Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Davide, Comoletti"'
Autor:
M. Dolores Martín-De-Saavedra, Marc Dos Santos, Lorenza Culotta, Olga Varea, Benjamin Spielman, Euan Parnell, Davide Comoletti, Stefan Lichtenthaler, Jeffrey Burgdorf, Maria Barbolina, Jeffrey Savas, Peter Penzes
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S52- (2023)
Externí odkaz:
https://doaj.org/article/2114aa5fa36940e1b412af605baae9cc
Autor:
Theresa E. Pankhurst, Kaitlin H. Buick, Joshua L. Lange, Andrew J. Marshall, Kaileen R. Button, Olga R. Palmer, Kathryn J. Farrand, Isabelle Montgomerie, Thomas W. Bird, Ngarangi C. Mason, Joanna Kuang, Benjamin J. Compton, Davide Comoletti, Mariolina Salio, Vincenzo Cerundolo, Miguel E. Quiñones-Mateu, Gavin F. Painter, Ian F. Hermans, Lisa M. Connor
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112310- (2023)
Summary: Protective immune responses against respiratory pathogens, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza virus, are initiated by the mucosal immune system. However, most licensed vaccines are administered
Externí odkaz:
https://doaj.org/article/a3b5f150bb494cd2ab24b2e9cd902159
Autor:
Nuno Apóstolo, Samuel N. Smukowski, Jeroen Vanderlinden, Giuseppe Condomitti, Vasily Rybakin, Jolijn ten Bos, Laura Trobiani, Sybren Portegies, Kristel M. Vennekens, Natalia V. Gounko, Davide Comoletti, Keimpe D. Wierda, Jeffrey N. Savas, Joris de Wit
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Mossy fiber synapses are key in CA3 microcircuit function. Here, the authors profile the mossy fiber synapse proteome and cell-surface interactome. They uncover a diverse repertoire of cell-surface proteins and identify the receptor IgSF8 as a regula
Externí odkaz:
https://doaj.org/article/73f057183b374a89915c293d2ed3556b
Autor:
Ciara Bagnall-Moreau, Patricio T. Huerta, Davide Comoletti, Andrea La-Bella, Roseann Berlin, Chunfang Zhao, Bruce T. Volpe, Betty Diamond, Lior Brimberg
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract The concept that exposure in utero to maternal anti-brain antibodies contributes to the development of autism spectrum disorders (ASD) has been entertained for over a decade. We determined that antibodies targeting Caspr2 are present at high
Externí odkaz:
https://doaj.org/article/0d79b86102654d0993d2e8b06b7ea1de
Autor:
Verity A. Jackson, Shahid Mehmood, Matthieu Chavent, Pietro Roversi, Maria Carrasquero, Daniel del Toro, Goenuel Seyit-Bremer, Fanomezana M. Ranaivoson, Davide Comoletti, Mark S. P. Sansom, Carol V. Robinson, Rüdiger Klein, Elena Seiradake
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
FLRT proteins are known to interact with Lphns and Unc5s, mediating cell adhesion and repulsion respectively. Here the authors use crystallography, native mass spectrometry, molecular dynamics simulations and cell-based assays to show that these thre
Externí odkaz:
https://doaj.org/article/ef384409442e4b9a8531b5fb0fc42da1
Autor:
Le Wang, Vincent R. Mirabella, Rujia Dai, Xiao Su, Ranjie Xu, Azadeh Jadali, Matteo Bernabucci, Ishnoor Singh, Yu Chen, Jianghua Tian, Peng Jiang, Kevin Y. Kwan, ChangHui Pak, Chunyu Liu, Davide Comoletti, Ronald P. Hart, Chao Chen, Thomas C. Südhof, Zhiping P. Pang
Publikováno v:
Molecular Psychiatry.
Mutations in many synaptic genes are associated with autism spectrum disorders (ASDs), suggesting that synaptic dysfunction is a key driver of ASD pathogenesis. Among these mutations, the R451C-substitution in the NLGN3 gene that encodes the postsyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7d16301586fb64023514cc96ad2d4a
https://doi.org/10.1038/s41380-022-01834-x
https://doi.org/10.1038/s41380-022-01834-x
Autor:
Onno Akkermans, Céline Delloye-Bourgeois, Claudia Peregrina, Maria Carrasquero-Ordaz, Maria Kokolaki, Miguel Berbeira-Santana, Matthieu Chavent, Florie Reynaud, Ritu Raj, Jon Agirre, Metin Aksu, Eleanor S. White, Edward Lowe, Dounia Ben Amar, Sofia Zaballa, Jiandong Huo, Irene Pakos, Patrick T.N. McCubbin, Davide Comoletti, Raymond J. Owens, Carol V. Robinson, Valérie Castellani, Daniel del Toro, Elena Seiradake
Neural migration is a critical step during brain development that requires the interactions of cell-surface guidance receptors. Cancer cells often hijack these mechanisms to disseminate. Here, we reveal crystal structures of Uncoordinated-5 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f639c2764fd0c039883a39c5c74777
https://doi.org/10.1016/j.cell.2022.09.025
https://doi.org/10.1016/j.cell.2022.09.025
Autor:
Isabelle Montgomerie, Thomas W. Bird, Olga R. Palmer, Ngarangi C. Mason, Theresa E. Pankhurst, Blair Lawley, Leonor C. Hernández, Rhodri Harfoot, Astrid Authier-Hall, Danielle E. Anderson, Kerry L. Hilligan, Kaitlin H. Buick, Naasson M. Mbenza, Gerd Mittelstädt, Samara Maxwell, Shubhra Sinha, Joanna Kuang, Kanta Subbarao, Emily J. Parker, Alan Sher, Ian F. Hermans, James E. Ussher, Miguel E. Quiñones-Mateu, Davide Comoletti, Lisa M. Connor
Publikováno v:
iScience. 26:106256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::566f669f68ea55d421658b5c1a9a169d
https://doi.org/10.1016/j.isci.2023.106256
https://doi.org/10.1016/j.isci.2023.106256
Autor:
Theresa E. Pankhurst, Kaitlin H. Buick, Joshua L. Lange, Andrew J. Marshall, Kaileen R. Button, Olga R. Palmer, Kathryn J. Farrand, Isabelle F. N. Stewart, Thomas Bird, Ngarangi C. Mason, Benjamin J. Compton, Davide Comoletti, Mariolina Salio, Vincenzo Cerundolo, Gavin F. Painter, Ian F. Hermans, Lisa M. Connor
Protective immune responses against respiratory pathogens, including influenza virus are initiated by the mucosal immune system. However, most licensed vaccines are administered parenterally and are largely ineffective at inducing mucosal immunity. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffc59a893b8bcba39f1cb73bb5d6cef0
https://doi.org/10.1101/2022.03.31.486638
https://doi.org/10.1101/2022.03.31.486638
Publikováno v:
European Biophysics Journal
Reelin is a secreted glycoprotein that is integral in neocortex development and synaptic function. Reelin exists as a homodimer with two chains linked by a disulfide bond at cysteine 2101, a feature that is vital to the protein’s function. This is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbac3e6e5f8973d706a1c30cc4b32bba
https://doi.org/10.1007/s00249-020-01465-6
https://doi.org/10.1007/s00249-020-01465-6