Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Davie, Cappoen"'
Autor:
Clara M. Bento, Kevin van Calster, Tatiana Piller, Gabriel S. Oliveira, Linda de Vooght, Davie Cappoen, Paul Cos, M. Salomé Gomes, Tânia Silva
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Mycobacterium abscessus (Mab) is an emerging pathogen that poses a severe health threat, especially in people with cystic fibrosis and other chronic lung diseases. Available drugs are largely ineffective due to an exquisite intrinsic resista
Externí odkaz:
https://doaj.org/article/560d5dfe8a07432fafc1a54d9968bc84
Autor:
Natalia Smiejkowska, Lauren Oorts, Kevin Van Calster, Linda De Vooght, Rob Geens, Henri-Philippe Mattelaer, Koen Augustyns, Sergei V. Strelkov, Dirk Lamprecht, Koen Temmerman, Yann G.-J. Sterckx, Davie Cappoen, Paul Cos
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTThe World Health Organization’s goal to combat tuberculosis (TB) is hindered by the emergence of anti-microbial resistance, therefore necessitating the exploration of new drug targets. Multidrug regimens are indispensable in TB therapy as t
Externí odkaz:
https://doaj.org/article/c8fac40f6384460fafe887ecb260e268
Autor:
Yanlin Jian, Martijn D. P. Risseeuw, Mathy Froeyen, Lijun Song, Davie Cappoen, Paul Cos, Hélène Munier-Lehmann, Serge van Calenbergh
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1730-1739 (2019)
A series of readily accessible 1-(piperidin-3-yl)thymine amides was designed, synthesised and evaluated as Mycobacterium tuberculosis TMPK (MtbTMPK) inhibitors. In line with the modelling results, most inhibitors showed reasonable MtbTMPK inhibitory
Externí odkaz:
https://doaj.org/article/60a10e54b7c64ecbbe4411d5e94387b7
Autor:
Silvia del Carmen Molina Bertrán, Lianet Monzote, Davie Cappoen, Julio Cesar Escalona Arranz, Mario Juan Gordillo Pérez, Annarli O. Rodríguez-Ferreiro, Idelsy Chill Nuñez, Claudina Pérez Novo, Daniel Méndez, Paul Cos, Gabriel Llauradó Maury
Publikováno v:
Molecules, Vol 27, Iss 15, p 5009 (2022)
The increase in antibiotic resistance demands innovative strategies to combat microorganisms. The current study evaluated the antibacterial and antivirulence effects of ethanol extracts from Persea americana seeds obtained by the Soxhlet (SE) and mac
Externí odkaz:
https://doaj.org/article/9694aa2426c1465a82eff2f7f147d148
Autor:
Freya Cools, Eveline Torfs, Juliana Aizawa, Bieke Vanhoutte, Louis Maes, Guy Caljon, Peter Delputte, Davie Cappoen, Paul Cos
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Streptococcus pneumoniae is the leading cause of bacterial pneumonia. Infection is linked to high morbidity and mortality rates and antibiotic resistance within this pathogen is on the rise. Therefore, there is a need for novel antimicrobial therapie
Externí odkaz:
https://doaj.org/article/63acaaf0e7fa4ec7851538ecc1bdc5c2
Autor:
Gabriel Llauradó Maury, Humberto J. Morris-Quevedo, Annick Heykers, Ellen Lanckacker, Davie Cappoen, Peter Delputte, Wim Vanden Berghe, Zelene Salgueiro, Paul Cos
Publikováno v:
Journal of Fungi, Vol 7, Iss 3, p 206 (2021)
Pleurotus ostreatus mushroom preparations have been investigated because of their ability to modulate the immune function. However, there is still no consensus regarding the activation and polarizing effect on macrophages by Pleurotus-derived bioprod
Externí odkaz:
https://doaj.org/article/e3ed9ff613ae4b36b0b8e23e2987dcd7
Autor:
Boddupalli Venkata Siva Kumar, Yogesh Mahadu Khetmalis, Adinarayana Nandikolla, Banoth Karan Kumar, Kevin Van Calster, Sankaranarayanan Murugesan, Davie Cappoen, Kondapalli Venkata Gowri Chandra Sekhar
Publikováno v:
Chemistry & biodiversity
A series of novel 2-substituted-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carbohydrazide were designed, synthesized and structures were confirmed by analytical methods, viz., H-1-NMR, C-13-NMR and Mass spectrometry. Synthesized derivatives were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7924696c46f8e3f6cc0e923932f73b69
https://hdl.handle.net/10067/1943010151162165141
https://hdl.handle.net/10067/1943010151162165141
Autor:
Freija Van den Driessche, Bieke Vanhoutte, Gilles Brackman, Aurélie Crabbé, Petra Rigole, Jurgen Vercruysse, Glenn Verstraete, Davie Cappoen, Chris Vervaet, Paul Cos, Tom Coenye
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172723 (2017)
Burkholderia cenocepacia is an opportunistic pathogen responsible for life-threatening infections in cystic fibrosis patients. B. cenocepacia is extremely resistant towards antibiotics and therapy is complicated by its ability to form biofilms. We in
Externí odkaz:
https://doaj.org/article/37b26a9a5bf940ea8bf5ab8b2e8ccdba
Autor:
Surendar, Chitti, Kevin, Van Calster, Davie, Cappoen, Adinarayana, Nandikolla, Yogesh Mahadu, Khetmalis, Paul, Cos, Banoth Karan, Kumar, Sankaranarayanan, Murugesan, Kondapalli Venkata, Gowri Chandra Sekhar
Publikováno v:
RSC advances. 12(35)
In the search for new anti-mycobacterial agents, we revealed the importance of imidazo-[2,1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42e9210154e9cfc1fc29e812be849269
https://pubmed.ncbi.nlm.nih.gov/36105967
https://pubmed.ncbi.nlm.nih.gov/36105967
Autor:
Surendar Chitti, Adinarayana Nandikolla, Yogesh Mahadu Khetmalis, Kevin Van Calster, Boddupalli Venkata Siva Kumar, Banoth Karan Kumar, Sankaranarayanan Murugesan, Davie Cappoen, Kondapalli Venkata Gowri Chandra Sekhar
Publikováno v:
Chemistry & biodiversity
A series of novel spiro-[chromane-2,4'-piperidin]-4(3H)-one derivatives were designed, synthesized and structures were confirmed by analytical methods, viz., H-1-NMR, C-13-NMR and mass spectrometry. The synthetic derivatives were evaluated for their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fd73ad85cb61e5e5017bb041897503
https://pubmed.ncbi.nlm.nih.gov/35821618
https://pubmed.ncbi.nlm.nih.gov/35821618