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pro vyhledávání: '"Dawn Bloomfield"'
Publikováno v:
British Journal of Pharmacy, Vol 8, Iss 2 (2023)
Enabling formulations are used by the pharmaceutical industry to help improve bioavailability of compounds with low solubility and permeability properties. Suspoemulsions are a combination strategy of using permeation enhancers in a lipid phase, with
Externí odkaz:
https://doaj.org/article/3a459323cdca459e8dad3ac69f077665
Autor:
Elisabetta Armani, Carmelida Capaldi, Valentina Bagnacani, Francesca Saccani, Giancarlo Aquino, Paola Puccini, Fabrizio Facchinetti, Cataldo Martucci, Nadia Moretto, Gino Villetti, Riccardo Patacchini, Maurizio Civelli, Chris Hurley, Andrew Jennings, Lilian Alcaraz, Dawn Bloomfield, Michael Briggs, Stephen Daly, Terry Panchal, Vince Russell, Sharon Wicks, Harry Finch, Mary Fitzgerald, Craig Fox, Maurizio Delcanale
Publikováno v:
Journal of Medicinal Chemistry. 65:7170-7192
The identification of novel inhaled p38α/β mitogen-activated protein kinases (MAPK) (MAPK14/11) inhibitors suitable for the treatment of pulmonary inflammatory conditions has been described. A rational drug design approach started from the identifi
Autor:
Angus Murray Macleod, L. Rebecca Fish, Monique Bodil Van Niel, Desmond O'Connor, Laura Catherine Cooper, Kevin J. Wilson, Dawn Bloomfield
Publikováno v:
ChemInform. 38
This report describes the effect of replacing the central basic amine present in many known 5-HT2A ligands with an aromatic residue. We targeted the isomeric phenethylpyridines 2 and 3 and these compounds proved to be excellent leads, possessing good