Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Davide, Pellacani"'
Autor:
Kathryn Westendorf, Stefanie Žentelis, Lingshu Wang, Denisa Foster, Peter Vaillancourt, Matthew Wiggin, Erica Lovett, Robin van der Lee, Jörg Hendle, Anna Pustilnik, J. Michael Sauder, Lucas Kraft, Yuri Hwang, Robert W. Siegel, Jinbiao Chen, Beverly A. Heinz, Richard E. Higgs, Nicole L. Kallewaard, Kevin Jepson, Rodrigo Goya, Maia A. Smith, David W. Collins, Davide Pellacani, Ping Xiang, Valentine de Puyraimond, Marketa Ricicova, Lindsay Devorkin, Caitlin Pritchard, Aoise O’Neill, Kush Dalal, Pankaj Panwar, Harveer Dhupar, Fabian A. Garces, Courtney A. Cohen, John M. Dye, Kathleen E. Huie, Catherine V. Badger, Darwyn Kobasa, Jonathan Audet, Joshua J. Freitas, Saleema Hassanali, Ina Hughes, Luis Munoz, Holly C. Palma, Bharathi Ramamurthy, Robert W. Cross, Thomas W. Geisbert, Vineet Menachery, Kumari Lokugamage, Viktoriya Borisevich, Iliana Lanz, Lisa Anderson, Payal Sipahimalani, Kizzmekia S. Corbett, Eun Sung Yang, Yi Zhang, Wei Shi, Tongqing Zhou, Misook Choe, John Misasi, Peter D. Kwong, Nancy J. Sullivan, Barney S. Graham, Tara L. Fernandez, Carl L. Hansen, Ester Falconer, John R. Mascola, Bryan E. Jones, Bryan C. Barnhart
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110812- (2022)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 (COVID-19) when administered early. However, SARS-CoV-2 variants of c
Externí odkaz:
https://doaj.org/article/daeff3ff2f814504a3643f35bb419fcf
Publikováno v:
Cell Reports, Vol 21, Iss 4, Pp 1116-1126 (2017)
Summary: The normal adult human female mammary gland is a bilayered structure consisting of an outer basal layer and two readily distinguished subsets of cells within the inner luminal layer. We now present a validated methodology for undertaking lar
Externí odkaz:
https://doaj.org/article/3d9faa0cfeb54674be8e60187f23391f
Autor:
Martin Hirst, Shane Colborne, Connie J. Eaves, Davide Pellacani, Gregg B. Morin, Amal El-Naggar, Gian Luca Negri, Sylvain Lefort, Susanna Tan, Barry A. Gusterson, Poul H. Sorensen
Publikováno v:
Cell Death and Differentiation
Breast cancer heterogeneity has made it challenging to identify mechanisms critical to the initial stages of their genesis in vivo. Here, we sought to interrogate the role of YB-1 in newly arising human breast cancers as well as in established cell l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b65ce69685b8e25437a102822aa56c
https://doi.org/10.1038/s41418-021-00836-6
https://doi.org/10.1038/s41418-021-00836-6
Autor:
Jayant K. Rane, Alastair P. Droop, Davide Pellacani, Euan S. Polson, Matthew S. Simms, Anne T. Collins, Leo S.D. Caves, Norman J. Maitland
Publikováno v:
Stem Cell Reports, Vol 2, Iss 2, Pp 180-188 (2014)
Human epithelia are organized in a hierarchical structure, where stem cells generate terminally differentiated cells via intermediate progenitors. This two-step differentiation process is conserved in all tissues, but it is not known whether a common
Externí odkaz:
https://doaj.org/article/224cf99a347c42e9aa68aa3823822cce
Autor:
Ankit Sinha, Hyeyeon Kim, Jennifer Cruickshank, Mina Alam, Marianne Koritzinsky, Mar Garcia-Valero, Curtis W McCloskey, Rama Khokha, Ravi N. Vellanki, Mathepan Mahendralingam, Luis Palomero, Vid Stambolic, Alison E. Casey, Ronak Shetty, Aaron D. Schimmer, Pirashaanthy Tharmapalan, Miquel Angel Pujana, Davide Pellacani, Vladimir Ignatchenko, Connie J. Eaves, Thomas Kislinger, Kazeera Aliar, Hal K. Berman
Publikováno v:
Nature Metabolism. 3:665-681
Cancer metabolism adapts the metabolic network of its tissue of origin. However, breast cancer is not a disease of a single origin. Multiple epithelial populations serve as the culprit cell of origin for specific breast cancer subtypes, yet our knowl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128d5b18c50fd5f6a54858eab3c70551
https://doi.org/10.1038/s42255-021-00388-6
https://doi.org/10.1038/s42255-021-00388-6
Autor:
Sylvain Lefort, Poul H. Sorensen, Bo Rafn, Susanna Tan, Connie J. Eaves, Martin Hirst, Davide Pellacani, Sneha Balani
Publikováno v:
Oncogene
High YAP activity is associated with poor prognosis human breast cancers, but its role during the initial stage of mammary cell transformation is unknown. To address this question, we designed experiments that exploit the ability of KRASG12D-transduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eae30d45cd6871425dc076f4af58720
https://doi.org/10.1038/s41388-019-1111-0
https://doi.org/10.1038/s41388-019-1111-0
Autor:
Garry P. Nolan, Sean C. Bendall, Carl L. Hansen, Connie J. Eaves, Fangwu Wang, Michael VanInsberghe, Colin A. Hammond, Paul H. Miller, Davide Pellacani, Nima Aghaeepour, Philip A. Beer, David J.H.F. Knapp
Publikováno v:
Blood. 133:927-939
Recent advances in single-cell molecular analytical methods and clonal growth assays are enabling more refined models of human hematopoietic lineage restriction processes to be conceptualized. Here, we report the results of integrating single-cell pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15fcce0c1303eea8c8f18302eaa1affd
https://doi.org/10.1182/blood-2018-10-878025
https://doi.org/10.1182/blood-2018-10-878025
Autor:
Kathryn Westendorf, Stefanie Žentelis, Lingshu Wang, Denisa Foster, Peter Vaillancourt, Matthew Wiggin, Erica Lovett, Robin van der Lee, Jörg Hendle, Anna Pustilnik, J. Michael Sauder, Lucas Kraft, Yuri Hwang, Robert W. Siegel, Jinbiao Chen, Beverly A. Heinz, Richard E. Higgs, Nicole L. Kallewaard, Kevin Jepson, Rodrigo Goya, Maia A. Smith, David W. Collins, Davide Pellacani, Ping Xiang, Valentine de Puyraimond, Marketa Ricicova, Lindsay Devorkin, Caitlin Pritchard, Aoise O’Neill, Kush Dalal, Pankaj Panwar, Harveer Dhupar, Fabian A. Garces, Courtney A. Cohen, John M. Dye, Kathleen E. Huie, Catherine V. Badger, Darwyn Kobasa, Jonathan Audet, Joshua J. Freitas, Saleema Hassanali, Ina Hughes, Luis Munoz, Holly C. Palma, Bharathi Ramamurthy, Robert W. Cross, Thomas W. Geisbert, Vineet Menacherry, Kumari Lokugamage, Viktoriya Borisevich, Iliana Lanz, Lisa Anderson, Payal Sipahimalani, Kizzmekia S. Corbett, Eun Sung Yang, Yi Zhang, Wei Shi, Tongqing Zhou, Misook Choe, John Misasi, Peter D. Kwong, Nancy J. Sullivan, Barney S. Graham, Tara L. Fernandez, Carl L. Hansen, Ester Falconer, John R. Mascola, Bryan E. Jones, Bryan C. Barnhart
Publikováno v:
bioRxiv
SARS-CoV-2 neutralizing monoclonal antibodies (mAbs) can reduce the risk of hospitalization when administered early during COVID-19 disease. However, the emergence of variants of concern has negatively impacted the therapeutic use of some authorized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb8cf2c168e04af64aeb77ae8c382f6
https://europepmc.org/articles/PMC8109210/
https://europepmc.org/articles/PMC8109210/
Autor:
Engin Ulukaya, Fiona M Frame, Buse Cevatemre, Davide Pellacani, Hannah Walker, Vincent M Mann, Matthew S Simms, Michael J Stower, Veysel T Yilmaz, Norman J Maitland
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64278 (2013)
The outcome for patients with advanced metastatic and recurrent prostate cancer is still poor. Therefore, new chemotherapeutics are required, especially for killing cancer stem cells that are thought to be responsible for disease recurrence. In this
Externí odkaz:
https://doaj.org/article/fa2ab04b61094a7daa200d16cc8d7ccd
Autor:
Sylvain Lefort, Véronique Maguer-Satta, Sneha Balani, Sharon M. Gorski, Davide Pellacani, Boris Guyot, Connie J. Eaves
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-77347-w⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-77347-w⟩
Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-77347-w⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, 2020, 10 (1), ⟨10.1038/s41598-020-77347-w⟩
Assessment of autophagy activity has historically been limited to investigations of fixed tissue or bulk cell populations. To address questions of heterogeneity and relate measurements to functional properties of viable cells isolated from primary ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cb096421ad3aae9958f01d4251b359
https://hal.archives-ouvertes.fr/hal-03040464/document
https://hal.archives-ouvertes.fr/hal-03040464/document