Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Davide, Povero"'
Autor:
Begum Aydogan Mathyk, Marshall Tabetah, Rashid Karim, Victoria Zaksas, JangKeun Kim, R. I. Anu, Masafumi Muratani, Alexia Tasoula, Ruth Subhash Singh, Yen-Kai Chen, Eliah Overbey, Jiwoon Park, Henry Cope, Hossein Fazelinia, Davide Povero, Joseph Borg, Remi V. Klotz, Min Yu, Steven L. Young, Christopher E. Mason, Nathaniel Szewczyk, Riley M. St Clair, Fathi Karouia, Afshin Beheshti
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Organismal adaptations to spaceflight have been characterized at the molecular level in model organisms, including Drosophila and C. elegans. Here, we extend molecular work to energy metabolism and sex hormone signaling in mice and humans. W
Externí odkaz:
https://doaj.org/article/d61840f0a1224eb1838b2490772d979a
Autor:
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M. Santini, Rama Pranadinata, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, James M. Veal, Gretchen Bain, Erwin W. Gelfand
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The NLRP3 inflammasome is an intracellular, multiprotein complex that promotes the auto-catalytic activation of caspase-1 and the subsequent maturation and secretion of the pro-inflammatory cytokines, IL-1β and IL-18. Persistent activation
Externí odkaz:
https://doaj.org/article/a9366cea20b64379ae3b798f5d428a2d
Autor:
Akiko Eguchi, Motoh Iwasa, Ryosuke Sugimoto, Mina Tempaku, Kyoko Yoshikawa, Naohiko Yoshizawa, Davide Povero, Kazushi Sugimoto, Hiroshi Hasegawa, Yoshiyuki Takei, Hayato Nakagawa
Publikováno v:
Hepatology Communications, Vol 6, Iss 12, Pp 3515-3527 (2022)
Abstract Complement complex 1 subunit q (C1q) has multiple functions, including cell migration, in addition to its traditional complement‐activating effect. Research shows C1q is a ligand for frizzled receptors (FZDs). FZD‐induced yes‐associate
Externí odkaz:
https://doaj.org/article/f777e468e1c34e10996bb4629e88fc8c
Autor:
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M. Santini, Rama Pranadinata, Casey D. Johnson, Matthew D. McGeough, Federico C. Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M. Hoffman, Ariel E. Feldstein, Jeffrey A. Stafford, James M. Veal, Gretchen Bain, Erwin W. Gelfand
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/71601d03ca0a42d8941718d51407d3e9
Autor:
Aleksandra Leszczynska, Christian Stoess, Hana Sung, Davide Povero, Akiko Eguchi, Ariel Feldstein
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2808 (2023)
Chronic liver diseases can lead to fibrotic changes that may progress to the development of cirrhosis, which poses a significant risk for morbidity and increased mortality rates. Metabolic dysfunction-associated steatotic liver disease (MASLD), alcoh
Externí odkaz:
https://doaj.org/article/4d5343623b1a46c9b5d3d2200d1e81a6
Autor:
Davide Povero, Masahiko Tameda, Akiko Eguchi, Wenhua Ren, Jihoon Kim, Robert Myers, Zachary D. Goodman, Stephen A. Harrison, Arun J. Sanyal, Jaime Bosch, Lucila Ohno-Machado, Ariel E. Feldstein
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Primary sclerosing cholangitis (PSC) is an idiopathic and heterogenous cholestatic liver disease characterized by chronic inflammation and fibrosis of the biliary tree. Currently, no effective therapies are available for this condition, whos
Externí odkaz:
https://doaj.org/article/f7dd9db4292b4f9fb959aa9ca0e2edfd
Characterization and Proteome of Circulating Extracellular Vesicles as Potential Biomarkers for NASH
Autor:
Davide Povero, Hirokazu Yamashita, Wenhua Ren, Mani G. Subramanian, Robert P. Myers, Akiko Eguchi, Douglas A. Simonetto, Zachary D. Goodman, Stephen A. Harrison, Arun J. Sanyal, Jaime Bosch, Ariel E. Feldstein
Publikováno v:
Hepatology Communications, Vol 4, Iss 9, Pp 1263-1278 (2020)
Nonalcoholic fatty liver disease (NAFLD) is currently one of most common forms of chronic liver disease globally. NAFLD represents a wide spectrum of liver involvement from nonprogressive isolated steatosis to nonalcoholic steatohepatitis (NASH), cha
Externí odkaz:
https://doaj.org/article/1c5852d739384f4da18fdbdf5bc6bffd
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide. A significant proportion of patients with NAFLD develop a progressive inflammatory condition termed nonalcoholic steatohepatitis (NASH), which may ev
Externí odkaz:
https://doaj.org/article/c3617032d0ad4f18981080bbab3a4389
Autor:
Christopher McBride, Lynnie Trzoss, Davide Povero, Milos Lazic, Geza Ambrus-Aikelin, Angelina Santini, Rama Pranadinata, Gretchen Bain, Ryan Stansfield, Jeffrey A. Stafford, James Veal, Ryan Takahashi, Justin Ly, Shu Chen, Liling Liu, Marika Nespi, Robert Blake, Arna Katewa, Tracy Kleinheinz, Swathi Sujatha-Bhaskar, Nandhini Ramamoorthi, Jessica Sims, Brent McKenzie, Mark Chen, Mark Ultsch, Matthew Johnson, Jeremy Murray, Claudio Ciferri, Steven T. Staben, Michael J. Townsend, Craig E. Stivala
Publikováno v:
Journal of Medicinal Chemistry. 65:14721-14739
Autor:
Davide Povero, Yongbin Chen, Scott M. Johnson, Cailin E. McMahon, Meixia Pan, Hanmei Bao, Xuan-Mai T. Petterson, Emily Blake, Kimberly P. Lauer, Daniel R. O’Brien, Yue Yu, Rondell P. Graham, Timucin Taner, Xianlin Han, Gina L. Razidlo, Jun Liu
Publikováno v:
Journal of Hepatology.