Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Davide M. Ferraris"'
Autor:
Edoardo L. M. Gelardi, Diego Caprioglio, Giorgia Colombo, Erika Del Grosso, Daniele Mazzoletti, Daiana Mattoteia, Stefano Salamone, Davide M. Ferraris, Eleonora Aronica, Giulia Nato, Annalisa Buffo, Menico Rizzi, Lorenzo Magrassi, Alberto Minassi, Silvia Garavaglia
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Curcumin-based fluorescent probes are presented that are able to selectively bind to aldehyde dehydrogenase 1A3 (ALDH1A3), an enzyme overexpressed in glioma stem cells and specifically identify glioblastoma cells in vitro and in vivo.
Externí odkaz:
https://doaj.org/article/838a6897499445dba59ff3225c0ef774
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3874-3883 (2022)
Computational methods for protein structure prediction have made significant strides forward, as evidenced by the last development of the neural network AlphaFold, which outperformed the CASP14 competitors by consistently predicting the structure of
Externí odkaz:
https://doaj.org/article/302d3f62093c44ab8273b5bf3ff3193f
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The Mycobacterium tuberculosis orotate phosphoribosyltransferase (MtOPRT) catalyses the conversion of α-D-5-phosphoribosyl-1-pyrophosphate (PRPP) and orotate (OA) in pyrophosphate and orotidine 5′-monophosphate (OMP), in presence of Mg2+.
Externí odkaz:
https://doaj.org/article/0ec3c764078249c39a6a0b3f9b936c3b
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Kynurenic acid (KYNA) is a bioactive compound that is produced along the kynurenine pathway (KP) during tryptophan degradation. In a few decades, KYNA shifted from being regarded a poorly characterized by-product of the KP to being considered a main
Externí odkaz:
https://doaj.org/article/db429b5a976b439e8fe653fe03649d70
Publikováno v:
Pathogens, Vol 9, Iss 5, p 385 (2020)
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global T
Externí odkaz:
https://doaj.org/article/fd752cdd8dd64437aaee287afa61b593
Publikováno v:
Pathogens, Vol 7, Iss 1, p 17 (2018)
Mycobacterium tuberculosis is the causative agent of tuberculosis, an ancient disease which, still today, represents a major threat for the world population. Despite the advances in medicine and the development of effective antitubercular drugs, the
Externí odkaz:
https://doaj.org/article/a78abad3bb2e46ad9b62f73652d62865
Autor:
Stefano Sainas, Marta Giorgis, Paola Circosta, Giulio Poli, Marta Alberti, Alice Passoni, Valentina Gaidano, Agnese C. Pippione, Nicoletta Vitale, Davide Bonanni, Barbara Rolando, Alessandro Cignetti, Cristina Ramondetti, Alessia Lanno, Davide M. Ferraris, Barbara Canepa, Barbara Buccinnà, Marco Piccinini, Menico Rizzi, Giuseppe Saglio, Salam Al-Karadaghi, Donatella Boschi, Riccardo Miggiano, Tiziano Tuccinardi, Marco L. Lolli
Publikováno v:
Journal of Medicinal Chemistry. 65:12701-12724
Publikováno v:
Acta Crystallographica Section D Structural Biology. 76:496-505
L-Hydroxyproline (L-Hyp) is a nonstandard amino acid that is present in certain proteins, in some antibiotics and in the cell-wall components of plants. L-Hyp is the product of the post-translational modification of protein prolines by prolyl hydroxy
Publikováno v:
Biochemical and Biophysical Research Communications. 516:189-195
Hydroxyprolines (Hyp) are non-standard amino acids derived from the post-translational modification of proteins by prolyl hydroxylase enzymes. Some plants and bacteria produce Hyp, and the isomers trans-3-Hydroxy-l-proline (T3LHyp) and trans-4-Hydrox
Autor:
Shibin Chacko, Helena I. M. Boshoff, Vinayak Singh, Davide M. Ferraris, Deviprasad R. Gollapalli, Minjia Zhang, Ann P. Lawson, Michael J. Pepi, Andrzej Joachimiak, Menico Rizzi, Valerie Mizrahi, Gregory D. Cuny, Lizbeth Hedstrom
Publikováno v:
Journal of Medicinal Chemistry. 64:18233-18234