Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Dawn Garcia"'
Autor:
Funan He, Abhik M. Bandyopadhyay, Laura J. Klesse, Anna Rogojina, Sang H. Chun, Erin Butler, Taylor Hartshorne, Trevor Holland, Dawn Garcia, Korri Weldon, Luz-Nereida Perez Prado, Anne-Marie Langevin, Allison C. Grimes, Aaron Sugalski, Shafqat Shah, Chatchawin Assanasen, Zhao Lai, Yi Zou, Dias Kurmashev, Lin Xu, Yang Xie, Yidong Chen, Xiaojing Wang, Gail E. Tomlinson, Stephen X. Skapek, Peter J. Houghton, Raushan T. Kurmasheva, Siyuan Zheng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Subcutaneous patient-derived xenografts (PDXs) are an important tool for childhood cancer research. Here, we describe a resource of 68 early passage PDXs established from 65 pediatric solid tumor patients. Through genomic profiling of paired
Externí odkaz:
https://doaj.org/article/7acada1d5c1a4ea691eda4a7f049f2e0
Autor:
Anna Rogojina, Laura J. Klesse, Erin Butler, Jiwoong Kim, He Zhang, Xue Xiao, Lei Guo, Qinbo Zhou, Taylor Hartshorne, Dawn Garcia, Korri Weldon, Trevor Holland, Abhik Bandyopadhyay, Luz Perez Prado, Shidan Wang, Donghan M. Yang, Anne-Marie Langevan, Yi Zou, Allison C. Grimes, Chatchawin Assanasen, Vinod Gidvani-Diaz, Siyuan Zheng, Zhao Lai, Yidong Chen, Yang Xie, Gail E. Tomlinson, Stephen X. Skapek, Raushan T. Kurmasheva, Peter J. Houghton, Lin Xu
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108171- (2023)
Summary: Patient-derived xenografts (PDX) remain valuable models for understanding the biology and for developing novel therapeutics. To expand current PDX models of childhood leukemia, we have developed new PDX models from Hispanic patients, a subgr
Externí odkaz:
https://doaj.org/article/22cacf03f3b04f17bc8080bce501067f
Autor:
Kent E. Williams, Yi Zou, Bin Qiu, Tatsuyoshi Kono, Changyong Guo, Dawn Garcia, Hanying Chen, Tamara Graves, Zhao Lai, Carmella Evans-Molina, Yao-Ying Ma, Suthat Liangpunsakul, Weidong Yong, Tiebing Liang
Publikováno v:
Cells, Vol 13, Iss 1, p 89 (2023)
High levels of alcohol intake alter brain gene expression and can produce long-lasting effects. FK506-binding protein 51 (FKBP51) encoded by Fkbp5 is a physical and cellular stress response gene and has been associated with alcohol consumption and wi
Externí odkaz:
https://doaj.org/article/bd9ba3e9865a4a2db1ec431a34823b1f
Autor:
Nidhi Jariwala, Rachel G. Mendoza, Dawn Garcia, Zhao Lai, Mark A. Subler, Jolene J. Windle, Nitai D. Mukhopadhyay, Paul B. Fisher, Yidong Chen, Devanand Sarkar
Publikováno v:
Hepatology Communications, Vol 3, Iss 9, Pp 1258-1270 (2019)
Oncoprotein staphylococcal nuclease and tudor domain containing 1 (SND1) regulates gene expression at a posttranscriptional level in multiple cancers, including hepatocellular carcinoma (HCC). Staphylococcal nuclease (SN) domains of SND1 function as
Externí odkaz:
https://doaj.org/article/b7f4ac91fec745128b6416691f1b4ef9
Autor:
Yi Zou, Zhao Lai, Dawn Garcia, Theodore J. Price, Jennifer Mecklenburg, Gregory Dussor, Armen N. Akopian, Alexei V. Tumanov, Andi Wangzhou
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports
Scientific Reports
Many chronic pain conditions show sex differences in their epidemiology. This could be attributed to sex-dependent differential expression of genes (DEGs) involved in nociceptive pathways, including sensory neurons. This study aimed to identify sex-d
Autor:
Dawn Garcia, Yi Chen, Devanand Sarkar, Nitai D. Mukhopadhyay, Rachel G. Mendoza, Zhao Lai, Jolene J. Windle, Mark A. Subler, Paul B. Fisher, Nidhi Jariwala
Publikováno v:
Hepatology Communications, Vol 3, Iss 9, Pp 1258-1270 (2019)
Hepatology Communications
Hepatology Communications
Oncoprotein staphylococcal nuclease and tudor domain containing 1 (SND1) regulates gene expression at a posttranscriptional level in multiple cancers, including hepatocellular carcinoma (HCC). Staphylococcal nuclease (SN) domains of SND1 function as
Autor:
Shivani B. Ruparel, Korri S. Weldon, Nikita B. Ruparel, Dawn Garcia, Ashley R. Furr, Jacob T. Boyd, Alejandro Lopez Tobon, Erin E. Locke, Yi Zou, Kenneth M. Hargreaves, Claudia M Espitia Olaya, Zhao Lai, Peter M LoCoco
Publikováno v:
PAIN Reports, Vol 5, Iss 2, p e818 (2020)
Pain Reports
Pain Reports
Introduction:. Comprehensive mRNA sequencing is a powerful tool for conducting unbiased, quantitative differential gene expression analysis. However, the reliability of these data is contingent on the extraction of high-quality RNA from samples. Pres
Autor:
Chadia L. Robertson, Rachel G. Mendoza, Maaged A. Akiel, Devaraja Rajasekaran, Paul B. Fisher, Chunqing Guo, Xiang-Yang Wang, Mark A. Subler, Shah Giashuddin, Devanand Sarkar, Fang Yuan, Dawn Garcia, Hung I Harry Chen, Zhao Lai, Jolene J. Windle, Yi Chen, Nidhi Jariwala, Xia Li
Publikováno v:
Cancer Research. 77:4014-4025
Activation of IGF signaling is a major oncogenic event in diverse cancers, including hepatocellular carcinoma (HCC). In this setting, the insulin-like growth factor binding protein IGFBP7 inhibits IGF signaling by binding the IGF1 receptor (IGF1R), f
Autor:
John P. Spence, Tiebing Liang, Weidong Yong, Yi Zou, Hao Gu, Tamara Graves, Kent E. Williams, Zhao Lai, Bin Qiu, Jill L. Reiter, Lingling Zhang, Dawn Garcia, Paula J. Bice
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 9 (2018)
Frontiers in Genetics, Vol 9 (2018)
Humans show sex differences related to alcohol use disorders (AUD). Animal model research has the potential to provide important insight into how sex differences affect alcohol consumption, particularly because female animals frequently drink more th
Publikováno v:
Journal of visualized experiments : JoVE, vol 2017, iss 127
Antibody responses are accomplished through several critical B cell-intrinsic processes, including somatic hypermutation (SHM), class-switch DNA recombination (CSR), and plasma cell differentiation. In recent years, epigenetic modifications or factor