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pro vyhledávání: '"Dawn J. Brooks"'
Autor:
Jacques R. Fresco, Dawn J. Brooks
Publikováno v:
Molecular & Cellular Proteomics. 1:125-131
Analysis of extant proteomes has the potential of revealing how amino acid frequencies within proteins have evolved over biological time. Evidence is presented here that cysteine, tyrosine, and phenylalanine residues have substantially increased in f
Publikováno v:
Gene. 225:97-105
Screening of cDNA libraries for the homologous vertebrate proteins high mobility group (HMG) 1 and 2 using DNA probes based on the coding sequences is likely to result in isolation of both HMG1 and HMG2 clones, as well as pseudogenes, which may be tr
Autor:
Dawn J. Brooks, Eric A. Gaucher
The last universal ancestor (LUA) represents a relatively accessible theoretical intermediary between extant cellular organisms and early, precellular ‘life’. In a previous study, the expectation-maximization (EM) approach was used to infer ances
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ef499e6b681d8880545602614544da0
https://doi.org/10.1093/acprof:oso/9780199299188.003.0017
https://doi.org/10.1093/acprof:oso/9780199299188.003.0017
Autor:
Dawn J. Brooks, Jacques R. Fresco
Publikováno v:
Gene. 303
The possibility that RNY pattern bias in extant sequences is a remnant of more pronounced bias of this type in early ancestors was investigated. To this end, conserved residues (those residues for which the inferred ancestral and known descendant ami
Publikováno v:
Molecular biology and evolution. 19(10)
To understand more fully how amino acid composition of proteins has changed over the course of evolution, a method has been developed for estimating the composition of proteins in an ancestral genome. Estimates are based upon the composition of conse