Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Davide Renier"'
Autor:
Isabella Monia Montagner, Anna Merlo, Gaia Zuccolotto, Davide Renier, Monica Campisi, Gianfranco Pasut, Paola Zanovello, Antonio Rosato
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112240 (2014)
Peritoneal carcinomatosis still lacks reliable therapeutic options. We aimed at testing a drug delivery strategy allowing a controlled release of cytotoxic molecules and selective targeting of tumor cells. We comparatively assessed the efficacy of a
Externí odkaz:
https://doaj.org/article/f7dd7a5368984381b534ae5dc638e70c
Publikováno v:
Macromolecular Chemistry and Physics. 215:140-147
The unique performance of a partially hydrophobic derivative of hyaluronic acid, HYADD4, bearing 2–3 hexadecylic side chains every 100 repeating units, enables hydrogels based on this polymer to be suitably used as a viscosupplement to replace syno
Autor:
Davide Renier, Alessandra Banzato, Antonio Rosato, Paola Zanovello, Pierfrancesco Bassi, Gaia Zuccolotto, Isabella Monia Montagner, Monica Campisi
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 31:1261-1269
Objectives A previously described hydrosoluble paclitaxel-hyaluronan bioconjugate appears particularly well suited for treatment of superficial bladder cancer because of its in vitro cytotoxic profile against urothelial carcinoma (UC) cell lines and
Publikováno v:
Carbohydrate Polymers. 97:321-326
Five amide derivatives of Hyaluronic Acid (HA) were synthesized with C8, C12, C15, C16 and C18 linear alkyl-amines. These polymers (Hyadd) were tested against thermal, oxidative and hyaluronidase degradation by means of rheological experiments and SE
Publikováno v:
Carbohydrate Polymers. 92:2163-2170
Polymer conjugation has been widely exploited to prolong half-life and reduce immunogenicity of therapeutic proteins. Here, the potentials of hyaluronic acid (HA) have been investigated by studying the conjugates with two model enzymes, trypsin and R
Autor:
Arianna Loregian, Antonio Rosato, Gianfranco Pasut, Anna Dalla Pietà, Debora Carpanese, Anna Mero, Isabella Monia Montagner, Monica Campisi, Paola Zanovello, Davide Renier, Antonella Grigoletto, Anna Merlo
While interferon alpha (IFNα) is used in several viral and cancer contexts, its efficacy against ovarian cancer (OC) is far from being incontrovertibly demonstrated and, more importantly, is hindered by heavy systemic side effects. To overcome these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29997369b7424497887a55532c82142
http://hdl.handle.net/11577/3192465
http://hdl.handle.net/11577/3192465
Publikováno v:
Carbohydrate Polymers. 88:428-434
The cross-link efficiency in hyaluronan fillers was determined by means of triple detector (RI, LALS-RALS and a Differential Viscometer) GPC/SEC in aqueous buffer. The low water solubility of HA cross-linked with BDDE (HBC) was overcome with an alkal
Autor:
Monica Campisi, Davide Renier
Publikováno v:
Current Bioactive Compounds. 7:27-32
Publikováno v:
Biorheology. 48:263-275
A novel partially hydrophobized derivative of hyaluronic acid (HYADD® 4), containing a low number of C16 side-chains per polysaccharide backbone, provides injectable hydrogels stabilized by side-chain hydrophobic interactions. The rheological proper
Autor:
Gilda De Luca, Fabio Bettella, Pierfrancesco Bassi, Claudio Pagano, Davide Renier, Giovanni Esposito, Antonio Rosato, Paola Zanovello, Alessandra Banzato
Publikováno v:
Urologic Oncology: Seminars and Original Investigations. 24:207-215
Objective To report the development of a new water-soluble paclitaxel-hyaluronic acid bioconjugate, HYTAD1-p20, for intravesical treatment of superficial bladder cancer. Materials and Methods HYTAD1-p20 was synthesized by carboxyl esterification of h