Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Dawn A Lowe"'
Autor:
Pangdra Vang, Cory W Baumann, Rebecca Barok, Alexie A Larson, Brendan J Dougherty, Dawn A Lowe
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249472 (2021)
Female carriers of Duchenne muscular dystrophy (DMD) presenting with DMD symptomology similar to males with DMD, such as skeletal muscle weakness and cardiomyopathy, are termed manifesting carriers. There is phenotypic variability among manifesting c
Externí odkaz:
https://doaj.org/article/b9995376e8c345be8670ecdedfb50f70
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0199062 (2018)
The recent discovery that myosin has two distinct states in relaxed muscle-disordered relaxed (DRX) and super-relaxed (SRX)-provides another factor to consider in our fundamental understanding of the aging mechanism in skeletal muscle, since myosin i
Externí odkaz:
https://doaj.org/article/52c123ec02c049efb7562f71b34fa9a5
Autor:
Eija K Laakkonen, Janne Kulmala, Pauliina Aukee, Harto Hakonen, Urho M Kujala, Dawn A Lowe, Vuokko Kovanen, Tuija Tammelin, Sarianna Sipilä
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172054 (2017)
Physical activity improves health and may delay the onset of several chronic diseases. For women in particular, the rate of these diseases accelerates at middle age; therefore it is important to identify the determinants of health-enhancing physical
Externí odkaz:
https://doaj.org/article/81db5004fd7b4335a7df8bd4193d08ca
Autor:
Abhijit Dandapat, Benjamin J Perrin, Christine Cabelka, Maria Razzoli, James M Ervasti, Alessandro Bartolomucci, Dawn A Lowe, Michael Kyba
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151467 (2016)
Facioscapulohumeral muscular dystrophy (FSHD) is caused by mutations leading to ectopic expression of the transcription factor DUX4, and encompasses both muscle-related and non-muscle phenotypes. Mouse models bearing this gene represent valuable tool
Externí odkaz:
https://doaj.org/article/8b60ed8b718c45f291e3e516d4464c70
Autor:
Evelyne M Houang, Karen J Haman, Antonio Filareto, Rita C Perlingeiro, Frank S Bates, Dawn A Lowe, Joseph M Metzger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Duchenne muscular dystrophy (DMD) is a fatal disease of striated muscle deterioration. A unique therapeutic approach for DMD is the use of synthetic membrane stabilizers to protect the fragile dystrophic sarcolemma against contraction-induced mechani
Externí odkaz:
https://doaj.org/article/60d364671d0d4e19b34ee19796addcd7
Autor:
Susan A Novotny, Tara L Mader, Angela G Greising, Angela S Lin, Robert E Guldberg, Gordon L Warren, Dawn A Lowe
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104339 (2014)
The objective of the study was to determine if low intensity, high frequency vibration training impacted the musculoskeletal system in a mouse model of Duchenne muscular dystrophy, relative to healthy mice. Three-week old wildtype (n = 26) and mdx mi
Externí odkaz:
https://doaj.org/article/27be7dc7a52f4432869ab285ba7a0b11
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10164 (2010)
Estrogens are associated with the loss of skeletal muscle strength in women with age. Ovarian hormone removal by ovariectomy in mice leads to a loss of muscle strength, which is reversed with 17beta-estradiol replacement. Aging is also associated wit
Externí odkaz:
https://doaj.org/article/740b78ff5fec4771914d474094c1ee31
Autor:
Kevin J Sonnemann, Hanke Heun-Johnson, Amy J Turner, Kristen A Baltgalvis, Dawn A Lowe, James M Ervasti
Publikováno v:
PLoS Medicine, Vol 6, Iss 5, p e1000083 (2009)
The loss of dystrophin compromises muscle cell membrane stability and causes Duchenne muscular dystrophy and/or various forms of cardiomyopathy. Increased expression of the dystrophin homolog utrophin by gene delivery or pharmacologic up-regulation h
Externí odkaz:
https://doaj.org/article/4fdad23a597c44f7b801c8d249d2427a
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2419 (2008)
We previously documented a ten-fold increase in gamma(cyto)-actin expression in dystrophin-deficient skeletal muscle and hypothesized that increased gamma(cyto)-actin expression may participate in an adaptive cytoskeletal remodeling response. To expl
Externí odkaz:
https://doaj.org/article/084e035ca0974c39b533919e54933b2c
Autor:
Mina P. Peyton, Tzu-Yi Yang, LeeAnn Higgins, Todd W. Markowski, Cha Vue, Laurie L. Parker, Dawn A. Lowe
Publikováno v:
Physiological genomics. 54(11)
Background Phosphorylation is important in skeletal muscle development, growth, regeneration, and contractile function. Alterations in the skeletal muscle phosphoproteome due to aging have been reported in males; however, studies in females are lacki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a67bb7fe56b6313153b564fcc085299
https://pubmed.ncbi.nlm.nih.gov/36062884
https://pubmed.ncbi.nlm.nih.gov/36062884