Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Davide Chiarugi"'
Autor:
Samuel Furse, Denise S. Fernandez-Twinn, Jessica H. Beeson, Davide Chiarugi, Susan E. Ozanne, Albert Koulman
Publikováno v:
Nutrition & Diabetes, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Background Gestational diabetes is associated with increased risk of type 2 diabetes mellitus and cardiovascular disease for the mother in the decade after delivery. However, the molecular mechanisms that drive these effects are unknown. Rec
Externí odkaz:
https://doaj.org/article/e4d6352846024f0098ef7a1ae2c28d9f
Autor:
Samuel Furse, Samuel Virtue, Stuart G. Snowden, Antonio Vidal-Puig, Philip C. Stevenson, Davide Chiarugi, Albert Koulman
Publikováno v:
Molecular Metabolism, Vol 59, Iss , Pp 101457- (2022)
Objective: Polyunsaturated fatty acid (PUFA) supplements have been trialled as a treatment for a number of conditions and produced a variety of results. This variety is ascribed to the supplements, that often comprise a mixture of fatty acids, and to
Externí odkaz:
https://doaj.org/article/07370932cfd04abbb2b26d8fc678dc0e
Autor:
Samuel Furse, Adam J. Watkins, Nima Hojat, James Smith, Huw E. L. Williams, Davide Chiarugi, Albert Koulman
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Furse et al. use a purpose-built computational tool called Lipid Traffic Analysis to determine the spatial distribution of lipids throughout an organism. They use it to show that high paternal carbohydrate intake influences lipid metabolism in offspr
Externí odkaz:
https://doaj.org/article/69145bc415ce485fab5b9db61c31538e
Autor:
Giorgia Giacomini, Caterina Graziani, Veronica Lachi, Pietro Bongini, Niccolò Pancino, Monica Bianchini, Davide Chiarugi, Angelo Valleriani, Paolo Andreini
Publikováno v:
Algorithms, Vol 15, Iss 8, p 274 (2022)
In recent years, the Ribosome profiling technique (Ribo–seq) has emerged as a powerful method for globally monitoring the translation process in vivo at single nucleotide resolution. Based on deep sequencing of mRNA fragments, Ribo–seq allows to
Externí odkaz:
https://doaj.org/article/bcd4d2c74e07411eb294b762335940cb
Autor:
Anna Alvarez-Guaita, Satish Patel, Koini Lim, Afreen Haider, Liang Dong, Olivia J. Conway, Marcella K.L. Ma, Davide Chiarugi, Vladimir Saudek, Stephen O’Rahilly, David B. Savage
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108810- (2021)
Summary: Adipogenin (Adig) is an adipocyte-enriched transmembrane protein. Its expression is induced during adipogenesis in rodent cells, and a recent genome-wide association study associated body mass index (BMI)-adjusted leptin levels with the ADIG
Externí odkaz:
https://doaj.org/article/429f6fb808504b2db108fb2f69b10633
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7452 (2021)
The aim of the current study was to test the hypothesis that maternal lipid metabolism was modulated during normal pregnancy and that these modulations are altered in gestational diabetes mellitus (GDM). We tested this hypothesis using an established
Externí odkaz:
https://doaj.org/article/40ae4c69ca874432b8a1dbcb9e1ae3b1
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155028 (2016)
Pulse-chase experiments are often used to study the degradation of macromolecules such as proteins or mRNA. Considerations for the choice of pulse length include the toxicity of the pulse to the cell and maximization of labeling. In the general case
Externí odkaz:
https://doaj.org/article/b922dca8bfe740d5b8f8acb6fba7f54c
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 19, Iss Proc. FBTC 2010, Pp 116-133 (2010)
We formally characterize a set of causality-based properties of metabolic networks. This set of properties aims at making precise several notions on the production of metabolites, which are familiar in the biologists' terminology. From a theoretical
Externí odkaz:
https://doaj.org/article/d514add823be47cbb2b723de5bae7076
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 9, Pp 1801-1806 (2007)
Comparative genomics usually involves managing the functional aspects of genomes, by simply comparing gene-by-gene functions. Following this approach, Mushegian and Koonin proposed a hypothetical minimal genome, Minimal Gene Set (MGS), aiming for a p
Externí odkaz:
https://doaj.org/article/de1682b1988f4f97abd819eca51ef48f