Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Davorka Završnik"'
Autor:
Selma Zukić, Amar Osmanović, Anja Harej Hrkać, Sandra Kraljević Pavelić, Selma Špirtović-Halilović, Elma Veljović, Sunčica Roca, Snežana Trifunović, Davorka Završnik, Uko Maran
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9390 (2024)
The pyrimidine heterocycle plays an important role in anticancer research. In particular, the pyrimidine derivative families of uracil show promise as structural scaffolds relevant to cervical cancer. This group of chemicals lacks data-driven machine
Externí odkaz:
https://doaj.org/article/e84c42e91f2e4a36a4b553b1b5547e41
Autor:
Elma Veljović, Anja Harej, Marko Klobučar, Sandra Kraljević Pavelić, Selma Špirtović-Halilović, Amar Osmanović, Samija Muratović, Mirsada Salihović, Davorka Završnik
Publikováno v:
Kemija u Industriji, Vol 71, Iss 3-4, Pp 131-140 (2022)
Ten biologically active derivatives of 2,6,7-trihydroxyxanthen-3-one, previously synthesized and characterised, were investigated for their in vitro antimicrobial and antiproliferative activity. Compounds were tested on three bacteria, Staphylococcus
Externí odkaz:
https://doaj.org/article/e0091d1815824cada6cd76ef9575b207
Autor:
Una Glamočlija, Selma Špirtović-Halilović, Mirsada Salihović, Iztok Turel, Jakob Kljun, Elma Veljović, Selma Zukić, Davorka Završnik
Publikováno v:
Acta Chimica Slovenica, Vol 68, Iss 1, Pp 144-150 (2021)
Using X-ray single crystal diffraction, the crystal structures of biologically active benzoxazole derivatives were determined. DFT calculation was performed with standard 6-31G*(d), 6-31G** and 6-31+G* basis set to analyze the molecular geometry and
Externí odkaz:
https://doaj.org/article/1efa33284c0a43e58d0e064af07cbb09
Autor:
Elma Veljović, Selma Špirtović-Halilović, Samija Muratović, Sunčica Roca, Snežana Trifunović, Amar Osmanović, Davorka Završnik, Lidija Valek Žulj
Publikováno v:
Croatica Chemica Acta, Vol 88, Iss 2, Pp 121-127 (2015)
Oxidative stress is directly related to several diseases and symptoms, where antioxidant compounds, such as xanthenes, may become important in prevention and/or treatmant. Ten biologically active 9-aryl substituted 2,6,7-trihydroxyxanthen-3-one deriv
Externí odkaz:
https://doaj.org/article/b05d3d1036264090887c923bf9950b14
Autor:
Una Glamočlija, Subhash Padhye, Selma Špirtović-Halilović, Amar Osmanović, Elma Veljović, Sunčica Roca, Irena Novaković, Boris Mandić, Iztok Turel, Jakob Kljun, Snežana Trifunović, Emira Kahrović, Sandra Kraljević Pavelić, Anja Harej, Marko Klobučar, Davorka Završnik
Publikováno v:
Molecules, Vol 23, Iss 12, p 3297 (2018)
Thymoquinone (TQ), a natural compound with antimicrobial and antitumor activity, was used as the starting molecule for the preparation of 3-aminothymoquinone (ATQ) from which ten novel benzoxazole derivatives were prepared and characterized by elemen
Externí odkaz:
https://doaj.org/article/9b94863fddde495dad762a28cdf392be
Autor:
Silvana Raić-Malić, Simon M. Ametamey, Leonardo Scapozza, Davorka Završnik, Ursina Müller, Amar Osmanović, Ivana Novaković, Svjetlana Krištafor, Andrijana Meščić
Publikováno v:
Molecules, Vol 18, Iss 5, Pp 5104-5124 (2013)
The efficient syntheses of 5-(2-hydroxyethyl)- and 5-(3-hydroxypropyl)-substituted pyrimidine derivatives bearing 2,3-dihydroxypropyl, acyclovir-, ganciclovir- and penciclovir-like side chains are reported. A synthetic approach that included the alky
Externí odkaz:
https://doaj.org/article/7e6d1abd87ac407bb52c113da0322b20
Autor:
Janez Plavec, Mario Cetina, Jan Balzarini, Mladen Mintas, Erik De Clercq, Ante Nagl, Samija Muratović, Damjan Makuc, Davorka Završnik
Publikováno v:
Molecules, Vol 16, Iss 7, Pp 6023-6040 (2011)
We report on the synthesis of 4-hydroxycoumarin dimers 1–15 bearing an aryl substituent on the central linker and fused benzopyranocoumarin derivatives 16–20 and on their in vitro broad anti-DNA and RNA virus activity evaluations. The chemical id
Externí odkaz:
https://doaj.org/article/c52443935524412cb71b1ac3efad7682
Publikováno v:
Journal of the Serbian Chemical Society, Vol 75, Iss 2, Pp 243-248 (2010)
Coumarin-based compounds containing a chalcone moiety exhibit antimicrobial activity. These substances are potential drugs and it is important to determine their pKa values. However, they are almost insoluble in water. The dissociation constant was e
Externí odkaz:
https://doaj.org/article/8a8ed17c80c440e581ebaa349fa67831
Publikováno v:
Biomolecules & Biomedicine, Vol 8, Iss 3 (2008)
Due to exceptional reactivity of 4-hydroxycoumarin, the synthesis of new coumarin derivatives of dimer and tetramer type has been carried out. The synthesis was carried out from 4-hydroxycoumarin and various aromatic aldehydes. In this way, compounds
Externí odkaz:
https://doaj.org/article/6f222fa679204472ad500506f5ce4633
Publikováno v:
Biomolecules & Biomedicine, Vol 3, Iss 4 (2003)
In the QSAR (quantitative structure-activity relationship) and QSPR (quantitative structure-property-activity relationship) study physico-chemical property, lipophilicity is used, to predict bioactivity of the newly synthesized coumarin compounds. Li
Externí odkaz:
https://doaj.org/article/c559e366ca75419b97aeccf43095b862