Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Daw-Yang Hwang"'
Autor:
Chan-Chuan Liu, Wen-Bin Yang, Chia-Hung Chien, Cheng-Lin Wu, Jian-Ying Chuang, Pin-Yuan Chen, Jui-Mei Chu, Siao Muk Cheng, Li-Ying Qiu, Yung-Chieh Chang, Daw-Yang Hwang, Chih-Yuan Huang, Jung-Shun Lee, Kwang-Yu Chang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-12 (2024)
Abstract The interaction between glioblastoma cells and glioblastoma-associated macrophages (GAMs) influences the immunosuppressive tumor microenvironment, leading to ineffective immunotherapies. We hypothesized that disrupting the communication betw
Externí odkaz:
https://doaj.org/article/8941b26983c14c8cb27f8a700e1b0555
Autor:
Lee‐Moay Lim, Yi‐Chen Lee, Ting‐Wei Lin, Zi‐Xuan Hong, Wei‐Chi Hsu, Hung‐Lung Ke, Daw‐Yang Hwang, Wen‐Yu Chung, Wei‐Ming Li, Hui‐Hui Lin, Hung‐Tien Kuo, A‐Mei Huang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 5, Pp 445-455 (2024)
Abstract Neurotrophic receptor tyrosine kinase 3 (NTRK3) has pleiotropic functions: it acts not only as an oncogene in breast and gastric cancers but also as a dependence receptor in tumor suppressor genes in colon cancer and neuroblastomas. However,
Externí odkaz:
https://doaj.org/article/9e5d7c95c6ce4eaba4f6fa0ce58da1f1
Autor:
Siao Muk Cheng, Yung-Yeh Su, Nai-Jung Chiang, Chih-Jung Wang, Ying-Jui Chao, Chien-Jui Huang, Hui-Jen Tsai, Shang-Hung Chen, Chi-Yen Chang, Chia-Rung Tsai, Yi-Jie Li, Chia-Jui Yen, Shih-Chang Chuang, Jeffrey Shu-Ming Chang, Yan-Shen Shan, Daw-Yang Hwang, Li-Tzong Chen
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-14 (2024)
Abstract Background Cancer susceptibility germline mutations are associated with pancreatic ductal adenocarcinoma (PDAC). However, the hereditary status of PDAC and its impact on survival is largely unknown in the Asian population. Methods Exome sequ
Externí odkaz:
https://doaj.org/article/df7f60f9ec36445e8735f2495587c8d3
Publikováno v:
Kidney Medicine, Vol 6, Iss 5, Pp 100815- (2024)
Alport syndrome (AS) is a progressive hereditary kidney disease characterized by hematuria, proteinuria, and progressive kidney dysfunction accompanied by sensorineural hearing loss and ocular abnormalities. Pathogenic COL4A3-5 variants can result in
Externí odkaz:
https://doaj.org/article/9b76a6ee187e42edb3314fdfc9715e6f
Autor:
Chi-Che Hsieh, Yue-Chiu Su, Kuan-Ying Jiang, Takamichi Ito, Ting-Wei Li, Yumiko Kaku-Ito, Shih-Tsung Cheng, Li-Tzong Chen, Daw-Yang Hwang, Che-Hung Shen
Publikováno v:
Journal of Advanced Research, Vol 43, Iss , Pp 45-57 (2023)
Introduction: Acral melanoma is a predominant and aggressive subtype of melanoma in non-Caucasian populations. There is a lack of genotype-driven therapies for over 50% of patients. TRPM1 (transient receptor potential melastatin 1), a nonspecific cat
Externí odkaz:
https://doaj.org/article/45f85d2e01b84468a49f262c71d68593
Autor:
Lee-Moay Lim, Wen-Yu Chung, Daw-Yang Hwang, Chih-Chuan Yu, Hung-Lung Ke, Peir-In Liang, Ting-Wei Lin, Siao Muk Cheng, A-Mei Huang, Hung-Tien Kuo
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Kidney transplantation is a lifesaving option for patients with end-stage kidney disease. In Taiwan, urothelial carcinoma (UC) is the most common de novo cancer after kidney transplantation (KT). UC has a greater degree of molecular heteroge
Externí odkaz:
https://doaj.org/article/ae7e7039684448ee8248bbf8416ab6da
Autor:
Chih-Chuan Yu, An-Fu Lee, Stefen Kohl, Ming-Yen Lin, Siao Muk Cheng, Chi-Chih Hung, Jer-Ming Chang, Yi-Wen Chiu, Shang-Jyh Hwang, Edgar A. Otto, Friedhelm Hildebrandt, Taiwan PKD Consortium, Daw-Yang Hwang
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Autosomal Dominant polycystic kidney disease (ADPKD) is the most common inherited adult kidney disease. Although ADPKD is primarily caused by PKD1 and PKD2, the identification of several novel causative genes in recent years has revealed mor
Externí odkaz:
https://doaj.org/article/a482c7e00eb04f74925297dd7ae068a0
Autor:
Chia-Hung Chien, Wen-Bin Yang, Jian-Ying Chuang, Jung-Shun Lee, Wei-An Liao, Chih-Yuan Huang, Pin-Yuan Chen, An-Chih Wu, Shun-Tai Yang, Chien-Cheng Lai, Pei-I Chi, Jui-Mei Chu, Siao Muk Cheng, Chan-Chuan Liu, Daw-Yang Hwang, Shang-Hung Chen, Kwang-Yu Chang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-14 (2022)
Abstract Background The mechanism by which glioblastoma evades temozolomide (TMZ)-induced cytotoxicity is largely unknown. We hypothesized that mitochondria plays a role in this process. Methods RNA transcriptomes were obtained from tumor samples and
Externí odkaz:
https://doaj.org/article/74d3093ae005449f902018ee36784041
Autor:
An-Chih Wu, Wen-Bin Yang, Kwang-Yu Chang, Jung-Shun Lee, Jing-Ping Liou, Ruei-Yuan Su, Siao Muk Cheng, Daw-Yang Hwang, Ushio Kikkawa, Tsung-I Hsu, Chih-Yang Wang, Wen-Chang Chang, Pin-Yuan Chen, Jian-Ying Chuang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Glioblastoma (GBM) is the most aggressive and lethal brain tumor. Although the histone deacetylase (HDAC)/transcription factor axis promotes growth in GBM, whether HDACs including HDAC6 are involved in modulating long non-coding R
Externí odkaz:
https://doaj.org/article/d9672530025d48d3b6d942240400f4bd
Autor:
Che-Hung Shen, Chi-Che Hsieh, Kuan-Ying Jiang, Chih-Yu Lin, Nai-Jung Chiang, Ting-Wei Li, Chun-Ting Yen, Wan-Ju Chen, Daw-Yang Hwang, Li-Tzong Chen
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-21 (2021)
Abstract Background Ocular adverse events are common dose-limiting toxicities in cancer patients treated with HSP90 inhibitors, such as AUY922; however, the pathology and molecular mechanisms that mediate AUY922-induced retinal toxicity remain undesc
Externí odkaz:
https://doaj.org/article/0c9f94ac3945414a9b0d002161a148a0