Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Davina Gorton"'
Autor:
Catherine M. Rush, Davina Gorton, Natkunam Ketheesan, Suchandan Sikder, Natasha L. Williams, Brenda Govan, Madeleine W. Cunningham, Lisa Chilton
Publikováno v:
Autoimmunity. 49:563-570
Rheumatic fever and rheumatic heart disease (RF/RHD) develop following repeated infection with group A streptococci (GAS). We used the Rat Autoimmune Valvulitis (RAV) model of RF/RHD to demonstrate that repetitive booster immunization with GAS-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8b2e1cec674c85c23d16c067d32635
https://doi.org/10.1080/08916934.2016.1217999
https://doi.org/10.1080/08916934.2016.1217999
Autor:
James S. McCarthy, Ainslie Calcutt, Michael R. Batzloff, Catherine M. Rush, Jon Hartas, Natkunam Ketheesan, Manisha Pandey, Davina Gorton, Linda K. Johnson, Grace Yeung, Tania Rivera-Hernandez, Michael F. Good, Anne Fane
Publikováno v:
Human Vaccines & Immunotherapeutics. 12:3089-3096
Streptococcus pyogenes (group A streptococcus, GAS) causes a wide range of clinical manifestations ranging from mild self-limiting pyoderma to invasive diseases such as sepsis. Also of concern are the post-infectious immune-mediated diseases includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3db3de4ee9f933833ba8d0d36d54c62
https://doi.org/10.1080/21645515.2016.1222999
https://doi.org/10.1080/21645515.2016.1222999
Publikováno v:
International Congress Series. 1289:289-292
Rheumatic heart disease (RHD) is an autoimmune disease mediated by group A streptococcal (GAS) infection. To study the immune mechanisms underlying RHD, a robust animal model with immunopathology similar to that seen in humans is essential. A Lewis r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ec2574d381a50d67645e8909a324f4f
https://doi.org/10.1016/j.ics.2005.11.079
https://doi.org/10.1016/j.ics.2005.11.079
Publikováno v:
International Congress Series. 1289:81-84
Streptococcal toxic shock syndrome (STSS) is an uncommon but important complication of invasive group A streptococcal (GAS) disease. A number of clinical risk factors and molecular markers have been linked with STSS. We report here a case controlled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::332a29489df5f25a428972bf4a2e1fa1
https://doi.org/10.1016/j.ics.2005.09.085
https://doi.org/10.1016/j.ics.2005.09.085
Publikováno v:
Journal of immunological methods. 355(1-2)
We currently use a rat model in our investigations into human rheumatic heart disease (RHD). This model traditionally involves footpad immunization with antigen emulsified in complete Freund's adjuvant (CFA). Trials to find an alternative adjuvant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a935d8f83b4112a2e16018f227d0f2
https://pubmed.ncbi.nlm.nih.gov/20206182
https://pubmed.ncbi.nlm.nih.gov/20206182
B- and T-cell responses in group a streptococcus M-protein- or Peptide-induced experimental carditis
Publikováno v:
Infection and immunity. 77(5)
The etiology of rheumatic fever and rheumatic heart disease (RF/RHD) is believed to be autoimmune, involving immune responses initiated between streptococcal and host tissue proteins through a molecular mimicry mechanism(s). We sought to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2773e723bfb7d77a33eff5ff6ab3b1
https://pubmed.ncbi.nlm.nih.gov/19273562
https://pubmed.ncbi.nlm.nih.gov/19273562
Publikováno v:
Microbes and infection. 7(3)
The fibronectin-binding proteins (FnBPs) PrtF1 and PrtF2 are considered to be major group A streptococcal virulence factors, mediating adherence to and internalisation of host cells. The present study investigated an association between the presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba33b44bc644207ec3182acb3da6a79
https://pubmed.ncbi.nlm.nih.gov/15792638
https://pubmed.ncbi.nlm.nih.gov/15792638