Reactive oxygen species spermine metabolites generated from amine oxidases and radiation represent a therapeutic gain in cancer treatments

Autor: Davide E. Sallustio, Taichi Ueshima, Enzo Agostinelli, Manuela Cervelli, G. Tempera, Roberto Amendola, Emiliano Fratini, Paolo Mariottini

Publikováno v: International Journal of Oncology
International Journal of Oncology, Spandidos Publications, 2013, 43 (3), pp.813-20. <10.3892/ijo.2013.2013>
International Journal of Oncology, Spandidos Publications, 2013, 43 (3), pp.813-20. ⟨10.3892/ijo.2013.2013⟩

International audience; The most frequent interventions in cancer therapy are currently the destruction of cells by irradiation or administration of drugs both able to induce radical formation and toxic metabolites by enzyme-catalyzed reactions. The

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