Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Dawen Kou"'
Autor:
Wei Jia, Phillip D. Yawman, Keyur M. Pandya, Kellie Sluga, Tania Ng, Dawen Kou, Karthik Nagapudi, Paul E. Luner, Aiden Zhu, Shawn Zhang, Hao Helen Hou
Publikováno v:
Pharmaceutical Research. 39:3137-3154
The purpose of this work is to evaluate the interrelationship of microstructure, properties, and dissolution performance for amorphous solid dispersions (ASDs) prepared using different methods.ASD of GDC-0810 (50% w/w) with HPMC-AS was prepared using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e731878341a27a4bc00f86ef93b51c5b
https://doi.org/10.1007/s11095-022-03308-9
https://doi.org/10.1007/s11095-022-03308-9
Autor:
James Mann, Andre Hermans, Nathan Contrella, Beverly Nickerson, Carrie A. Coutant, Christian Jede, Shangming Kao, Dawen Kou, Emmanuel Scheubel, Fredrik Winge, Johanna Milsmann, Martin Mueller-Zsigmondy, Nikolay Zaborenko
Publikováno v:
Dissolution Technologies. 29:190-203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7320b3f51c8b611f987792d4968950c3
https://doi.org/10.14227/dt290422p190
https://doi.org/10.14227/dt290422p190
Autor:
Davide Vecchietti, Akira Nishio, Yuichiro Fujita, Takeshi Yoshida, Toshinobu Yanagisawa, Dawen Kou
Publikováno v:
Journal of Chromatography A. 1678:463364
This paper systematically investigated and reported for the first time the identification and quantification of co-eluting impurities as low as 0.05 area% by PDA with i-PDeA II deconvolution software in the LabSolutions Chromatographic Data System (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ef2cfd5f010ea1c1966ce194bf042d1
https://doi.org/10.1016/j.chroma.2022.463364
https://doi.org/10.1016/j.chroma.2022.463364
Autor:
Dawen Kou, Larry Wigman, Chen Zhang, Tania Ng, Matthew R. Durk, Hiuwing Yiu, Leslie W. Chinn, Matthew Janson, Joseph W. Lubach, Peter Yehl, Helen Winter, Chen Mao
Publikováno v:
Molecular Pharmaceutics. 15:1607-1617
In this study, a multipronged approach of in vitro experiments, in silico simulations, and in vivo studies was developed to evaluate the dissolution, supersaturation, precipitation, and absorption of three formulations of Compound-A, a BCS class 2 we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089b0b2c7a67f49cbf57aa2ec0c18685
https://doi.org/10.1021/acs.molpharmaceut.7b01143
https://doi.org/10.1021/acs.molpharmaceut.7b01143
Autor:
Preeti Patel, Chen Mao, Yannick Fischer, Hiuwing Yiu, Peter Yehl, Leslie W. Chinn, Larry Wigman, Sudharsan Dwaraknath, Daniel Nguyen, Dawen Kou, Tania Ng, Myeonghui Kim, Helen Winter, Matthew R. Durk
Publikováno v:
Molecular pharmaceutics. 14(10)
In this study, two dissolution models were developed to achieve in vitro-in vivo relationship for immediate release formulations of Compound-A, a poorly soluble weak base with pH-dependent solubility and low bioavailability in hypochlorhydric and ach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdeaa9167d5a60b24853eae86478400a
https://pubmed.ncbi.nlm.nih.gov/28834434
https://pubmed.ncbi.nlm.nih.gov/28834434
Publikováno v:
Charged Aerosol Detection for Liquid Chromatography and Related Separation Techniques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d37b73b2cae8b64603d9de088a4cacad
https://doi.org/10.1002/9781119390725.ch8
https://doi.org/10.1002/9781119390725.ch8
Publikováno v:
Journal of Chromatography A. 1216:5424-5428
A technique of using size exclusion chromatography (SEC) with the Corona charged aerosol detector (CAD) was developed and evaluated in comparison with refractive index (RI) and evaporative light scattering detection (ELSD) for fast screening of polye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad99fb977c7a809d942f7277c7eabb8c
https://doi.org/10.1016/j.chroma.2009.05.043
https://doi.org/10.1016/j.chroma.2009.05.043
Publikováno v:
Journal of Chromatography A. 1055:63-69
Supported liquid membrane microextraction (SLMME) with high-performance liquid chromatography (HPLC)-UV detection has been developed for the extraction, preconcentration, and determination of all the nine haloacetic acids (HAAs) in water. The HAAs ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04e609fb09705a17a3c89674d5ff3b0
https://doi.org/10.1016/j.chroma.2004.09.022
https://doi.org/10.1016/j.chroma.2004.09.022
Publikováno v:
Sample Preparation of Pharmaceutical Dosage Forms ISBN: 9781441996305
The analytical procedure describes all the steps and details associated with performing an analysis. The validation process establishes the performance characteristics of the analytical procedure to meet the output requirements for the intended analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4bddf789115789ef5f9b422a1b7337a
https://doi.org/10.1007/978-1-4419-9631-2_10
https://doi.org/10.1007/978-1-4419-9631-2_10
Publikováno v:
Sample Preparation of Pharmaceutical Dosage Forms ISBN: 9781441996305
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14810c12836428e1de436a906540749c
https://doi.org/10.1007/978-1-4419-9631-2_2
https://doi.org/10.1007/978-1-4419-9631-2_2