Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dawn C Harper"'
Autor:
Huijuan Bi, Jonas Tranell, Dawn C Harper, Weifeng Lin, Jingyi Li, Anders R Hellström, Mårten Larsson, Carl-Johan Rubin, Chao Wang, Shumaila Sayyab, Susanne Kerje, Bertrand Bed'hom, David Gourichon, Shosuke Ito, Kazumasa Wakamatsu, Michèle Tixier-Boichard, Michael S Marks, Daniel Globisch, Leif Andersson
Publikováno v:
PLoS Genetics, Vol 19, Iss 4, p e1010724 (2023)
The biochemical pathway regulating the synthesis of yellow/red pheomelanin is less well characterized than the synthesis of black/brown eumelanin. Inhibitor of gold (IG phenotype) is a plumage colour variant in chicken that provides an opportunity to
Externí odkaz:
https://doaj.org/article/26f9c941897443029cc17bdb2ccab876
Autor:
Emily E. Puckett, Isis S. Davis, Dawn C. Harper, Kazumasa Wakamatsu, Gopal Battu, Jerrold L. Belant, Dean E. Beyer, Colin Carpenter, Anthony P. Crupi, Maria Davidson, Christopher S. DePerno, Nicholas Forman, Nicholas L. Fowler, David L. Garshelis, Nicholas Gould, Kerry Gunther, Mark Haroldson, Shosuke Ito, David Kocka, Carl Lackey, Ryan Leahy, Caitlin Lee-Roney, Tania Lewis, Ashley Lutto, Kelly McGowan, Colleen Olfenbuttel, Mike Orlando, Alexander Platt, Matthew D. Pollard, Megan Ramaker, Heather Reich, Jaime L. Sajecki, Stephanie K. Sell, Jennifer Strules, Seth Thompson, Frank van Manen, Craig Whitman, Ryan Williamson, Frederic Winslow, Christopher B. Kaelin, Michael S. Marks, Gregory S. Barsh
SUMMARYColor variation is a frequent evolutionary substrate for camouflage in small mammals but the underlying genetics and evolutionary forces that drive color variation in natural populations of large mammals are mostly unexplained. The American bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ed3e0d9d12111244d78e5f44cad9d9
https://doi.org/10.1101/2022.08.12.503788
https://doi.org/10.1101/2022.08.12.503788
Autor:
David J. Owen, Dorothy C. Bennett, Yueyao Zhu, Graça Raposo-Benedetti, Elena V. Sviderskaya, Shanna L. Bowman, Dawn C. Harper, Michael S. Marks, Linh Le, Megan K. Dennis, Alexander C. Theos, Anand Sitaram
Publikováno v:
The Journal of Cell Biology
Bowman et al. show that in melanocytes, the vSNARE VAMP7 is sorted from endosomes into tubular membrane transport carriers bound for maturing melanosomes in a complex with the tSNARE syntaxin 13 via redundant recognition of each SNARE by an AP-3–BL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9aa7f4a23cc4c5be5194f97dee3e6f5
http://europepmc.org/articles/PMC8077166
http://europepmc.org/articles/PMC8077166
Autor:
Alexa Jaume, Shufang Meng, Michael S. Marks, Dawn C Harper, Susan H. Guttentag, Seunghyi Kook, Jude Franklin, Hayley A. Hanby
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46e5ac085d199771c8ad54e36e9e970c
https://doi.org/10.1096/fasebj.2019.33.1_supplement.658.1
https://doi.org/10.1096/fasebj.2019.33.1_supplement.658.1
Autor:
Cédric Delevoye, Silvia Benito-Martínez, Yueyao Zhu, Riddhi Atul Jani, Dawn C. Harper, Michael S. Marks
Publikováno v:
Journal of Investigative Dermatology
J Invest Dermatol
J Invest Dermatol
Pigmentation of the skin and hair represents the result of melanin biosynthesis within melanosomes of epidermal melanocytes, followed by the transfer of mature melanin granules to adjacent keratinocytes within the basal layer of the epidermis. Natura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac3af7977e865d0cb6ca36b2fbfdca7
https://doi.org/10.1016/j.jid.2019.12.002
https://doi.org/10.1016/j.jid.2019.12.002
Autor:
Dawn C. Harper, Liqing Xiao, Michael S. Marks, M. A. Kowalska, Mortimer Poncz, Michele P. Lambert, Ronghua Meng
Publikováno v:
Journal of Thrombosis and Haemostasis. 13:1888-1899
Summary Background Megakaryocytes express and store platelet factor 4 (PF4) in alpha granules. In vivo, PF4 is a clinically relevant, negative regulator of megakaryopoiesis and hematopoietic stem cell replication. These findings would suggest a regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa827ccb1594a7bfadc15cb2361361ec
https://doi.org/10.1111/jth.13069
https://doi.org/10.1111/jth.13069
Autor:
Brenda Watt, Dawn C. Harper, Karolina J. Janczura, Alexander C. Theos, Kathryn E. Herman, Michael S. Marks, Sarah C. Theos
Publikováno v:
Pigment Cell & Melanoma Research. 26:470-486
Proteolytic fragments of the pigment cell-specific glycoprotein, PMEL, form the amyloid fibrillar matrix underlying melanins in melanosomes. The fibrils form within multivesicular endosomes to which PMEL is selectively sorted and that serve as melano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4248a88dd1fdc247a05e750d865c77
https://doi.org/10.1111/pcmr.12084
https://doi.org/10.1111/pcmr.12084
Autor:
David C. Cowan, Subba Rao Gangi Setty, Steven T. Truschel, Sara D. Sackett, Danièle Tenza, Graça Raposo, Michael S. Marks, Penelope C. Thomas, Sabrina Simoes, Alexander C. Theos, Dawn C. Harper, Kathryn E. Herman
Publikováno v:
Traffic. 10:1318-1336
Melanosomes are lysosome-related organelles that coexist with lysosomes within melanocytes. The pathways by which melanosomal proteins are diverted from endocytic organelles toward melanosomes are incompletely defined. In melanocytes from mouse model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba7c5432deec9d0778aac1bf27a6047
https://doi.org/10.1111/j.1600-0854.2009.00955.x
https://doi.org/10.1111/j.1600-0854.2009.00955.x
Autor:
Concepción Lillo, Rivka A. Rachel, Tanja Diemer, David S. Williams, Janet R. Sparrow, Kathleen Boesze-Battaglia, Dawn C. Harper, Monika Damek-Poprawa, Vanda S. Lopes, Yalin Wu, Michael S. Marks
Publikováno v:
Journal of Biological Chemistry. 284:10877-10889
Melanoregulin (MREG), the product of the Mregdsu gene, is a small highly charged protein, hypothesized to play a role in organelle biogenesis due to its effect on pigmentation in dilute, ashen, and leaden mutant mice. Here we provide evidence that MR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b190a0de88fca812521abe65dc562cac
https://doi.org/10.1074/jbc.m808857200
https://doi.org/10.1074/jbc.m808857200
Autor:
Ilaria Palmisano, Esteban C. Dell'Angelica, Anand Sitaram, Rosanna Piccirillo, M. Vittoria Schiaffino, Dawn C. Harper, Michael S. Marks
Publikováno v:
Molecular Biology of the Cell. 20:1464-1477
Oculocutaneous albinism type 2 is caused by defects in the gene OCA2, encoding a pigment cell-specific, 12-transmembrane domain protein with homology to ion permeases. The function of the OCA2 protein remains unknown, and its subcellular localization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a5ccf24462111c4b4eaafcb6e9a69f
https://doi.org/10.1091/mbc.e08-07-0710
https://doi.org/10.1091/mbc.e08-07-0710