Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Dawn Gibbs-Howe"'
Autor:
Gavuthami Murugesan, Rachel L. Paterson, Rakesh Kulkarni, Veronica Ilkow, Richard J. Suckling, Mary M. Connolly, Vijaykumar Karuppiah, Robert Pengelly, Archana Jadhav, Jose Donoso, Tiaan Heunis, Wilawan Bunjobpol, Gwilym Philips, Kafayat Ololade, Daniel Kay, Anshuk Sarkar, Claire Barber, Ritu Raj, Carole Perot, Tressan Grant, Agatha Treveil, Andrew Walker, Marcin Dembek, Dawn Gibbs-Howe, Miriam Hock, Ricardo J. Carreira, Kate E. Atkin, Lucy Dorrell, Andrew Knox, Sarah Leonard, Mariolina Salio, Luis F. Godinho
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The non-polymorphic HLA-E molecule offers opportunities for new universal immunotherapeutic approaches to chronic infectious diseases. Chronic Hepatitis B virus (HBV) infection is driven in part by T cell dysfunction due to elevated levels o
Externí odkaz:
https://doaj.org/article/3dc727caf8474340a5e4d1bb478f8c46
Autor:
Claire Barber, Victoria Arena De Souza, Rachel L. Paterson, Magdalena Martin‐Urdiroz, Nitha Charles Mulakkal, Velupillai Srikannathasan, Mary Connolly, Gwilym Phillips, Tein Foong‐Leong, Robert Pengelly, Vijaykumar Karuppiah, Tressan Grant, Marcin Dembek, Anil Verma, Dawn Gibbs‐Howe, Thomas H. Blicher, Andrew Knox, Ross A. Robinson, David K. Cole, Sarah Leonard
Publikováno v:
European Journal of Immunology. 52:618-632
The nonpolymorphic class Ib molecule, HLA-E, primarily presents peptides from HLA class Ia leader peptides, providing an inhibitory signal to NK cells via CD94/NKG2 interactions. Although peptides of pathogenic origin can also be presented by HLA-E t