Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Davide Sala"'
Autor:
Emiliano Pioltelli, Lorenzo Guzzetti, Paolo Biella, Davide Sala, Andrea Copetta, Paolo Mussano, Andrea Galimberti, Massimo Labra
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract In this study, we experimentally addressed the impact of different pollination treatments on the morphological, reproductive and chemical traits of fruits and seeds of two crop species, the wild strawberry (Fragaria vesca L.) and cowpea (Vig
Externí odkaz:
https://doaj.org/article/a1dc2d3ba889403196334d163452f679
Autor:
Davide Sala, Francesca Ornaghi, Francesco Morena, Chiara Argentati, Manuela Valsecchi, Valeria Alberizzi, Roberta Di Guardo, Alessandra Bolino, Massimo Aureli, Sabata Martino, Angela Gritti
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 170-189 (2022)
Genetic deficiency of β-N-acetylhexosaminidase (Hex) functionality leads to accumulation of GM2 ganglioside in Tay-Sachs disease and Sandhoff disease (SD), which presently lack approved therapies. Current experimental gene therapy (GT) approaches wi
Externí odkaz:
https://doaj.org/article/61bdd9f6fc0d43f78a06d041a2b5f2f0
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Determining the three-dimensional structure of proteins in their native functional states has been a longstanding challenge in structural biology. While integrative structural biology has been the most effective way to get a high-accuracy structure o
Externí odkaz:
https://doaj.org/article/7ad60cbd2fa9450285cc17b01fb01e18
Autor:
Giulia Rubiu, Marco Bologna, Michaela Cellina, Maurizio Cè, Davide Sala, Roberto Pagani, Elisa Mattavelli, Deborah Fazzini, Simona Ibba, Sergio Papa, Marco Alì
Publikováno v:
Applied Sciences, Vol 13, Iss 13, p 7947 (2023)
Background and purpose: Accurate instance segmentation of teeth in panoramic dental X-rays is a challenging task due to variations in tooth morphology and overlapping regions. In this study, we propose a new algorithm, for instance, segmentation of t
Externí odkaz:
https://doaj.org/article/4540761d951143cca48b9f0345444f15
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
AimThe aim of this study was to explore the potential intraprocedural benefits of the Proximal Side Optimization (PSO) technique by Optical Coherence Tomography (OCT).MethodsA case series of 10 consecutive true bifurcation lesions, with severe long p
Externí odkaz:
https://doaj.org/article/8639a8e491f441e09c9de1b66c6bf817
Publikováno v:
eLife, Vol 11 (2022)
Equilibrium fluctuations and triggered conformational changes often underlie the functional cycles of membrane proteins. For example, transporters mediate the passage of molecules across cell membranes by alternating between inward- and outward-facin
Externí odkaz:
https://doaj.org/article/cc2a5f25a21b4d9fac2ad36ac9cb3bba
Autor:
Davide Sala, Linda Cerofolini, Marco Fragai, Andrea Giachetti, Claudio Luchinat, Antonio Rosato
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 114-124 (2020)
Protein assemblies are involved in many important biological processes. Solid-state NMR (SSNMR) spectroscopy is a technique suitable for the structural characterization of samples with high molecular weight and thus can be applied to such assemblies.
Externí odkaz:
https://doaj.org/article/bab26ed89607479c91b5bdf3d1f5aed3
Autor:
Francesca Ornaghi, Davide Sala, Fabiana Tedeschi, Maria Chiara Maffia, Martina Bazzucchi, Francesco Morena, Manuela Valsecchi, Massimo Aureli, Sabata Martino, Angela Gritti
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
The favorable outcome of in vivo and ex vivo gene therapy approaches in several Lysosomal Storage Diseases suggests that these treatment strategies might equally benefit GM2 gangliosidosis. Tay-Sachs and Sandhoff disease (the main forms of GM2 gangli
Externí odkaz:
https://doaj.org/article/e5ebadf6d2734a15bfc0f9c89dc37813
Publikováno v:
AIMS Biophysics, Vol 5, Iss 1, Pp 77-96 (2018)
The constant increase of computational power has made feasible to investigate the folding mechanism of small proteins using molecular dynamics (MD). Metal-binding proteins (metalloproteins) are usually complicated to model, largely due to the presenc
Externí odkaz:
https://doaj.org/article/b139bed48c964424a0956cd444457f6d
Publikováno v:
Life, Vol 10, Iss 7, p 110 (2020)
Intrinsically Disordered Peptides and Proteins (IDPs) in solution can span a broad range of conformations that often are hard to characterize by both experimental and computational methods. However, obtaining a significant representation of the confo
Externí odkaz:
https://doaj.org/article/c6b0b65655b9497f87ac4b109837a639