Zobrazeno 1 - 10
of 15
pro vyhledávání: '"David van Zessen"'
Autor:
Pauline van Schouwenburg, Susanne Unger, Kathryn J. Payne, Fabian M. P. Kaiser, Ingrid Pico-Knijnenburg, Jens Pfeiffer, Oliver Hausmann, David Friedmann, Michelle Erbel, Maximilian Seidl, David van Zessen, Andrew P. Stubbs, Mirjam van der Burg, Klaus Warnatz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Common variable immunodeficiency (CVID), characterized by recurrent infections, low serum class-switched immunoglobulin isotypes, and poor antigen-specific antibody responses, comprises a heterogeneous patient population in terms of clinical presenta
Externí odkaz:
https://doaj.org/article/003fd5f0403547f692216d98a57c9ffd
Autor:
Pauline A. van Schouwenburg, Hanna IJspeert, Ingrid Pico-Knijnenburg, Virgil A. S. H. Dalm, P. Martin van Hagen, David van Zessen, Andrew P. Stubbs, Smita Y. Patel, Mirjam van der Burg
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Common variable immune deficiency disorder (CVID) is the most clinically relevant cause of antibody failure. It is a highly heterogeneous disease with different underlying etiologies. CVID has been associated with a quantitative B cell defect, howeve
Externí odkaz:
https://doaj.org/article/e6d89f4f38df4d03befd245ad4c51274
Autor:
Prisca M.J. Theunissen, David van Zessen, Andrew P. Stubbs, Malek Faham, Christian M. Zwaan, Jacques J.M. van Dongen, Vincent H.J. Van Der Velden
Publikováno v:
Haematologica, Vol 102, Iss 11 (2017)
In B-cell precursor acute lymphoblastic leukemia, the initial leukemic cells share the same antigen receptor gene rearrangements. However, due to ongoing rearrangement processes, leukemic cells with different gene rearrangement patterns can develop,
Externí odkaz:
https://doaj.org/article/e34f4e8107b84824a566853750a2331f
Autor:
Hanna IJspeert, Pauline A. van Schouwenburg, David van Zessen, Ingrid Pico-Knijnenburg, Gertjan J. Driessen, Andrew P. Stubbs, Mirjam van der Burg
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Upon antigen recognition via their B cell receptor (BR) B cells migrate to the germinal center where they undergo somatic hypermutation (SHM) to increase their affinity for the antigen, and class switch recombination (CSR) to change the effector func
Externí odkaz:
https://doaj.org/article/f216c4ec23b64e45a1e63ac5395695e2
Autor:
David van Zessen, Prisca M J Theunissen, Malek Faham, Jacques J.M. van Dongen, Vincent H.J. van der Velden, Andrew P. Stubbs, Christian M. Zwaan
Publikováno v:
Haematologica, 102(11), 1869-1877. Ferrata Storti Foundation
Haematologica
Haematologica
In B-cell precursor acute lymphoblastic leukemia, the initial leukemic cells share the same antigen receptor gene rearrangements. However, due to ongoing rearrangement processes, leukemic cells with different gene rearrangement patterns can develop,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a914b344c948b9fd58e6d49797535447
https://doi.org/10.3324/haematol.2017.171454
https://doi.org/10.3324/haematol.2017.171454
Autor:
David van Zessen, Hanna IJspeert, Andrew P. Stubbs, Ingrid Pico-Knijnenburg, Pauline A. van Schouwenburg, Mirjam van der Burg
Publikováno v:
Journal of Immunology, 198(10), 4156-4165. American Association of Immunologists
Antigen Receptor Galaxy (ARGalaxy) is a Web-based tool for analyses and visualization of TCR and BCR sequencing data of 13 species. ARGalaxy consists of four parts: the demultiplex tool, the international ImMunoGeneTics information system (IMGT) conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f135b240c8fc08316cd3c72b005850
https://doi.org/10.4049/jimmunol.1601921
https://doi.org/10.4049/jimmunol.1601921
Autor:
Pauline A. van Schouwenburg, Hanna IJspeert, Ingrid Pico-Knijnenburg, Virgil A. S. H. Dalm, P. Martin van Hagen, David van Zessen, Andrew P. Stubbs, Smita Y. Patel, Mirjam van der Burg
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9:2545. Frontiers Media S.A.
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, 9:2545. Frontiers Media S.A.
Common variable immune deficiency disorder (CVID) is the most clinically relevant cause of antibody failure. It is a highly heterogeneous disease with different underlying etiologies. CVID has been associated with a quantitative B cell defect, howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069b136b4a14d84524ed9fe886d13b49
https://ora.ox.ac.uk/objects/uuid:8e4fda85-a471-4f89-8b4e-0dd7a5a1ac0c
https://ora.ox.ac.uk/objects/uuid:8e4fda85-a471-4f89-8b4e-0dd7a5a1ac0c
Autor:
Peter van Baarlen, David van Zessen, Michiel Kleerebezem, Marcela M Fernandez-Gutierrez, Andrew P. Stubbs, P.P.J. Roosjen, Jerry M. Wells
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7915d3a37e0ddf53e91d0cc78456ac86
https://doi.org/10.1038/protex.2019.015
https://doi.org/10.1038/protex.2019.015
Autor:
Prisca M J Theunissen, Valerie de Haas, Vincent H.J. van der Velden, Andrew P. Stubbs, David van Zessen, Maaike de Bie
Publikováno v:
Leukemia Research, 76, 98-104. Elsevier Ltd.
Antigen receptor gene rearrangements are frequently applied as molecular targets for detection of minimal residual disease (MRD) in B-cell precursor acute lymphoblastic leukemia patients. Since such targets may be lost at relapse, appropriate selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa68493f1cc8d8776623a42f470605c1
https://pure.eur.nl/en/publications/a8ed3d8d-795b-4771-b466-7bdc844f2765
https://pure.eur.nl/en/publications/a8ed3d8d-795b-4771-b466-7bdc844f2765
Autor:
Andrew P. Stubbs, Mirjam van der Burg, Dik C. van Gent, Turkan Patiroglu, Jacob Rozmus, Robert A. Holt, Jacques J.M. van Dongen, Klaus Schwarz, Ingrid Pico-Knijnenburg, Erik J. Simons, H. Haluk Akar, Ricardo Leite, Myriam Ricarda Lorenz, David van Zessen, René L. Warren, Isabel S. Jerchel, Hanna IJspeert, Nicole S. Verkaik, Angela Wawer
Publikováno v:
Blood, 128(5), 650-659. American Society of Hematology
Repair of DNA double-strand breaks (DSBs) by the nonhomologous end-joining pathway (NHEJ) is important not only for repair of spontaneous breaks but also for breaks induced in developing lymphocytes during V(D)J (variable [V], diversity [D], and join
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7abaa5d07c6364e3fac57a280901fc
https://doi.org/10.1182/blood-2016-02-701029
https://doi.org/10.1182/blood-2016-02-701029