Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Dawn Chasse"'
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79228 (2013)
Gene expression signatures can predict the activation of oncogenic pathways and other phenotypes of interest via quantitative models that combine the expression levels of multiple genes. However, as the number of platforms to measure genome-wide gene
Externí odkaz:
https://doaj.org/article/fec19663fec04d6ca71663466d7dbbd7
Autor:
David T. Woodley, Mei Chen, Stanley M. Dunston, Jo-David Fine, Nancy A. Monteiro-Riviere, Dawn Chasse, Thierry Olivry, Aurea Pascal Tenorio
Publikováno v:
Veterinary dermatologyReferences. 9(1)
The classification of autoimmune blistering skin diseases is based on the skin antigen(s) targeted by pathogenic autoantibodies. In humans and dogs, there is increasing evidence that autoimmune subepidermal bullous diseases represent different nosolo
Autor:
Jacob C. Ruprecht, Amy L. McNulty, Katherine A. Glass, Benjamin Andress, J. Brice Weinberg, Farshid Guilak, Paolo Arrigoni, Dawn Chasse
Publikováno v:
Cartilage
Objectives The utilization of viral vectors to deliver genes of interest directly to meniscus cells and promote long-term modulation of gene expression may prove useful to enhance meniscus repair and regeneration. The objective of this study was to o
Autor:
Jennifer G. DeLuca, Edward D. Salmon, Xiaohu Wan, Kathleen R. Nevis, Karen T. Reidy, Jeanette Gowen Cook, Lynsie J.R. Sundin, Dawn Chasse, Dileep Varma, Srikripa Chandrasekaran
Publikováno v:
Nature cell biology
Cdt1, a protein critical for replication origin licensing in G1 phase is degraded during S phase but re-accumulates in G2 phase. We now demonstrate that human Cdt1 has a separable essential mitotic function. Cdt1 localizes to kinetochores during mito
Autor:
Johnathan M. Lancaster, Joseph R. Nevins, Quanli Wang, David H. Harpole, Anil Potti, Andrew Berchuck, Mike West, Dawn Chasse, John A. Olson, Holly K. Dressman, Andrea Bild, Mary Beth Joshi, Jeffrey T. Chang, Guang Yao, Jeffrey R. Marks
Publikováno v:
Nature. 439:353-357
The development of an oncogenic state is a complex process involving the accumulation of multiple independent mutations that lead to deregulation of cell signalling pathways central to the control of cell growth and cell fate. The ability to define c
Autor:
William C. Hahn, Rosalie C. Sears, Christopher M. Counter, Joseph R. Nevins, Shirish Shenolikar, Takafumi Uchida, Giovanni Ivaldi, Anthony R. Means, Melissa Cunningham, Elizabeth S. Yeh, Dawn Chasse, Teresa Monteith, P. Todd Stukenberg, Hugh Arnold
Publikováno v:
Nature Cell Biology. 6:308-318
The stability of c-Myc is regulated by multiple Ras effector pathways. Phosphorylation at Ser 62 stabilizes c-Myc, whereas subsequent phosphorylation at Thr 58 is required for its degradation. Here we show that Ser 62 is dephosphorylated by protein p
Autor:
Srikant Viswanadha, Daphne R. Friedman, Swaroop Vakkalanka, J. Brice Weinberg, Youwei Chen, Kumar V. Penmetsa, Dawn Chasse
Publikováno v:
Clinical Cancer Research. 21:A24-A24
Background: The PI3K pathway is a central pro-survival mechanism in chronic lymphocytic leukemia (CLL). While the delta isoform of PI3K is largely associated with B-cell signaling, gamma is involved in cytokine trafficking and modulation of the tumor