Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Dawn Belt, Davis"'
Autor:
Mark P. Keller, Kelly L. Hudkins, Anath Shalev, Sushant Bhatnagar, Melkam A. Kebede, Matthew J. Merrins, Dawn Belt Davis, Charles E. Alpers, Michelle E. Kimple, Alan D. Attie
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107036- (2023)
Summary: Human and mouse genetics have delivered numerous diabetogenic loci, but it is mainly through the use of animal models that the pathophysiological basis for their contribution to diabetes has been investigated. More than 20 years ago, we sere
Externí odkaz:
https://doaj.org/article/2a0d513bf5f14082a8f6d638bd1a6e49
Autor:
Rachel J. Fenske, Alicia M. Weeks, Michael Daniels, Randall Nall, Samantha Pabich, Allison L. Brill, Darby C. Peter, Margaret Punt, Elizabeth D. Cox, Dawn Belt Davis, Michelle E. Kimple
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1234 (2022)
Over half of patients with type 2 diabetes (T2D) are unable to achieve blood glucose targets despite therapeutic compliance, significantly increasing their risk of long-term complications. Discovering ways to identify and properly treat these individ
Externí odkaz:
https://doaj.org/article/08a0b32c202b471e9122aef220854e8f
Autor:
Dawn Belt Davis, Jad Khoraki, Martynas Ziemelis, Sirinart Sirinvaravong, Jee Young Han, Guilherme M. Campos
Publikováno v:
Molecular Metabolism, Vol 9, Iss , Pp 15-27 (2018)
Objective: Postprandial hypoglycemia is an infrequent but disabling complication of Roux-en-Y gastric bypass (RYGB) surgery. Controversy still exists as to whether the postprandial hyperinsulinemia observed is due to inherent changes in pancreatic β
Externí odkaz:
https://doaj.org/article/79d5a23cf99542f6b30a6b5f75d6b59c
Autor:
Grace H. Yang, Danielle A. Fontaine, Sukanya Lodh, Joseph T. Blumer, Avtar Roopra, Dawn Belt Davis
Publikováno v:
Metabolites, Vol 11, Iss 8, p 513 (2021)
Transcription factor 19 (TCF19) is a gene associated with type 1 diabetes (T1DM) and type 2 diabetes (T2DM) in genome-wide association studies. Prior studies have demonstrated that Tcf19 knockdown impairs β-cell proliferation and increases apoptosis
Externí odkaz:
https://doaj.org/article/2cd58b81ff084eec979f4d8c421ee859
Autor:
Mieke Baan, Steven J. Sacotte, Joseph T. Blumer, Jee Young Han, Heidi M. Umhoefer, Lucille E. Anzia, Rashaun A. Williams, Danielle A. Fontaine, Arnaldo H. de Souza, Carly R. Kibbe, Dawn Belt Davis, Jacob T. Bartosiak, Hung Tae Kim
Publikováno v:
Transl Res
Loss of functional pancreatic β-cell mass and increased β-cell apoptosis are fundamental to the pathophysiology of type 1 and type 2 diabetes. Pancreatic islet transplantation has the potential to cure type 1 diabetes but is often ineffective due t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a596c37f694ba992d718780a2af3a61
https://doi.org/10.1016/j.trsl.2021.10.005
https://doi.org/10.1016/j.trsl.2021.10.005
Autor:
Pradyut K Paul, Rahul Das, Travis J Drow, Arnaldo H de Souza, Appakalai N Balamurugan, Dawn Belt Davis, Jacques Galipeau
Publikováno v:
Stem Cells Translational Medicine. 11:630-643
Preserving islet health and function is critical during pretransplant culture to improve islet transplantation outcome and for ex vivo modeling of diabetes for pharmaceutical drug discovery. The limited islet engraftment potential is primarily attrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2ca71f1ec356d55b40624b75d6f725
https://doi.org/10.1093/stcltm/szac018
https://doi.org/10.1093/stcltm/szac018
Autor:
Rachel J, Fenske, Alicia M, Weeks, Michael, Daniels, Randall, Nall, Samantha, Pabich, Allison L, Brill, Darby C, Peter, Margaret, Punt, Elizabeth D, Cox, Dawn Belt, Davis, Michelle E, Kimple
Publikováno v:
Metabolites. 12(12)
Over half of patients with type 2 diabetes (T2D) are unable to achieve blood glucose targets despite therapeutic compliance, significantly increasing their risk of long-term complications. Discovering ways to identify and properly treat these individ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f69c0367bf472ec7661916bbcb9c7d65
https://pubmed.ncbi.nlm.nih.gov/36557272
https://pubmed.ncbi.nlm.nih.gov/36557272
Autor:
Lisa L. Abler, Sara A. Colopy, Zun-Yi Wang, Chad M. Vezina, Kimberly P. Keil Stietz, Mieke Baan, Dale E. Bjorling, Dawn Belt Davis, Peiqing Wang, Steven R Oakes, Faye A. Hartmann, Chelsea A. O’Driscoll, Jonathan N. Ouellette, Jyoti J. Watters, Matthew D Grimes, Michelle E. Kimple, Shannon J. Gallagher, Stephanie M Crader-Smith, Vatsal Mehta, Gordon S. Mitchell
Publikováno v:
Am J Physiol Renal Physiol
We used male BTBR mice carrying the Lep(ob) mutation, which are subject to severe and progressive obesity and diabetes beginning at 6 wk of age, to examine the influence of one specific manifestation of sleep apnea, intermittent hypoxia (IH), on male
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9efce25b4de66165d73977c3320095
https://doi.org/10.1152/ajprenal.00112.2021
https://doi.org/10.1152/ajprenal.00112.2021
Autor:
Austin Reuter, Samantha Pabich, Rachel J. Fenske, Alicia M Weeks, Dawn Belt Davis, Chinmai Patibandla, Elizabeth D. Cox, Harpreet K Sandhu, Randall Nall, Cecilia E Kaiser, Margaret Punt, Nathan A. Truchan, Allison L. Brill, Michelle E. Kimple, Darby C. Peter, Benjamin Wancewicz, Ying Ge, Jeffrey M. Harrington, Michael Daniels
Publikováno v:
ACS Pharmacol Transl Sci
We and others previously reported increased signaling through the Prostaglandin E3 Receptor (EP3), a G protein-coupled receptor (GPCR) for the arachidonic acid metabolite, prostaglandin E2 (PGE2), is associated with {beta}-cell dysfunction of type 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498dcd0cf9582fe7fd0a0ca4994b64f1
https://doi.org/10.1021/acsptsci.1c00045
https://doi.org/10.1021/acsptsci.1c00045
Autor:
Benjamin Wancewicz, Yanlong Zhu, Rachel J Fenske, Alicia M Weeks, Kent Wenger, Samantha Pabich, Michael Daniels, Margaret Punt, Randall Nall, Darby C Peter, Allan Brasier, Elizabeth D Cox, Dawn Belt Davis, Ying Ge, Michelle Kimple
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. :JPET-AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb50be1cfdc764a0d9eaf071c3a10829
https://doi.org/10.1124/jpet.122.001493
https://doi.org/10.1124/jpet.122.001493