Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Dawn E. Verdugo"'
Autor:
Cheri L. Stowell, Theodore S. Widlanski, Robert M. Bigsby, Dawn E. Verdugo, Kevin K Barvian, Carolyn R. Bertozzi, Peter C.M. Young
Publikováno v:
Chemistry & Biology. 13(8):891-897
SummaryBisphenol A (BPA) is a widely used plasticizer whose estrogenic properties may impact hormone-responsive disorders and fetal development. In vivo, BPA appears to have greater activity than is suggested by its estrogen receptor (ER) binding aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270aa6a4831f5d37cc0b2eab7dedb240
Autor:
Kevin L. Moore, Brian Nicholas Cook, Joshua I. Armstrong, Dustin J. Maly, Carolyn R. Bertozzi, John Kehoe, Jonathan A. Ellman, Dawn E. Verdugo, Ying-Bin Ouyang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:329-332
Tyrosylprotein sulfotransferases (TPSTs) catalyze the sulfation of tyrosine residues within secreted and membrane-bound proteins. The modification modulates protein-protein interactions in the extracellular environment. Here we use combinatorial targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd927300ecbae226a232456b67434a6f
https://doi.org/10.1016/s0960-894x(01)00744-2
https://doi.org/10.1016/s0960-894x(01)00744-2
Autor:
Xue Ge, Katharine A. Winans, Joshua I. Armstrong, Dawn E. Verdugo, Julie A. Leary, Carolyn R. Bertozzi
Publikováno v:
Organic Letters. 3:2657-2660
[reaction: see text]. A library of potential bisubstrate analogue inhibitors (1) targeting sulfotransferase enzymes was generated by the chemoselective ligation of the PAPS mimic 2 with a panel of 447 aldehydes. Preliminary screening has identified c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd6b44fb885594d7bb447394c6feff9
https://doi.org/10.1021/ol0162217
https://doi.org/10.1021/ol0162217
Autor:
Dawn E. Verdugo, Mark T. Cancilla, Carolyn R. Bertozzi, Peter G. Schultz, Young-Tae Chang, Xue Ge, Nathanael S. Gray, Masahiko Negishi, Julie A. Leary
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce72f0b45766879cc7b4bda8f8c4e44
https://doi.org/10.1021/jm010171u
https://doi.org/10.1021/jm010171u
Autor:
Amanda J. Casella, Tatiana G. Levitskaia, Wes Hines, Ronald N. Christensen, James M. Peterson, Dawn E. Verdugo, Shane M. Peper, Christopher R. Orton, Carlos G. Fraga, Jon M. Schwantes, Samuel A. Bryan, Amanda M. Lines, Elizabeth A. Jordan, J. henkell
During FY 2010, work under the Spectroscopy-Based Process Monitoring task included ordering and receiving four fluid flow meters and four flow visible-near infrared spectrometer cells to be instrumented within the centrifugal contactor system at Paci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8678fcb0b78ffafbd7d54ea4f39585c1
https://doi.org/10.2172/1008246
https://doi.org/10.2172/1008246
Autor:
Dawn E. Verdugo, Julie A. Leary, Katharine A. Winans, Joshua I. Armstrong, Xue Ge, Carolyn R. Bertozzi
Publikováno v:
ChemInform. 32
A library of potential bisubstrate analogue inhibitors (1) targeting sulfotransferase enzymes was generated by the chemoselective ligation of the PAPS mimic 2 with a panel of 447 aldehydes. Preliminary screening has identified compounds that inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33eebe7abf0dee07ec14d38cd51d0bbc
https://doi.org/10.1002/chin.200148169
https://doi.org/10.1002/chin.200148169
Publikováno v:
Carbohydrate-Based Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5b152f752f55fcb244ed90e2734da67
https://doi.org/10.1002/3527602437.ch29
https://doi.org/10.1002/3527602437.ch29
Publikováno v:
The Journal of organic chemistry. 68(1)
Sulfotransferases catalyze the transfer of a sulfuryl group from the eukaryotic sulfate donor 3'-phosphoadenosine 5'-phosphosulfate to an acceptor biomolecule. Sulfotransferases have been linked with several disease states, prompting our investigatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc6b9c35b3598823bd58a66a42785c8
https://pubmed.ncbi.nlm.nih.gov/12515476
https://pubmed.ncbi.nlm.nih.gov/12515476
Autor:
Carolyn R. Bertozzi, Dawn E. Verdugo
Publikováno v:
Analytical biochemistry. 307(2)
Here we describe an efficient dot-blot assay for high-throughput screening of two enzymes, heparan sulfate N -deacetylase/ N -sulfotransferase (NDST-1) and high-endothelial cell GlcNAc-6-sulfotransferase (HEC-GlcNAc-6-ST). The assay proceeds by trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce3ef56f02d3183ef92a74ee9fd75ac
https://pubmed.ncbi.nlm.nih.gov/12202251
https://pubmed.ncbi.nlm.nih.gov/12202251