Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Dawn, Chitty"'
Autor:
Carol Ann Keohane, Gloria Y. Kwei, Wei Tang, Susan A. Iliff, Adria Colletti, Vincent J. Colandrea, Frank S. Tang, Ann E. Weber, Randy R. Miller, Shuet-Hing Lee Chiu, William P. Feeney, Ralph A. Stearns, John R. Strauss, Dawn Chitty, Elizabeth M. Naylor, Robert J. Mathvink
Publikováno v:
Drug Metabolism and Disposition. 30:771-777
The pharmacokinetics and oral bioavailability of (R)-N-[4-[2-[[2-hydroxy-2-(pyridin-3-yl)ethyl]amino]ethyl]phenyl]-4-[4-[4-(trifluoromethylphenyl]thiazol-2-yl]benzenesulfonamide (1), a 3-pyridyl thiazole benzenesulfonamide beta3-adrenergic receptor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65069e1f2574839534bfaaec1aedc791
https://doi.org/10.1124/dmd.30.7.771
https://doi.org/10.1124/dmd.30.7.771
Autor:
Lawrence F. Colwell, William P. Feeney, Liping Deng, Michael J. Forrest, Randy R. Miller, Ralph A. Stearns, Ann E. Weber, Mari R. Candelore, Gary J Hom, D. E. Macintyre, Mathew J. Wyvratt, Dawn Chitty, Robert J. Mathvink, Tolman Js, Laurie Tota, Margaret A. Cascieri, M. H. Fisher
Publikováno v:
Journal of Medicinal Chemistry. 43:3832-3836
As part of our investigation into the development of orally bioavailable beta(3) adrenergic receptor agonists, we have identified a series of pyridylethanolamine analogues possessing a substituted thiazole benzenesulfonamide pharmacophore that are po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac50fd493c10b70259b4e092537228b
https://doi.org/10.1021/jm000286i
https://doi.org/10.1021/jm000286i
Autor:
D. Euan MacIntyre, Matthew J. Wyvratt, Ann E. Weber, Liping Deng, Michael J. Forrest, J.Samuel Tolman, Robert J. Mathvink, William P. Feeney, Margaret A. Cascieri, Laurie Tota, Lawrence F. Colwell, Dawn Chitty, Michael H. Fisher, Mari R. Candelore, Gary J Hom
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:1971-1973
A series of thiazole benzenesulfonamide-substituted 3-pyridylethanolamines was prepared and evaluated for their human beta3 adrenergic receptor agonist activity. Incorporation of aryl and heteroaryl substitution in the 4-position of the thiazole ring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec08eef98badb43cded82bcf04f02f82
https://doi.org/10.1016/s0960-894x(00)00390-5
https://doi.org/10.1016/s0960-894x(00)00390-5
Autor:
A, Stearns Ralph, R, Miller Randy, Wei, Tang, Y, Kwei Gloria, S, Tang Frank, J, Mathvink Robert, M, Naylor Elizabeth, Dawn, Chitty, J, Colandrea Vincent, E, Weber Ann, E, Colletti Adria, R, Strauss John, Ann, Keohane Carol, P, Feeney William, A, Iliff Susan, Lee, Chiu Shuet-Hing
Publikováno v:
Drug Metabolism and Disposition; July 2002, Vol. 30 Issue: 7 p771-7, 7p