Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Dawen Cai"'
Autor:
Bárbara Adem, Nuno Bastos, Carolina F. Ruivo, Sara Sousa-Alves, Carolina Dias, Patrícia F. Vieira, Inês A. Batista, Bruno Cavadas, Dieter Saur, José C. Machado, Dawen Cai, Sonia A. Melo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC), a lethal disease, requires a grasp of its biology for effective therapies. Exosomes, implicated in cancer, are poorly understood in living systems. Here we use the genetically engineered mouse model (
Externí odkaz:
https://doaj.org/article/bc7d9ee1ccd04333abccf2b19c10a836
Autor:
Fred Y. Shen, Margaret M. Harrington, Logan A. Walker, Hon Pong Jimmy Cheng, Edward S. Boyden, Dawen Cai
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Mapping neuroanatomy is a foundational goal of connectomics, and the gold standard method is electron microscopy as light microscopy lacks nanoscale resolution. Here the authors develop a strategy using multicolor genetic labeling (Brainbow) and expa
Externí odkaz:
https://doaj.org/article/0eb3bbd03f284394bd5506dd6b183bad
Autor:
Ye Li, Logan A. Walker, Yimeng Zhao, Erica M. Edwards, Nigel S. Michki, Hon Pong Jimmy Cheng, Marya Ghazzi, Tiffany Y. Chen, Maggie Chen, Douglas H. Roossien, Dawen Cai
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Identifying the cellular origins and mapping the dendritic and axonal arbors of neurons have been century old quests to understand the heterogeneity among these brain cells. Current Brainbow based transgenic animals take the advantage of multispectra
Externí odkaz:
https://doaj.org/article/849b373750cb42159ca6d3ed503409ba
Autor:
Shuvasree SenGupta, Lauren E. Hein, Yang Xu, Jason Zhang, Jamie R. Konwerski, Ye Li, Craig Johnson, Dawen Cai, Janet L. Smith, Carole A. Parent
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tumor associated neutrophils (TANs) are frequently detected in triple-negative breast cancer (TNBC). Recent studies also reveal the importance of neutrophils in promoting tumor progression and metastasis during breast cancer. However, the mechanisms
Externí odkaz:
https://doaj.org/article/b4bdece98600497ea21b6e8993c8645f
Autor:
Macy W. Veling, Ye Li, Mike T. Veling, Christopher Litts, Nigel Michki, Hao Liu, Bing Ye, Dawen Cai
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3303-3312.e3 (2019)
Summary: Elucidating cell lineages provides crucial understanding of development. Recently developed sequencing-based techniques enhance the scale of lineage tracing but eliminate the spatial information offered by conventional approaches. Multi-spec
Externí odkaz:
https://doaj.org/article/745717ee4e744afbb19f82c25a03e00a
Publikováno v:
PLoS Biology, Vol 7, Iss 10, p e1000216 (2009)
Cells generate diverse microtubule populations by polymerization of a common alpha/beta-tubulin building block. How microtubule associated proteins translate microtubule heterogeneity into specific cellular functions is not clear. We evaluated the ab
Externí odkaz:
https://doaj.org/article/57e81366c94e4c0db3c14a84ce39b552
Publikováno v:
PLoS Pathogens, Vol 5, Iss 6, p e1000465 (2009)
The mechanisms by which receptors guide intracellular virus transport are poorly characterized. The murine polyomavirus (Py) binds to the lipid receptor ganglioside GD1a and traffics to the endoplasmic reticulum (ER) where it enters the cytosol and t
Externí odkaz:
https://doaj.org/article/01529c43d05943af82ac3cdb72d437d0
Autor:
Jennetta W Hammond, Dawen Cai, T Lynne Blasius, Zhe Li, Yuyang Jiang, Gloria T Jih, Edgar Meyhofer, Kristen J Verhey
Publikováno v:
PLoS Biology, Vol 7, Iss 3, p e72 (2009)
Kinesin-3 motors drive the transport of synaptic vesicles and other membrane-bound organelles in neuronal cells. In the absence of cargo, kinesin motors are kept inactive to prevent motility and ATP hydrolysis. Current models state that the Kinesin-3
Externí odkaz:
https://doaj.org/article/9a746ddfe70b49048266402d4ad8656d
Autor:
Logan A. Walker, Jennifer S. Williams, Ye Li, Douglas H. Roossien, Wei Jie Lee, Nigel S. Michki, Dawen Cai
Publikováno v:
Neuroinformatics
The study of neuron morphology requires robust and comprehensive methods to quantify the differences between neurons of different subtypes and animal species. Several software packages have been developed for the analysis of neuron tracing results st
Autor:
Maria Ahmed, Adithya E. Rajagopalan, Yijie Pan, Ye Li, Donnell L. Williams, Erik A. Pedersen, Manav Thakral, Angelica Previero, Kari C. Close, Christina P. Christoforou, Dawen Cai, Glenn C. Turner, E. Josephine Clowney
Publikováno v:
bioRxiv
Animals can discriminate myriad sensory stimuli but can also generalize from learned experience. You can probably distinguish the favorite teas of your colleagues while still recognizing that all tea pales in comparison to coffee. Tradeoffs between d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fb0445a19776eba942a04f5fd6d6f6
https://europepmc.org/articles/PMC9900841/
https://europepmc.org/articles/PMC9900841/