SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation

Autor: Palomer FX, Román-Azcona MS, Pizarro J, Planavila A, Villarroya F, Valenzuela-Alcaraz BI, Crispi F, Sepúlveda-Martínez Á, Miguel-Escalada I, Ferrer J, Nistal JF, García R, Davidson MM, Barroso E, Vazquez M

Publikováno v: signal transduction and targeted therapy
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Sirtuin 3 (SIRT3) is a deacetylase that modulates proteins that control metabolism and protects against oxidative stress. Modulation of SIRT3 activity has been proposed as a promising therapeutic target for ameliorating metabolic diseases and associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::12239517c1376719679e8edbb4e32c7c
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17474

Apis mellifera and Megachile rotundata: a comparison of behaviour and seed yield in a hybrid carrot seed crop.

Autor: Davidson, MM¹ (AUTHOR) davidsonm@crop.cri.nz, Butler, RC¹ (AUTHOR), Howlett, BG¹ (AUTHOR)

Publikováno v: New Zealand Journal of Crop & Horticultural Science. Jun2010, Vol. 38 Issue 2, p113-117. 5p. 1 Chart, 1 Graph.

PPAR beta/delta attenuates palmitate-induced endoplasmic reticulum stress and induces autophagic markers in human cardiac cells

Autor: Palomer FX, Capdevila-Busquets E, Botteri G, Salvadó L, Barroso E, Davidson MM, Michalik L, Wahli W, Vazquez M

Publikováno v: INTERNATIONAL JOURNAL OF CARDIOLOGY
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Chronic endoplasmic reticulum (ER) stress contributes to the apoptotic cell death in the myocardium, thereby playing a critical role in the development of cardiomyopathy. ER stress has been reported to be induced after high-fat diet feeding in mice a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::29878a92e9199e243104be332b6b333a
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=12018

The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells

Autor: Palomer FX, Álvarez-Guardia D, Davidson MM, Chan TO, Feldman AM, Vazquez M

Publikováno v: PLoS One
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r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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Pyruvate dehydrogenase kinase 4 (PDK4) inhibition by nuclear factor-?B (NF-?B) is related to a shift towards increased glycolysis during cardiac pathological processes such as cardiac hypertrophy and heart failure. The transcription factors estrogen-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5c2f5cb2ace89d20ce4793fd0b1643ee
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=12038

TNF-alpha reduces PGC-1alpha expression through NF-kappaB and p38 MAPK leading to increased glucose oxidation in a human cardiac cell model

Autor: Palomer FX, Alvarez-Guardia D, Rodríguez-Calvo R, Coll T, Laguna JC, Davidson MM, Chan TO, Feldman AM, Vazquez M

Publikováno v: CARDIOVASC RES
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Inflammatory responses in the heart that are driven by sustained increases in cytokines have been associated with several pathological processes, including cardiac hypertrophy and heart failure. Emerging data suggest a link between cardiomyopathy and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::248fcc130092679bb1561ffad11e45b4
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=11986