-Pflücker, Bruce R Blazar
The inclusion of in vitro derived T cell progenitor (proT) therapy with hematopoietic stem cell transplant (HSCT) aids in the recovery of the thymus damaged by total body irradiation and improves de novo thymopoiesis. To understand the interaction be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82a769c97ccbfcb9b80e9d94f182880
https://ora.ox.ac.uk/objects/uuid:419bd563-3006-4473-a4af-c86163a26660
https://ora.ox.ac.uk/objects/uuid:419bd563-3006-4473-a4af-c86163a26660
Autor:
Keli L. Hippen, Sophie Paczesny, Brad Griesenauer, Jinfeng Yang, Dawn K. Reichenbach, Abdulraouf Ramadan, Michael Loschi, Jilu Zhang, Hong Liu, Bruce R. Blazar
Soluble stimulation–2 (ST2) is increased during graft-versus-host disease (GVHD), while Tregs that express ST2 prevent GVHD through unknown mechanisms. Transplantation of Foxp3(–) T cells and Tregs that were collected and sorted from different Fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87db675d92dcb5c23518d1da4bebbe3e
https://europepmc.org/articles/PMC6483518/
https://europepmc.org/articles/PMC6483518/
Autor:
Aditya Misra, Christopher Borges, Bruce R. Blazar, Dawn K. Reichenbach, Laurence A. Turka, Beom Seok Kim
Publikováno v:
Transplant International. 29:930-940
MyD88 signaling directly promotes T cell survival, and is required for optimal T cell responses to pathogens. To examine the role of T cell intrinsic MyD88 signals in transplantation, we studied mice with targeted T cell-specific MyD88 deletion. Cont
Autor:
Hemamalini Bommiasamy, Rachel D. Kuns, Kate H. Gartlan, Mary Owen, Jonathan S. Serody, Geoffrey R. Hill, Paul S. Foster, Karshing Chang, Antiopi Varelias, Yuri Fedoriw, Michael Zaiken, Bruce R. Blazar, James M. Coghill, Tatjana Banovic, Katelyn Paz, Thomas C. Shea, Kimberly Wehner, Dawn K. Reichenbach, Andrew N. Wilkinson, Maximilian Plank, Andrew D. Clouston, Faith Brianne Buchanan
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18(4)
Graft-versus-host disease (GVHD) is the major cause of non-relapse morbidity and mortality after allogeneic stem cell transplant (allo-SCT). Chronic cutaneous manifestations of GVHD are common late after allo-SCT with limited treatment options beyond
Autor:
Rachelle G. Veenstra, Angela Panoskaltsis-Mortari, Stefanie Sarantopoulos, Joseph H. Antin, Ryan Flynn, Geoff R. Hill, Kelli P. A. MacDonald, Dawn K. Reichenbach, Jonathan S. Serody, Ivan Maillard, Robert J. Soiffer, William J. Murphy, David H. Munn, Leo Luznik, John Koreth, Jason A. Dubovsky, Bruce R. Blazar, Gordon J. Freeman, Patricia A. Taylor, Jing Du, Corey Cutler, Jerome Ritz, John C. Byrd
Publikováno v:
Blood. 123:3988-3998
Chronic graft-versus-host disease (cGVHD) is a leading cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Having shown that germinal center (GC) formation and immunoglobulin deposition are required for multiorg
Autor:
Keli L. Hippen, Hong Liu, Sophie Paczesny, Michael Loschi, Brad Griesenauer, Jinfeng Yang, Jilu Zhang, Bruce R. Blazar, Abdulraouf Ramadan, Dawn K. Reichenbach
Publikováno v:
Blood. 132:66-66
Allogeneic hematopoietic cell transplantation (allo-HCT) is an essential therapeutic modality for patients with hematological malignancies and benign blood disorders. Unfortunately, acute graft-versus-host disease (aGVHD) remains the major complicati
Cell damage and death releases “alarmins”, or self-derived immunomodulatory molecules, that recruit and activate the immune system. Unfortunately, numerous processes critical to the transplantation of allogeneic materials result in the destructio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e5df26ca68cfdfe7d29f1ed365bc89
https://europepmc.org/articles/PMC5124552/
https://europepmc.org/articles/PMC5124552/