Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Dawei Zou"'
Autor:
Hui Yan, Yulin Dai, Xiaolong Zhang, Hedong Zhang, Xiang Xiao, Jinfei Fu, Dawei Zou, Anze Yu, Tao Jiang, Xian C. Li, Zhongming Zhao, Wenhao Chen
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108087- (2023)
Summary: Understanding the factors that regulate T cell infiltration and functional states in solid tumors is crucial for advancing cancer immunotherapies. Here, we discovered that the expression of interferon regulatory factor 4 (IRF4) was a critica
Externí odkaz:
https://doaj.org/article/4e411c5a139a4a2c863644684a5f2d6f
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Immunotherapy has limited effectiveness in ovarian cancer (OC) patients, highlighting the need for reliable biomarkers to predict the effectiveness of these treatments. The C-X-C motif chemokine ligands (CXCLs) have been shown to be assoc
Externí odkaz:
https://doaj.org/article/4c0b1c343dcf486182fbded44cb7cdae
Autor:
Anze Yu, Jinfei Fu, Zheng Yin, Hui Yan, Xiang Xiao, Dawei Zou, Xiaolong Zhang, Xiongbing Zu, Xian C. Li, Wenhao Chen
Publikováno v:
Research, Vol 6 (2023)
T-cell-based immunotherapy is gaining momentum in cancer treatment; however, our comprehension of the transcriptional regulation governing T cell antitumor activity remains constrained. The objective of this study was to explore the function of inter
Externí odkaz:
https://doaj.org/article/75926a2c40994be59d960bc5ccbae9c8
Autor:
Linhe Wang, Jie Li, Shuai He, Yang Liu, Haitian Chen, Shujiao He, Meixian Yin, Dawei Zou, Shirui Chen, Tao Luo, Xinyu Yu, Xuesi Wan, Shunwei Huang, Zhiyong Guo, Xiaoshun He
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-17 (2021)
Abstract Ischemia–reperfusion injury (IRI) remains the major reason for impaired donor graft function and increased mortality post-liver transplantation. The mechanism of IRI involves multiple pathophysiological processes and numerous types of cell
Externí odkaz:
https://doaj.org/article/86ba605e8dd14dd6a0969bc23f2cdb3f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Allogeneic CD8+ T cells are prominently involved in allograft rejection, but how their effector differentiation and function are regulated at a transcriptional level is not fully understood. Herein, we identified the basic leucine zipper ATF-like tra
Externí odkaz:
https://doaj.org/article/e904cea255ec4ebba1591b5c5673d966
Autor:
Jiayi Xu, Xiaomeng Shan, Chunwei Chen, Yanbin Gao, Dawei Zou, Xiaolei Wang, Tao Wang, Yimin Shi
Publikováno v:
Journal of Diabetes Research, Vol 2022 (2022)
Diabetic nephropathy (DN) is a microvascular complication of diabetes mellitus (DM) and the most common cause of death in diabetic patients. DN progression is associated with podocyte damage due to reduced autophagy caused by mTORC1 activation. Tangs
Externí odkaz:
https://doaj.org/article/a3a3d1634cdd4f448700b68640d8bb43
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T cell stemness and exhaustion coexist as two key contrasting phenomena during chronic antigen stimulation, such as infection, transplant, cancer, and autoimmunity. T cell exhaustion refers to the progressive loss of effector function caused by chron
Externí odkaz:
https://doaj.org/article/4b738df90b3e4bb3b05d77928270a7c1
Autor:
Bo Zeng, Xin Zhang, Jingling Zhao, Zhewei Wei, Haoshuai Zhu, Minyi Fu, Dawei Zou, Yanfen Feng, Honghe Luo, Yiyan Lei
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is the major subtype of esophageal cancer with high aggressiveness and poor prognosis. There is an urgent need for understanding the molecular mechanism underlying the development and prog
Externí odkaz:
https://doaj.org/article/6291a4c5e02940fba56ef9e78421a493
METTL3 inhibition reduces N 6 ‐methyladenosine levels and prevents allogeneic CD4 + T‐cell responses
Publikováno v:
Immunology & Cell Biology. 100:718-730
Publikováno v:
Current Transplantation Reports.