Výsledky vyhledávání - "Dawn J. Howard"

Akademický článek

A Population Genomics Analysis of the Native Irish Galway Sheep Breed

Autor: Gillian P. McHugo, Sam Browett, Imtiaz A. S. Randhawa, Dawn J. Howard, Michael P. Mullen, Ian W. Richardson, Stephen D. E. Park, David A. Magee, Erik Scraggs, Michael J. Dover, Carolina N. Correia, James P. Hanrahan, David E. MacHugh

Publikováno v: Frontiers in Genetics, Vol 10 (2019)

The Galway sheep population is the only native Irish sheep breed and this livestock genetic resource is currently categorised as ‘at-risk’. In the present study, comparative population genomics analyses of Galway sheep and other sheep populations

Externí odkaz: https://doaj.org/article/ceae5b458a0b45e8a9dcde0625d3b39d

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Akademický článek

Single nucleotide polymorphisms in the insulin-like growth factor 1 (IGF-1) gene are associated with performance in Holstein-Friesian dairy cattle

Autor: Michael Paul Mullen, Donagh P. Berry, Dawn J. Howard, Michael G. Diskin, Ciaran O. Lynch, Linda eGiblin, David A. Kenny, David A. Magee, Kieran G. Meade, Sinead M. Waters

Publikováno v: Frontiers in Genetics, Vol 2 (2011)

Insulin-like growth factor 1 (IGF-1) has been shown to be associated with fertility, growth and development in cattle. The aim of this study was to 1) identify novel single nucleotide polymorphisms (SNPs) in the bovine IGF-1 gene and alongside previo

Externí odkaz: https://doaj.org/article/f2aae8e371d5406ba135a5de52b97a24

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Single nucleotide polymorphisms in the imprinted bovine insulin-like growth factor 2 receptor gene (IGF2R) are associated with body size traits in Irish Holstein-Friesian cattle

Autor: David A. Magee, Charles Spillane, Klaudia M Sikora, Ross D Evans, Michael P. Mullen, Dawn J. Howard, Donagh P. Berry, E. W. Berkowicz, David E. MacHugh

Publikováno v: Animal Genetics. 43:81-87

Summary The regulation of the bioavailability of insulin-like growth factors (IGFs) is critical for normal mammalian growth and development. The imprinted insulin-like growth factor 2 receptor gene (IGF2R) encodes a transmembrane protein receptor tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::271a7f78e0bc4f79d4be86bd4efdcde7
https://doi.org/10.1111/j.1365-2052.2011.02211.x

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Associations between newly discovered polymorphisms in the Bos taurusgrowth hormone receptor gene and performance traits in Holstein-Friesian dairy cattle

Autor: Matthew S. McCabe, Donagh P. Berry, Linda Giblin, David A. Magee, Dawn J. Howard, S. M. Waters, David E. MacHugh

Publikováno v: Animal Genetics. 42:39-49

Summary Variations in the growth hormone receptor (GHR) gene sequence are associated with performance traits in cattle. For example, the single nucleotide polymorphism (SNP) F279Y in transmembrane exon 8 has a strong association with milk yield. In t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c13b20814f47b317340a138747670f9d
https://doi.org/10.1111/j.1365-2052.2010.02087.x

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Single nucleotide polymorphisms in the growth hormone and insulin-like growth factor-1 genes are associated with milk production, body condition score and fertility traits in dairy cows

Autor: B Horan, David A. Kenny, Michael P. Mullen, Dawn J. Howard, Padraic O'Boyle, Michael G. Diskin, C.O. Lynch, F Buckley, Sinead M. Waters

Publikováno v: Genetics and Molecular Research. 10:1819-1830

The somatotrophic axis (GH-IGF) is a key regulator of animal growth and development, affecting performance traits that include milk production, growth rate, body composition, and fertility. The aim of this study was to quantify the association of pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b9cce78d2565c4cbd137432b8b5cc8
https://doi.org/10.4238/vol10-3gmr1173

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Polymorphisms in the bovine lactoferrin promoter are associated with reproductive performance and somatic cell count

Autor: Torres Sweeney, Donagh P. Berry, Linda Giblin, Fiona O'Halloran, Bojlul Bahar, Dawn J. Howard

Publikováno v: Journal of Dairy Science. 93:1253-1259

Lactoferrin plays an important role in the innate immune system, with well-characterized antibacterial, antiviral, and immune modulatory properties. The objective of this study was to determine the allele and haplotype frequency of polymorphisms at p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aff8f590cf5cf686ae0e2e91b9c6af0
https://doi.org/10.3168/jds.2009-2699

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Investigation of prolific sheep from UK and Ireland for evidence on origin of the mutations in BMP15 (FecXG, FecXB) and GDF9 (FecGH) in Belclare and Cambridge sheep

Autor: Michael P. Mullen, James P Hanrahan, Richard Powell, Dawn J. Howard

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e53172 (2013)

peer-reviewed This paper concerns the likely origin of three mutations with large effects on ovulation rate identified in the Belclare and Cambridge sheep breeds; two in the BMP15 gene (FecXG and FecXB) and the third (FecGH) in GDF9. All three mutati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966555f429db83239d11550003d190c1
http://research.thea.ie/handle/20.500.12065/3386

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Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples

Autor: Paul A. McGettigan, Michael P. Mullen, David E. MacHugh, Aideen P. Killeen, Donagh P. Berry, M. C. Lucy, Stephen D. E. Park, Dawn J. Howard, Christopher J. Creevey, David A. Magee, Matthew S. McCabe, Sinead M. Waters

Publikováno v: BMC Genomics
BMC Genomics, Vol 13, Iss 1, p 16 (2012)

peer-reviewed Background: The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within this axis is an at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2830ed0df181f7c6e829b6e8bc36a0af
http://research.thea.ie/handle/20.500.12065/3385

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Single nucleotide polymorphisms in the insulin-like growth factor 1 (IGF-1) gene are associated with performance in Holstein-Friesian dairy cattle

Autor: C.O. Lynch, Michael P. Mullen, David A. Kenny, Kieran G. Meade, Sinead M. Waters, Linda Giblin, Michael G. Diskin, Dawn J. Howard, David A. Magee, Donagh P. Berry

Publikováno v: Frontiers in Genetics, Vol 2 (2011)
Frontiers in Genetics

peer-reviewed Insulin-like growth factor 1 (IGF-1) has been shown to be associated with fertility, growth, and development in cattle. The aim of this study was to (1) identify novel single nucleotide polymorphisms (SNPs) in the bovine IGF-1 gene and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfede55665a34402875157f32061c806
http://journal.frontiersin.org/Journal/10.3389/fgene.2011.00003/full

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Single nucleotide polymorphisms at the imprinted bovine insulin-like growth factor 2 ( igf2) locus are associated with dairy performance in irish holstein-friesian cattle

Autor: E. W. Berkowicz, Ross D Evans, Dawn J. Howard, Donagh P. Berry, David A. Magee, David E. MacHugh, Klaudia M Sikora, Charles Spillane, Michael P. Mullen

The imprinted insulin-like growth factor 2 gene (IGF2) encodes a fetal mitogenic hormone protein (IGF-II) and has previously been shown to be associated with performance in dairy cattle. In this study we assessed genotype-phenotype associations betwe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4098f41c771ee519b043a411d7f7a3
http://hdl.handle.net/10379/10415

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