Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Davide, Marenduzzo"'
Publikováno v:
Physical Review Research, Vol 3, Iss 4, p 043070 (2021)
Topological entanglements are abundant, and often detrimental, in polymeric systems in biology and materials science. Here we theoretically investigate the topological simplification of knots by diffusing slip-links (SLs), which may represent biologi
Externí odkaz:
https://doaj.org/article/0474545bd60943e7a5cf238b468d57bc
Autor:
Michael Chiang, Davide Michieletto, Chris A. Brackley, Nattaphong Rattanavirotkul, Hisham Mohammed, Davide Marenduzzo, Tamir Chandra
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3212-3223.e6 (2019)
Summary: Lamina-associated domains (LADs) cover a large part of the human genome and are thought to play a major role in shaping the nuclear architectural landscape. Here, we perform polymer simulations, microscopy, and mass spectrometry to dissect t
Externí odkaz:
https://doaj.org/article/b3bd1b48ebd04c8aab0d737c668e05f9
Autor:
Lilija Brant, Theodore Georgomanolis, Milos Nikolic, Chris A Brackley, Petros Kolovos, Wilfred van Ijcken, Frank G Grosveld, Davide Marenduzzo, Argyris Papantonis
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 12, Pp 1-8 (2016)
Abstract Mammalian interphase chromosomes fold into a multitude of loops to fit the confines of cell nuclei, and looping is tightly linked to regulated function. Chromosome conformation capture (3C) technology has significantly advanced our understan
Externí odkaz:
https://doaj.org/article/2e4769f6383046958f190470f85f6feb
Publikováno v:
Physical Review X, Vol 10, Iss 3, p 031059 (2020)
Active matter exhibits various forms of nonequilibrium states in the absence of external forcing, including macroscopic steady-state currents. Such states are often too complex to be modeled from first principles, and our understanding of their physi
Externí odkaz:
https://doaj.org/article/7d149781a8134d65997488cae59d1bb9
Autor:
Iain Muntz, Franceska Waggett, Michael Hunter, Andrew B. Schofield, Paul Bartlett, Davide Marenduzzo, Job H. J. Thijssen
Publikováno v:
Physical Review Research, Vol 2, Iss 2, p 023388 (2020)
We show that the interaction potential between sterically stabilized, nearly hard-sphere [poly(methyl methacrylate)–poly(lauryl methacrylate) (PMMA-PLMA)] colloids at a water-oil interface has a negligible unscreened-dipole contribution, suggesting
Externí odkaz:
https://doaj.org/article/eeb0bbc53b564566babd2dd8415295a1
Publikováno v:
Bonato, A, Marenduzzo, D, Michieletto, D & Orlandini, E 2022, ' Topological gelation of reconnecting polymers ', Proceedings of the National Academy of Sciences (PNAS), vol. 119, no. 44, e2207728119, pp. 1-8 . https://doi.org/10.1073/pnas.2207728119
DNA recombination is a ubiquitous process that ensures genetic diversity. Contrary to textbook pictures, DNA recombination, as well as generic DNA translocations, occur in a confined and highly entangled environment. Inspired by this observation, her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbf5fcc4920a07ee70eaca3ea79ef1b
https://hdl.handle.net/20.500.11820/e32f7408-1329-4ced-a2f8-ee6eb62b8f74
https://hdl.handle.net/20.500.11820/e32f7408-1329-4ced-a2f8-ee6eb62b8f74
We study the phase behaviour of cholesteric liquid crystal shells with different geometries. We compare the cases of tangential and no anchoring at the surface, focussing on the former case, which leads to a competition between the intrinsic tendency
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676752292deb71500755ca8a8abbe42f
http://arxiv.org/abs/2210.04877
http://arxiv.org/abs/2210.04877
SUMMARYEukaryotic chromosomes compact during mitosis and meiosis into elongated cylinders – and not the spherical globules expected of self-attracting long flexible polymers. This process is mainly driven by condensin-like proteins. Here, we presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48fdd3187d308c025941588135927ad0
https://doi.org/10.1101/2022.09.27.509716
https://doi.org/10.1101/2022.09.27.509716
Autor:
Carlos Sacristan, Kumiko Samejima, Lorena Andrade Ruiz, Maaike L.A. Lambers, Adam Buckle, Chris A. Brackley, Daniel Robertson, Tetsuya Hori, Shaun Webb, Tatsuo Fukagawa, Nick Gilbert, Davide Marenduzzo, William C. Earnshaw, Geert J.P.L. Kops
The Structural Maintenance of Chromosomes (SMC) complexes cohesin and condensin establish the 3D organization of mitotic chromosomes1–3. Cohesin is essential to maintain sister chromatid pairing until anaphase onset4, while condensin is important f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42bbd9efc935406e689cfb25d5cefd80
https://doi.org/10.1101/2022.08.01.502248
https://doi.org/10.1101/2022.08.01.502248
Autor:
Michael Chiang, Chris A. Brackley, Catherine Naughton, Ryu-Suke Nozawa, Cleis Battaglia, Davide Marenduzzo, Nick Gilbert
Classical observations have long suggested there is a link between 3D gene structure and transcription1–4. However, due to the many factors regulating gene expression, and to the challenge of visualizing DNA and chromatin dynamics at the same time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc270d80b820d3328f5dc20306a0816e
https://doi.org/10.1101/2022.06.09.495447
https://doi.org/10.1101/2022.06.09.495447