Potent, Omicron-Neutralizing Antibodies Isolated From a Patient Vaccinated 6 Months Before Omicron Emergence

Autor: Kathryn Hastie, Xiaoying Yu, Fernanda Ana Sosa Batiz, Dawid Zyla, Stephanie S. Harkins, Chitra Hariharan, Hal Wasserman, Michelle Zandonatti, Robyn Miller, Erin Maule, Kenneth Kim, Kristen Valentine, Sujan Shresta, Erica Ollmann Saphire

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d86c8ebeaa3efbdc23911326c9ad539
https://doi.org/10.2139/ssrn.4327436

Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody

Autor: Heather M. Callaway, Dawid Zyla, Florence Larrous, Guilherme Dias de Melo, Kathryn M. Hastie, Ruben Diaz Avalos, Alyssa Agarwal, Davide Corti, Hervé Bourhy, Erica Ollmann Saphire

Publikováno v: Science Advances
Science Advances, 2022, 8 (24), ⟨10.1126/sciadv.abp9151⟩

International audience; Rabies infection is nearly 100% lethal if untreated and kills more than 50,000 people annually, many of them children. Existing rabies vaccines target the rabies virus glycoprotein (RABV-G) but generate short-lived immune resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c75fe13c01d268eac99ce6c01b18924
https://doi.org/10.1126/sciadv.abp9151

Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA

Autor: Rudi Glockshuber, Blanca Echeverria, Dawid Zyla

Publikováno v: J Biol Chem
Journal of Biological Chemistry, 295 (35)

FimA is the main structural subunit of adhesive type 1 pili from uropathogenic Escherichia coli strains. Up to 3000 copies of FimA assemble to the helical pilus rod through a mechanism termed donor strand complementation, in which the incomplete immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d62829ba408ca57025f7b6f2a7797d1
https://doi.org/10.1074/jbc.ra120.014324

Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study

Autor: Yanan Lu, Timothy C. Germann, Adrian Enriquez, Ruben Diaz Avalos, Marit J. van Gils, Ana G. Lujan Hernandez, Yoann Aldon, Guojun Lang, Mohammad M. Sajadi, Elizabeth Feeney, John Ingraham, Georgia D. Tomaras, Milite Abraha, Junli Liu, Jacob Glanville, S. Moses Dennison, Minsoo Kim, Erica Ollmann Saphire, Sawsan Youssef, Ross S. Federman, Gillian Q. Horn, Bingqing Shen, Sean Hui, Anne L. Palser, Joseph M. Fernandez, Gevorg Grigoryan, Vamseedhar Rayaprolu, David D. Ho, Jieyun Yin, Sharon L. Schendel, Jian Yu, Haoyang Li, Shelly J. Krebs, Qian Zhang, Ronald R. Cobb, Colin Mann, Eduardo Olmedillas, Rogier W. Sanders, Robin Green, Hyeong Mi Kim, Tierra Buck, Dawid Zyla, Hanif Ali, Paul Kellam, Terence H. Rabbitts, Diptiben V. Parekh, Anna J. MacCamy, Cheolmin Kim, Kuan-Ying A. Huang, Milan T. Tomic, Andrew T. McGuire, Tom Z. Yuan, Chitra Hariharan, Zahra Rikhtegaran Tehrani, Bjoern Peters, Xiaoying Yu, Sooyoung Lee, CoVIC-DB team, Kan Li, Leonidas Stamatatos, Cheuk Lun Leung, Chao Kong, Michelle Zandonatti, Fei Lan, Yongcong Tan, Aaron K. Sato, Kathryn M. Hastie, Liang Schweizer, Sanja Aracic, Jonne L. Snitselaar, Weidong Jiang, Kelly Shaffer, Jimin Seo, Daniel Bedinger

Publikováno v: Science, 374(6566), 478-472. American Association for the Advancement of Science
Science

Antibody-based therapeutics and vaccines are essential to combat COVID-19 morbidity and mortality after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Multiple mutations in SARS-CoV-2 that could impair antibody defenses propa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d77d508652c2afc125beaacf08e3394
https://pure.amc.nl/en/publications/defining-variantresistant-epitopes-targeted-by-sarscov2-antibodies(74d2b427-bf9c-4668-a36e-35475cd84986).html

Biomolecular solid-state NMR spectroscopy at 1200 MHz : the gain in resolution

Autor: Anja Böckmann, Lauriane Lecoq, Riccardo Cadalbert, Andreas Hunkeler, Morgane Callon, Matías Chávez, Matthias Ernst, Beat H. Meier, Marco E. Weber, Thomas Wiegand, Alexander A. Malär, Marie-Laure Fogeron, Dawid Zyla, Michael Nassal, Alexander Däpp, Rajdeep Deb, Stefanie Jonas, Rudolf Glockshuber, Johannes Zehnder, Anahit Torosyan, Sara Pfister, Václav Římal

Publikováno v: Journal of biomolecular NMR 75(6/7), 255-272 (2021). doi:10.1007/s10858-021-00373-x
Journal of Biomolecular NMR, 75 (6)
Journal of Biomolecular NMR
Journal of Biomolecular NMR, Springer Verlag, 2021, 75, pp.255-272. ⟨10.1007/s10858-021-00373-x⟩
Journal of Biomolecular Nmr
Journal of Biomolecular NMR, Springer Verlag, 2021, 75 (6-7), pp.255-272. ⟨10.1007/s10858-021-00373-x⟩
Journal of biomolecular NMR

Journal of biomolecular NMR 75(6/7), 255-272 (2021). doi:10.1007/s10858-021-00373-x
Published by Springer Science + Business Media B.V, Dordrecht [u.a.]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d9ceebb70648ca080d4b72a4af90bf