Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Dawit KIDANE"'
Autor:
Zackary Shpilman, Dawit Kidane
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Head and neck squamous carcinoma (HNSCC) is caused by different exogenous risk factors including smoking cigarettes, alcohol consumption, and HPV infection. Base excision repair (BER) is the frontline to repair oxidative DNA damage, which
Externí odkaz:
https://doaj.org/article/d72dbaa640ac4a5cae2fa34259a9afa8
Autor:
Vidhyanand Mahase, Adebiyi Sobitan, Qiaobin Yao, Xinghua Shi, Hong Qin, Dawit Kidane, Qiyi Tang, Shaolei Teng
Publikováno v:
Viruses, Vol 16, Iss 7, p 1150 (2024)
The global effort to combat the COVID-19 pandemic faces ongoing uncertainty with the emergence of Variants of Concern featuring numerous mutations on the Spike (S) protein. In particular, the Omicron Variant is distinguished by 32 mutations, includin
Externí odkaz:
https://doaj.org/article/201fd6b406764c71a040e0e4d24bd729
Autor:
Achinto Saha, Shengyuan Zhao, Austin Kindall, Carly Wilder, Chelsea A. Friedman, Rachel Clark, George Georgiou, Everett Stone, Dawit Kidane, John DiGiovanni
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-17 (2023)
Abstract Background Prostate Cancer (PCa) represents one of the most commonly diagnosed neoplasms in men and is associated with significant morbidity and mortality. Therapy resistance and significant side effects of current treatment strategies indic
Externí odkaz:
https://doaj.org/article/3f4ed73c00f341e590363cee29c5b3b1
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Base excision repair (BER) has evolved to maintain the genomic integrity of DNA following endogenous and exogenous agent induced DNA base damage. In contrast, aberrant BER induces genomic instability, promotes malignant transformation and can even tr
Externí odkaz:
https://doaj.org/article/56074cafe5154dc99906152b3216da25
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Alpha-ketoglutarate-dependent dioxygenase (ALKBH) is a DNA repair gene involved in the repair of alkylating DNA damage. There are nine types of ALKBH (ALKBH1-8 and FTO) identified in humans. In particular, certain types of ALKBH enzymes are dioxygena
Externí odkaz:
https://doaj.org/article/e6c1bdef302649d5a0a584011d6fe2f8
Overexpression of associated with altered genome and poor survival in selected types of human cancer
Publikováno v:
Tumor Biology, Vol 42 (2020)
Base excision repair, which is initiated by the DNA N -glycosylase proteins, is the frontline for repairing potentially mutagenic DNA base damage. Several base excision repair genes are deregulated in cancer and affect cellular outcomes to chemothera
Externí odkaz:
https://doaj.org/article/8c495098d5d944c48c1cb3fd0f408670
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 557 (2022)
Innate immunity is critical for immediate recognition and elimination of invading pathogens or defense against cancer cell growth. Dysregulation of innate immune systems is associated with the pathogenesis of different types of inflammatory diseases,
Externí odkaz:
https://doaj.org/article/b4732b6fa8ed4c7fba2d38624bb25207
Publikováno v:
Insects, Vol 11, Iss 7, p 428 (2020)
Successful biological control of the whitefly Bemisia tabaci involves the mass rearing of biocontrol agents in large numbers for field release. Cold storage of the biocontrol agents is often necessary to provide a sufficient number of biocontrol agen
Externí odkaz:
https://doaj.org/article/7fd72883b0b344d3b31a14e1f344c3c4
Publikováno v:
European Journal of Entomology, Vol 112, Iss 3, Pp 460-469 (2015)
Encarsia sophia (Girault & Dodd) (Hymenoptera: Aphelinidae) is an important bio-control agent of Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae). Storage at low temperature is a valuable method used in the mass rearing of biological control agent
Externí odkaz:
https://doaj.org/article/a8eeebbdb5bd45659bf308ed06109ad7
Autor:
Alireza G. Senejani, Yanfeng Liu, Dawit Kidane, Stephen E. Maher, Caroline J. Zeiss, Hong-Jae Park, Michael Kashgarian, Jennifer M. McNiff, Daniel Zelterman, Alfred L.M. Bothwell, Joann B. Sweasy
Publikováno v:
Cell Reports, Vol 6, Iss 1, Pp 1-8 (2014)
A replication study of a previous genome-wide association study (GWAS) suggested that a SNP linked to the POLB gene is associated with systemic lupus erythematosus (SLE). This SNP is correlated with decreased expression of Pol β, a key enzyme in the
Externí odkaz:
https://doaj.org/article/d60217a0e3fe4edaa2240b7b757d30f8