Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Davide Foletti"'
Autor:
Shan-Shan Zhang, Lance Larrabee, Andrew H. Chang, Sapna Desai, Lisa Sloan, Xin Wang, Yixuan Wu, Nazia Parvez, Karen Amaratunga, Allison C. Hartman, Abby Whitnall, Joseph Mason, Nicholas P. Barton, Audrey Y. Chu, Jonathan M. Davitte, Adam J. Csakai, Caitlin Vestal Tibbetts, Audrey E. Tolbert, Heather O’Keefe, Jessie Polanco, Joseph Foley, Casey Kmett, Jonathan Kehler, Gabriela Kozejova, Feng Wang, Andrew P. Mayer, Patrick Koenig, Davide Foletti, Steven J. Pitts, Christine G. Schnackenberg
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Hypertension remains a leading cause of cardiovascular and kidney diseases. Failure to control blood pressure with ≥ 3 medications or control requiring ≥ 4 medications is classified as resistant hypertension (rHTN) and new therapies are
Externí odkaz:
https://doaj.org/article/c1b96aec0fcd4bf58710e7f61b920681
Autor:
Yik Andy Yeung, Davide Foletti, Xiaodi Deng, Yasmina Abdiche, Pavel Strop, Jacob Glanville, Steven Pitts, Kevin Lindquist, Purnima D. Sundar, Marina Sirota, Adela Hasa-Moreno, Amber Pham, Jody Melton Witt, Irene Ni, Jaume Pons, David Shelton, Arvind Rajpal, Javier Chaparro-Riggers
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Staphylococcus aureuscan both cause disease in humans and be present with no discernible effect. Here, the authors look in detail at the memory immune response against a protein involved in iron acquisition.
Externí odkaz:
https://doaj.org/article/2761e2c97b344bc6b55beb67dcda4616
Autor:
Magdalena Dorywalska, Pavel Strop, Jody A Melton-Witt, Adela Hasa-Moreno, Santiago E Farias, Meritxell Galindo Casas, Kathy Delaria, Victor Lui, Kris Poulsen, Janette Sutton, Gary Bolton, Dahui Zhou, Ludivine Moine, Russell Dushin, Thomas-Toan Tran, Shu-Hui Liu, Mathias Rickert, Davide Foletti, David L Shelton, Jaume Pons, Arvind Rajpal
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132282 (2015)
The efficacy of an antibody-drug conjugate (ADC) is dependent on the properties of its linker-payload which must remain stable while in systemic circulation but undergo efficient processing upon internalization into target cells. Here, we examine the
Externí odkaz:
https://doaj.org/article/523b58d2569a488d9bf12b8cb87145b2
Autor:
Yasmina Noubia Abdiche, Adam Miles, Josh Eckman, Davide Foletti, Thomas J Van Blarcom, Yik Andy Yeung, Jaume Pons, Arvind Rajpal
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92451 (2014)
Here, we demonstrate how array-based label-free biosensors can be applied to the multiplexed interaction analysis of large panels of analyte/ligand pairs, such as the epitope binning of monoclonal antibodies (mAbs). In this application, the larger th
Externí odkaz:
https://doaj.org/article/e1995642182a41caada3267f6a733df6
Autor:
Pavel Strop, Arvind Rajpal, David L. Shelton, Jaume Pons, Christopher J. O'Donnell, Davide Foletti, Shu-Hui Liu, Kathy Delaria, Thomas-Toan Tran, Meritxell Galindo Casas, Adela Hasa-Moreno, Victor Lui, Thayalan Navaratnam, Dahui Zhou, Santiago E. Farias, Ludivine Moine, Russell Dushin, Magdalena Dorywalska
Experimental Procedures for the Preparation of Linker-Payloads.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a221c603c7097472189eaf46ce305d
https://doi.org/10.1158/1535-7163.22508245.v1
https://doi.org/10.1158/1535-7163.22508245.v1
Autor:
Pavel Strop, Arvind Rajpal, David L. Shelton, Jaume Pons, Christopher J. O'Donnell, Davide Foletti, Shu-Hui Liu, Kathy Delaria, Thomas-Toan Tran, Meritxell Galindo Casas, Adela Hasa-Moreno, Victor Lui, Thayalan Navaratnam, Dahui Zhou, Santiago E. Farias, Ludivine Moine, Russell Dushin, Magdalena Dorywalska
S1. Enrichment of VC-PABC hydrolysis activity by mouse serum fractionation. S2. Testing of mouse serum enzymes for the VC-PABC linker hydrolysis activity. S3. Testing of mouse serum enzymes for cleavage activity towards the non-cleavable amino-PEG6-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07f5767e7793d3073dc403b33870b7e
https://doi.org/10.1158/1535-7163.22508248
https://doi.org/10.1158/1535-7163.22508248
Autor:
Pavel Strop, Russell Dushin, Janette Sutton, Guoyun Zhu, Davide Foletti, David L. Shelton, Shu-Hui Liu, Charles Holz, Arvind Rajpal, Hong Liang, Jaume Pons, Rachel M. DeVay, Gary Louis Bolton, Christine Bee, Kathy Delaria
Publikováno v:
Bioconjugate Chemistry. 28:1102-1114
Antibody drug conjugates (ADCs) provide an efficacious and relatively safe means by which chemotherapeutic agents can be specifically targeted to cancer cells. In addition to the selection of antibody targets, ADCs offer a modular design that allows
Autor:
Davide Foletti, Tina Mistry, Javier Chaparro-Riggers, Guoyun Zhu, Amy H. Yang, Xiaohui Liu, Pavel Strop, Charles Holz, Shu-Hui Liu, Laura Aschenbrenner, Thomas Van Blarcom, Winston Evering, Chenyu Lee, Adela Hasa-Moreno, Tao Sai, Eugenia Kraynov, Mathias Rickert, Sheng Ding, Kevin Lindquist, Jody Melton Witt, Leslie A. Obert
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Human CLDN18.2 is highly expressed in a significant proportion of gastric and pancreatic adenocarcinomas, while normal tissue expression is limited to the epithelium of the stomach. The restricted expression makes it a potential drug target for the t
Autor:
Sheng Ding, Tina Mistry, Tao Sai, Javier Chaparro-Riggers, Winston Evering, Guoyun Zhu, Pavel Strop, Jody Melton Witt, Amy H. Yang, Xiaohui Liu, Kevin Lindquist, Leslie A. Obert, Davide Foletti, Laura Aschenbrenner, Charles Holz, Adela Hasa-Moreno, Eugenia Kraynov, Mathias Rickert, Shu-Hui Liu, Chenyu Lee, Thomas Van Blarcom
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
Thomas, Van Blarcom, Andrea, Rossi, Davide, Foletti, Purnima, Sundar, Steven, Pitts, Zea, Melton, Dilduz, Telman, Lora, Zhao, Wai Ling, Cheung, Jan, Berka, Wenwu, Zhai, Pavel, Strop, Jaume, Pons, Arvind, Rajpal, Javier, Chaparro-Riggers
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1785
Monoclonal antibodies are the largest class of therapeutic proteins due in part to their ability to bind an antigen with a high degree of affinity and specificity. A precise determination of their epitope is important for gaining insights into their