1198 Cytokine affinity tuning and antibody discovery/optimization using the AlphaSeq and AlphaBind platforms to generate targeted immuno-oncology therapeutics

Autor: Ryan Swanson, John Marken, Davis Goodnight, Kimberly Wellman, Jeff Adamo, Emily Engelhart, Oliver Serang, Aditya Agarwal, Cameron Cordray, Samer Halabiya, Kyle Minch, Randolph Lopez

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Externí odkaz: https://doaj.org/article/21fbc0f2587d4b6a9e8c8ca185f63c57

Tuberin levels during cellular differentiation in brain development.

Autor: Fidalgo da Silva E; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Abu Khatir B; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Drouillard C; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Hinch I; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Davis GO; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Sameem M; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Patel R; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Fong J; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Lubanska D; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada., Porter LA; Department of Biomedical Sciences, University of Windsor, 401 Sunset Ave. Windsor, Ontario, N9B 3P4, Canada. Electronic address: lporter@uwindsor.ca.

Publikováno v: Differentiation; research in biological diversity [Differentiation] 2023 Mar-Apr; Vol. 130, pp. 43-50. Date of Electronic Publication: 2022 Dec 24.

High-throughput allele-specific expression across 250 environmental conditions.

Autor: Moyerbrailean GA; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA., Richards AL; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA., Kurtz D; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA., Kalita CA; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA., Davis GO; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA., Harvey CT; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA., Alazizi A; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA., Watza D; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA., Sorokin Y; Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan 48201, USA., Hauff N; Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan 48201, USA., Zhou X; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA., Wen X; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA., Pique-Regi R; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA.; Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan 48201, USA., Luca F; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan 48201, USA.; Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan 48201, USA.

Publikováno v: Genome research [Genome Res] 2016 Dec; Vol. 26 (12), pp. 1627-1638. Date of Electronic Publication: 2016 Oct 19.

QuASAR: quantitative allele-specific analysis of reads.

Autor: Harvey CT; Center for Molecular Medicine and Genetics, Department of Obstetrics and Gynecology, Wayne State University, 540 E Canfield, Scott Hall, Detroit, MI 48201, USA and Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Moyerbrailean GA; Center for Molecular Medicine and Genetics, Department of Obstetrics and Gynecology, Wayne State University, 540 E Canfield, Scott Hall, Detroit, MI 48201, USA and Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Davis GO; Center for Molecular Medicine and Genetics, Department of Obstetrics and Gynecology, Wayne State University, 540 E Canfield, Scott Hall, Detroit, MI 48201, USA and Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Wen X; Center for Molecular Medicine and Genetics, Department of Obstetrics and Gynecology, Wayne State University, 540 E Canfield, Scott Hall, Detroit, MI 48201, USA and Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Luca F; Center for Molecular Medicine and Genetics, Department of Obstetrics and Gynecology, Wayne State University, 540 E Canfield, Scott Hall, Detroit, MI 48201, USA and Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA., Pique-Regi R; Center for Molecular Medicine and Genetics, Department of Obstetrics and Gynecology, Wayne State University, 540 E Canfield, Scott Hall, Detroit, MI 48201, USA and Department of Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

Publikováno v: Bioinformatics (Oxford, England) [Bioinformatics] 2015 Apr 15; Vol. 31 (8), pp. 1235-42. Date of Electronic Publication: 2014 Dec 04.