Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Davide, Cirillo"'
Autor:
Iker Núñez-Carpintero, Maria Rigau, Mattia Bosio, Emily O’Connor, Sally Spendiff, Yoshiteru Azuma, Ana Topf, Rachel Thompson, Peter A. C. ’t Hoen, Teodora Chamova, Ivailo Tournev, Velina Guergueltcheva, Steven Laurie, Sergi Beltran, Salvador Capella-Gutiérrez, Davide Cirillo, Hanns Lochmüller, Alfonso Valencia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Exploring the molecular basis of disease severity in rare disease scenarios is a challenging task provided the limitations on data availability. Causative genes have been described for Congenital Myasthenic Syndromes (CMS), a group of divers
Externí odkaz:
https://doaj.org/article/da340b3b30af42679f99a2df69ba8241
Autor:
Alexandros Armaos, François Serra, Iker Núñez-Carpintero, Ji-Heui Seo, Sylvan C. Baca, Stefano Gustincich, Alfonso Valencia, Matthew L. Freedman, Davide Cirillo, Claudia Giambartolomei, Gian Gaetano Tartaglia
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract We introduce Promoter-Enhancer-Guided Interaction Networks (PENGUIN), a method for studying protein-protein interaction (PPI) networks within enhancer-promoter interactions. PENGUIN integrates H3K27ac-HiChIP data with tissue-specific PPIs to
Externí odkaz:
https://doaj.org/article/077f61bbaa3e4111ae79177f5ac440ca
Autor:
Pablo Velasco, Francisco Bautista, Alba Rubio, Yurena Aguilar, Susana Rives, Jose L. Dapena, Antonio Pérez, Manuel Ramirez, Cristina Saiz-Ladera, Elisa Izquierdo, Adela Escudero, Mireia Camós, Nerea Vega-García, Margarita Ortega, Gloria Hidalgo-Gómez, Carlos Palacio, Pablo Menéndez, Clara Bueno, Joan Montero, Paola A. Romecín, Santiago Zazo, Federico Alvarez, Juan Parras, Carmen Ortega-Sabater, Salvador Chulián, María Rosa, Davide Cirillo, Elena García, Jorge García, Albert Manzano-Muñoz, Alfredo Minguela, Jose L. Fuster
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with survival rates exceeding 85%. However, 15% of patients will relapse; consequently, their survival rates decrease to below 50%. Therefore, several research and innovation stu
Externí odkaz:
https://doaj.org/article/5124b9f3d98a4c79a13549557a869a45
Publikováno v:
Frontiers in Global Women's Health, Vol 4 (2023)
Historically, biomedical research has been led by and focused on men. The recent introduction of Artificial Intelligence (AI) in this area has further proven this practice to be discriminatory for other sexes and genders, more noticeably for women. T
Externí odkaz:
https://doaj.org/article/5eec88cc910146469e2223b63b85fbe2
Autor:
Miguel Ponce-de-Leon, Javier del Valle, José María Fernandez, Marc Bernardo, Davide Cirillo, Jon Sanchez-Valle, Matthew Smith, Salvador Capella-Gutierrez, Tania Gullón, Alfonso Valencia
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-16 (2021)
Measurement(s) COVID-19 cases • mobility • population Technology Type(s) Real Time PCR • mobile phone Sample Characteristic - Organism Homo sapiens • Severe acute respiratory syndrome-related coronavirus Sample Characteristic - Location Kingd
Externí odkaz:
https://doaj.org/article/7b7428bf61a445bc8f039711f44ff2d9
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 817-829 (2021)
From genome‐scale experimental studies to imaging data, behavioral footprints, and longitudinal healthcare records, the convergence of big data in cancer research and the advances in Artificial Intelligence (AI) is paving the way to develop a syste
Externí odkaz:
https://doaj.org/article/074910ccb2b049c48a0464d0f330f82f
Autor:
Alberto Ferrari, Enrico Santus, Davide Cirillo, Miguel Ponce-de-Leon, Nicola Marino, Maria Teresa Ferretti, Antonella Santuccione Chadha, Nikolaos Mavridis, Alfonso Valencia
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-8 (2021)
Abstract Targeted contact-tracing through mobile phone apps has been proposed as an instrument to help contain the spread of COVID-19 and manage the lifting of nation-wide lock-downs currently in place in USA and Europe. However, there is an ongoing
Externí odkaz:
https://doaj.org/article/1dd0165ab9d2495b8cccf21a610df530
Autor:
Davide Cirillo, Silvina Catuara-Solarz, Czuee Morey, Emre Guney, Laia Subirats, Simona Mellino, Annalisa Gigante, Alfonso Valencia, María José Rementeria, Antonella Santuccione Chadha, Nikolaos Mavridis
Publikováno v:
npj Digital Medicine, Vol 3, Iss 1, Pp 1-11 (2020)
Abstract Precision Medicine implies a deep understanding of inter-individual differences in health and disease that are due to genetic and environmental factors. To acquire such understanding there is a need for the implementation of different types
Externí odkaz:
https://doaj.org/article/a828eca8fdeb4d18a319bb90784a8994
Autor:
Shahin Sarowar, Davide Cirillo, Pablo Játiva, Mette Hartmark Nilsen, Sarah-Muheha Anni Otragane, Jan Heggdal, Frode Selheim, Valentín Ceña, Hans-René Bjørsvik, Per Øyvind Enger
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Metastatic tumors with moderate radiosensitivity account for most cancer-related deaths, highlighting the limitations of current radiotherapy regimens. The xCT-inhibitor sulfasalazine (SAS) sensitizes cancer cells to radiotherapy by blocking cystine
Externí odkaz:
https://doaj.org/article/dd9a9a4b0be142ba87cf11186be1469d
Autor:
Carlo Matera, Michael Kauk, Davide Cirillo, Marco Maspero, Claudio Papotto, Daniela Volpato, Ulrike Holzgrabe, Marco De Amici, Carsten Hoffmann, Clelia Dallanoce
Publikováno v:
Molecules, Vol 28, Iss 5, p 2407 (2023)
In the last few years, fluorescence resonance energy transfer (FRET) receptor sensors have contributed to the understanding of GPCR ligand binding and functional activation. FRET sensors based on muscarinic acetylcholine receptors (mAChRs) have been
Externí odkaz:
https://doaj.org/article/448640a720154459b4d602372ed6bc63