Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Dawang Zhou"'
Autor:
Peisi Li, Dawang Zhou, Dongwen Chen, Yikan Cheng, Yuan Chen, Zhensen Lin, Xi Zhang, Zhihong Huang, Jiawei Cai, Wenfeng Huang, Yanyun Lin, Haoxian Ke, Jiahui Long, Yifeng Zou, Shubiao Ye, Ping Lan
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-19 (2023)
Abstract Background A large proportion of the patients with cancer do not respond to immunotherapies. Recent studies suggested an important role for tumor-infiltrating cytotoxic T lymphocytes (CTL) in enhancing response to immunotherapy. Here, we aim
Externí odkaz:
https://doaj.org/article/e312aa40d5b44aef8698e94d47b5d73e
SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling
Autor:
Dongxue Su, Yuxi Li, Weiji Zhang, Huan Gao, Yao Cheng, Yongqiang Hou, Junhong Li, Yi Ye, Zhangjian Lai, Zhe Li, Haitao Huang, Jiaxin Li, Jinhuan Li, Mengyu Cheng, Cheng Nian, Na Wu, Zhien Zhou, Yunzhi Xing, Yu Zhao, He Liu, Jiayu Tang, Qinghua Chen, Lixin Hong, Wengang Li, Zhihai Peng, Bin Zhao, Randy L. Johnson, Pingguo Liu, Wanjin Hong, Lanfen Chen, Dawang Zhou
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
The loss of contact inhibition is a key step during carcinogenesis. The Hippo–Yes-associated protein (Hippo/YAP) pathway is an important regulator of cell growth in a cell density–dependent manner. However, how Hippo signaling senses cell density
Externí odkaz:
https://doaj.org/article/10851ccf1c0d4b83bc5cb1bf57cbefc0
Autor:
Liangkui Li, Haoyu Zhou, Jinhui Wang, Jiaxin Li, Xuchao Lyu, Wenshan Wang, Chengting Luo, He Huang, Dawang Zhou, Xiaowei Chen, Li Xu, Peng Li
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 10, Pp 100440- (2023)
Neonates strive to acquire energy when the continuous transplacental nutrient supply ceases at birth, whereas milk consumption takes hours to start. Using murine models, we report the metabolic switches in the first days of life, with an unexpected d
Externí odkaz:
https://doaj.org/article/a4926560d911496ea134edb0b826f0e6
Autor:
Xinyue Lv, Peipei Ding, Luying Li, Ling Li, Danlei Zhou, Xiaochao Wang, Jianfeng Chen, Wei Zhang, Qi Wang, Tian Liao, Wenyu Wen, Dawang Zhou, Qing-Hai Ji, Xianghuo He, Qun-Ying Lei, Weiguo Hu
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101766- (2023)
Sufficient evidence has linked many different types of cancers and T2D through shared risk factors; however, the underlying mechanisms are not fully understood. α-Hydroxybutyrate (α-HB), a byproduct metabolite increased in diabetes and cancer, incl
Externí odkaz:
https://doaj.org/article/cacb6d4737814e1abb411fe1c2ef9871
Autor:
Cong Liu, Dawang Zhou, Qiang Zhang, Hongyan Wei, Yuanzheng Lu, Bo Li, Haohong Zhan, Jingge Cheng, Chuyue Wang, Yilin Yang, Shuhao Li, Chunlin Hu, Xiaoxing Liao
Publikováno v:
PeerJ, Vol 11, p e15841 (2023)
Background Adverse left ventricular remodeling after myocardial infarction (MI) compromises cardiac function and increases heart failure risk. Until now, comprehension of the role transcription factor EB (TFEB) plays after MI is limited. Objectives T
Externí odkaz:
https://doaj.org/article/515fdc95ad3649589424c347c39f33a1
Autor:
Chenyu Zhang, Haohong Zhan, Dawang Zhou, Tian Li, Qiang Zhang, Cong Liu, Hongyan Wei, Chunlin Hu
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Objective Cardiac arrest (CA) is caused by a nonshockable rhythm with a low success rate of return of spontaneous circulation (ROSC) and a poor prognosis. This study intended to establish a nonshockable rhythm CA model caused by asphyxia. Ma
Externí odkaz:
https://doaj.org/article/0a0c94304e16406b883e85e3cf33be0a
Autor:
Yuanpei Li, Xiaoniu He, Xiao Lu, Zhicheng Gong, Qing Li, Lei Zhang, Ronghui Yang, Chengyi Wu, Jialiang Huang, Jiancheng Ding, Yaohui He, Wen Liu, Ceshi Chen, Bin Cao, Dawang Zhou, Yufeng Shi, Juxiang Chen, Chuangui Wang, Shengping Zhang, Jian Zhang, Jing Ye, Han You
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
METTL3 catalyzes mRNA m6A deposition. The authors identify an acetylation-mediated regulation of METTL3 subcellular localization and compartment-specific functions, a process that is fine-tuned by anti-inflammatory and pro-inflammatory signals, which
Externí odkaz:
https://doaj.org/article/6d9c4809d19a4cadb353a7ca7474fad8
Autor:
Shuaifeng Li, Shixun Han, Qi Zhang, Yibing Zhu, Haitao Zhang, Junli Wang, Yang Zhao, Jianhui Zhao, Lin Su, Li Li, Dawang Zhou, Cunqi Ye, Xin-Hua Feng, Tingbo Liang, Bin Zhao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Fragmented mitochondria are a frequent hallmark of cancer, but the cause and consequence are less clear. The authors demonstrate that elevated FUNDC2 causes mitochondrial fragmentation through inhibition of MFN1 in hepatocellular carcinoma and that k
Externí odkaz:
https://doaj.org/article/5ec2dd2560f7427f9e3b510ca7292cea
Autor:
Jing Geng, Yiran Shi, Jinjia Zhang, Bingying Yang, Ping Wang, Weihong Yuan, Hao Zhao, Junhong Li, Funiu Qin, Lixin Hong, Changchuan Xie, Xianming Deng, Yujie Sun, Congying Wu, Lanfen Chen, Dawang Zhou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Innate immune cells respond to a number of environmental cues including TLR signalling. Here the authors implicate mechanical sensor Piezo1 in the TLR4 mediated host response to bacterial infection and implicate it in the enhancement of macrophage me
Externí odkaz:
https://doaj.org/article/75c48bfb0aaf48df8cd5e8d33bcbb665
Autor:
Yue Lu, Zhenzhen Fan, Su‐Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xuehui Hong, Ting Zhang, Li Li, Xihuan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Baoding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Siyang Song, Xin Huang, Qiao Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Cai‐Hong Yun, Liang Chen, Xianming Deng
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 1, Pp n/a-n/a (2022)
Abstract More than 60% of nonsmall cell lung cancer (NSCLC) patients show a positive response to the first ALK inhibitor, crizotinib, which has been used as the standard treatment for newly diagnosed patients with ALK rearrangement. However, most pat
Externí odkaz:
https://doaj.org/article/c6601c62cfee423f8b9920da0e450eea