Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Davide Vignola"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:459-461
Recent studies have highlighted a key role in regulating gene transcription, in both eukaryotes and prokaryotes, by enzymes that control the acetylation and deacetylation of histones. In particular, inhibitors of histone deacetylases (HDAC-Is) have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85ef1b1bbd19de0f2945a4d1641a96f
https://doi.org/10.1016/j.bmcl.2014.12.051
https://doi.org/10.1016/j.bmcl.2014.12.051
Autor:
Ferdinando Maria Milazzo, Walter Cabri, Silvia Rivara, Gianfranco Battistuzzi, Maurizio Taddei, Daniele Pala, Giuseppe Giannini, Marco Mor, Marcella Barbarino, Mose Santaniello, Loredana Vesci, Nicola Fanto, Davide Vignola, Mario B. Guglielmi, Claudio Pisano
A systematic study of medicinal chemistry aimed at identifying a new generation of HDAC inhibitors, through the introduction of a thiol zinc-binding group (ZBG) and of an amide-lactam in the ω-position of the polyethylene chain of the vorinostat sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463c0217af12aea0df5893d36eec877c
http://hdl.handle.net/11585/756748
http://hdl.handle.net/11585/756748
Publikováno v:
Journal of Molecular Catalysis A: Chemical. 191:1-8
Diastereomeric pure 2-(2-phenylthiophenyl)-5,6,7,8-tetrahydroquinolines were prepared and assessed in the enantioselective palladium-catalyzed allylic substitution of 1,3-diphenylprop-2-enyl acetate with dimethyl malonate and in the copper-catalyzed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2609dd4d1c15985ed79d859d7139df3
https://doi.org/10.1016/s1381-1169(02)00173-5
https://doi.org/10.1016/s1381-1169(02)00173-5
Publikováno v:
Journal of Molecular Catalysis A: Chemical. 178:27-33
Three new chiral 2,2′:6′,2″-terpyridines (terpy) were prepared from (−)-β-pinene, (+)-camphor and (+)-2-carene and the corresponding copper and rhodium complexes were assessed as chiral catalysts for the enantioselective cyclopropanation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df28deffa17af01c8b28c7d6ea4e27b5
https://doi.org/10.1016/s1381-1169(01)00287-4
https://doi.org/10.1016/s1381-1169(01)00287-4
Publikováno v:
Tetrahedron. 57:1099-1104
A number of new chiral 2,2′:6′,2″-terpyridines were prepared and the corresponding rhodium and ruthenium complexes were assessed as chiral catalysts for the enantioselective hydrosilylation of acetophenone with diphenylsilane and for the cyclop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::320b8cdbd294a1d3459e8c44eece1b89
https://doi.org/10.1016/s0040-4020(00)01082-6
https://doi.org/10.1016/s0040-4020(00)01082-6
Autor:
Luca Giannotti, Davide Vignola, Elena Cini, Gianfranco Battistuzzi, Maurizio Taddei, Giuseppe Giannini, Walter Cabri, Loredana Vesci
A series of SAHA-like molecules were prepared introducing different lactam-carboxyamides in position 7 of the suberoylanilide skeleton. The activity against different HDAC isoforms was tested and the data compared with the corresponding linear produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b28add90fc352812819fa297000a0f
http://hdl.handle.net/11365/45870
http://hdl.handle.net/11365/45870
Publikováno v:
ChemInform. 32
A number of new chiral 2,2′:6′,2″-terpyridines were prepared and the corresponding rhodium and ruthenium complexes were assessed as chiral catalysts for the enantioselective hydrosilylation of acetophenone with diphenylsilane and for the cyclop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e21d400d0d1b9b3a26e1d979811190f
https://doi.org/10.1002/chin.200123019
https://doi.org/10.1002/chin.200123019
Autor:
Marica Sassano, Davide Vignola, Vito Ruggiero, M.G. Quaglia, Giancarlo Basile, M. Pia Zibella, Rita De Santis, Mauro Semproni, Domenico Mastroianni, Andrea Ciacci, Paolo Carminati, Nicola Fanto, Valentina Bombardi, Grazia Gallo
Publikováno v:
Journal of medicinal chemistry. 51(5)
We describe the design and synthesis of a peptidomimetic library derived from the heptapeptide Ac-RDVLPGT-NH 2, belonging to the Toll/IL-1 receptor (TIR) domain of the adaptor protein MyD88 and effective in inhibiting its homodimerization. The abilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e72b0eb91724eced13456c71b007907
https://pubmed.ncbi.nlm.nih.gov/18275134
https://pubmed.ncbi.nlm.nih.gov/18275134
Autor:
Davide Vignola, Claudio Pisano, Mario B. Guglielmi, Gianfranco Battistuzzi, Marcella Barbarino, Loredana Vesci, Ferdinando Maria Milazzo, Walter Cabri, Giuseppe Giannini
Publikováno v:
Cancer Research. 73:1010-1010
Histone deacetylase inhibitors (HDACi) are one of the last frontiers in pharmaceutical research. Two HDACi are already part of armamentarium of the anticancer drugs of the oncologists: Vorinostat, Zolinza® (SAHA) and Romidepsin, Istodax® (depsipept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e239e02eda40777a74b203dad15e12ab
https://doi.org/10.1158/1538-7445.am2013-1010
https://doi.org/10.1158/1538-7445.am2013-1010
Autor:
Nicola Fantò, Grazia Gallo, Andrea Ciacci, Mauro Semproni, Davide Vignola, Marco Quaglia, Valentina Bombardi, Domenico Mastroianni, M. Pia Zibella, Giancarlo Basile, Marica Sassano, Vito Ruggiero, Rita De Santis, Paolo Carminati
Publikováno v:
Journal of Medicinal Chemistry; Feb2008, Vol. 51 Issue 5, p1189-1202, 14p