Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Davide, Vacirca"'
Autor:
Ilaria Attili, Riccardo Asnaghi, Davide Vacirca, Riccardo Adorisio, Alessandra Rappa, Alberto Ranghiero, Mariano Lombardi, Carla Corvaja, Valeria Fuorivia, Ambra Carnevale Schianca, Pamela Trillo Aliaga, Gianluca Spitaleri, Ester Del Signore, Juliana Guarize, Lorenzo Spaggiari, Elena Guerini-Rocco, Nicola Fusco, Filippo de Marinis, Antonio Passaro
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 15, p 4476 (2024)
Background: Actionable driver mutations account for 40–50% of NSCLC cases, and their identification clearly affects treatment choices and outcomes. Conversely, non-actionable mutations are genetic alterations that do not currently have established
Externí odkaz:
https://doaj.org/article/5e92df69925744f4959588ed02b29765
Autor:
Francesco Chu, Fausto Maffini, Daniela Lepanto, Davide Vacirca, Sergio Vincenzo Taormina, Rita De Berardinis, Sara Gandini, Silvano Vignati, Alberto Ranghiero, Alessandra Rappa, Susanna Chiocca, Massimo Barberis, Marta Tagliabue, Mohssen Ansarin
Publikováno v:
Cancers, Vol 15, Iss 4, p 1117 (2023)
(1) Background: The development of laryngeal cancer is a multistep process involving structural alterations of the epithelial mucosa, from dysplasia (LDy) to invasive carcinoma. In this study, we define new biomarkers, prognostic for malignant transf
Externí odkaz:
https://doaj.org/article/8c85d71396994bddbbab44dbbb767f35
Autor:
Caterina Fumagalli, Alberto Ranghiero, Sara Gandini, Federica Corso, Sergio Taormina, Elisa De Camilli, Alessandra Rappa, Davide Vacirca, Giuseppe Viale, Elena Guerini-Rocco, Massimo Barberis
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-11 (2020)
Abstract Background The breast cancer genome dynamically evolves during malignant progression and recurrence. We investigated the genomic profiles of primary early-stage breast cancers and matched relapses to elucidate the molecular underpinnings of
Externí odkaz:
https://doaj.org/article/bbd8b334048c41d1bbab7f31f4916480
Autor:
Konstantinos Venetis, Francesco Pepe, Elisabetta Munzone, Elham Sajjadi, Gianluca Russo, Pasquale Pisapia, Mariia Ivanova, Giuseppina Bonizzi, Davide Vacirca, Alessandra Rappa, Alberto Ranghiero, Sergio Vincenzo Taormina, Giuseppe Viale, Giancarlo Troncone, Massimo Barberis, Elena Guerini-Rocco, Umberto Malapelle, Nicola Fusco
Publikováno v:
Cells, Vol 11, Iss 22, p 3545 (2022)
Somatic mutations in PIK3CA are present in ~40% breast cancers (BC); their detection in hormone receptor (HR)+/HER2− tumors allows for selecting patients with advanced disease eligible for PIK3CA targeting with alpelisib. The choice of what type of
Externí odkaz:
https://doaj.org/article/57a723f8102548aca08e47928ac2cf33
Autor:
Caterina Fumagalli, Ilaria Betella, Alessandra Rappa, Maria di Giminiani, Michela Gaiano, Luigi Antonio De Vitis, Benedetta Zambetti, Davide Vacirca, Francesco Multinu, Konstantinos Venetis, Nicoletta Colombo, Massimo Barberis, Elena Guerini Rocco
Publikováno v:
Cancers, Vol 14, Iss 7, p 1638 (2022)
The establishment of PARP inhibitors in the treatment of epithelial ovarian carcinoma (EOC) has prompt BRCA assessment at the time of diagnosis. We described our five years of experience of tumor BRCA testing, as part of a multidisciplinary workflow
Externí odkaz:
https://doaj.org/article/98d699bc2b164318819c8fdd9d84d208
Autor:
Umberto Malapelle, Francesco Pepe, Pasquale Pisapia, Roberta Sgariglia, Mariantonia Nacchio, Caterina De Luca, Rosanna Lacalamita, Stefania Tommasi, Rosamaria Pinto, Grazia Palomba, Giuseppe Palmieri, Davide Vacirca, Massimo Barberis, Irene Bottillo, Paola Grammatico, Lucia Rosalba Grillo, Valerio Costa, Riccardo Smeraglio, Dario Bruzzese, Giancarlo Troncone
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Next-generation sequencing (NGS) needs to be validated and standardized to ensure that cancer patients are reliably selected for target treatments. In Italy, NGS is performed in several institutions and harmonization of wet and dry proced
Externí odkaz:
https://doaj.org/article/1fc67acac42f4a7d8cd333500eda0b27
Autor:
Caterina, Fumagalli, Ilaria, Betella, Alberto, Ranghiero, Elena, Guerini-Rocco, Giulio, Bonaldo, Alessandra, Rappa, Davide, Vacirca, Nicoletta, Colombo, Massimo, Barberis
Publikováno v:
Pathologica. 114:288-294
Background. Homologous recombination repair (HRR) is the main mechanism of repair of DNA double-strand breaks. Its deficiency (HRD) is a common feature of epithelial ovarian cancers (EOCs). BRCA1/2 mutations and/or other aberrations in genes of HRR a
Autor:
Thomas Depoilly, Simon Garinet, Léon C. van Kempen, Ed Schuuring, Sergi Clavé, Beatriz Bellosillo, Cristiana Ercolani, Simonetta Buglioni, Janna Siemanowski, Sabine Merkelbach-Bruse, Verena Tischler, Melanie-Christin Demes, Henry Paridaens, Catherine Sibille, Vincent Thomas de Montpreville, Etienne Rouleau, Artur Bartczak, Monika Pasieka-Lis, Ryan Yee Wei Teo, Khoon Leong Chuah, Marta Barbosa, Carlos Quintana, Michele Biscuola, Mercedes Delgado-Garcia, Davide Vacirca, Alessandra Rappa, Matthew Cashmore, Matthew Smith, Piotr Jasionowicz, Adam Meeney, Patrice Desmeules, Benoit Terris, Audrey Mansuet-Lupo
Publikováno v:
Journal of molecular diagnostics, 24(9), 1021-1030. ELSEVIER SCIENCE INC
Targeted therapy in lung cancer requires the assessment of multiple oncogenic driver alterations, including fusion genes. This retrospective study evaluated the Idylla GeneFusion prototype, an automated and ease-of-use (
Autor:
Marta Tagliabue, Fausto Maffini, Caterina Fumagalli, Sara Gandini, Daniela Lepanto, Federica Corso, Salvatore Cacciola, Alberto Ranghiero, Alessandra Rappa, Davide Vacirca, Maria Cossu Rocca, Daniela Alterio, Elena Guerini Rocco, Augusto Cattaneo, Francesco Chu, Stefano Zorzi, Giuseppe Curigliano, Susanna Chiocca, Massimo Barberis, Giuseppe Viale, Mohssen Ansarin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/4e233f7e17404dd29c930cd42cedca61
Autor:
Antonio Passaro, Ilaria Attili, Alessandra Rappa, Davide Vacirca, Alberto Ranghiero, Caterina Fumagalli, Juliana Guarize, Lorenzo Spaggiari, Filippo de Marinis, Massimo Barberis, Elena Guerini-Rocco
Publikováno v:
Cancers, Vol 13, Iss 9, p 2172 (2021)
An increasing number of driver genomic alterations with potential targeted treatments have been identified in non-small cell lung cancer (NSCLC). Much less is known about the incidence and different distribution of concurrent alterations, as identifi
Externí odkaz:
https://doaj.org/article/f430785801a84d27be533916c1a39c21