Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Davy T. Lee"'
Publikováno v:
Nutrition and Cancer. 61:357-366
To date, the most effective cure for metastatic melanoma remains the surgical resection of the primary tumor. Recently, tocotrienol-rich-fraction has shown antiproliferative effect on cancer cells. To elucidate this anticancer property in malignant m
Publikováno v:
British Journal of Cancer
Tocotrienol-rich fraction (TRF) has demonstrated antiproliferative effect on prostate cancer (PCa) cells. To elucidate this anticancer property in PCa cells, this study aimed, first, to identify the most potent isomer for eliminating PCa cells; and s
Autor:
Xianghong Wang, Davy T. Lee, Yung-Tuen Chiu, Chee Wai Chua, Edward W. Howard, Yong-Chuan Wong
Publikováno v:
International Journal of Cancer. 122:1941-1948
The recent introduction of docetaxel in the treatment of hormone refractory prostate cancer (HRPC) has made a small but significant impact on patient survival. However, its effect is limited by intolerance and resistance. The aim of our study was to
Autor:
Sai Wah Tsao, Xianghong Wang, Hiu Wing Cheung, Xin Yuan Guan, Yong-Chuan Wong, Davy T. Lee, Ming-Tat Ling
Publikováno v:
Oncogene. 23:474-482
Taxol is one of the widely used chemotherapeutic drugs against many types of human cancer. While it is considered as one of the most effective anticancer drugs, treatment failure often occurs due to development of acquired resistance. Therefore, it i
Publikováno v:
Journal of Urology. 167:2598-2602
Purpose: The helix-loop-helix protein Id-1 serves to prevent basic helix-loop-helix transcription factors from binding to DNA, thus, inhibiting the transcription of differentiation associated genes. Over expression of Id-1 has been reported in certai
Autor:
Xianghong Wang, Kwok Wah Chan, Edward W. Howard, Yong-Chuan Wong, Hiu-Fung Yuen, Steve C.L. Leung, Davy T. Lee, Chee Wai Chua
Publikováno v:
Clinicalexperimental metastasis. 25(5)
The presence of circulating tumor cells (CTC) is common in prostate cancer patients, however until recently their clinical significance was unknown. The CTC stage is essential for the formation of distant metastases, and their continuing presence aft
Publikováno v:
BJU international. 99(4)
To evaluate the effect of S-allylcysteine (SAC) on CWR22R, a human androgen-independent (AI) prostate cancer xenograft, in nude mice. Despite extensive research worldwide there is no effective way to control the growth of prostate cancer, and we prev
Publikováno v:
Carcinogenesis. 25(4)
The failure of prostate cancer treatment is largely due to the development of androgen independence, since the androgen depletion therapy remains the front-line option for this cancer. Previously, we reported that over-expression of the helix-loop-he
Autor:
Tian-Yong Fan, Kexin Xu, Davy T. Lee, James J. W. Xuan, Ming-Tat Ling, Xianghong Wang, Yong-Chuan Wong, Sai Wah Tsao, Franky L. Chan
Publikováno v:
Electrophoresis. 24(7-8)
Using two-dimensional gel electrophoresis, we investigated the profile of prostatic secretory proteins in human expressed prostatic secretion (EPS) from benign prostate hyperplasia (BPH) patients and compared the patterns with normal controls. We ide
Publikováno v:
Carcinogenesis. 22(6)
Prostate cancer is the most frequently diagnosed malignancy in the Western world and changes in the ratio of testosterone and estrogens with advancing age is one of the potential risk factors in the development of this disease. However, the molecular