Evaluation of Commercially Available Viral Transport Medium (VTM) for SARS-CoV-2 Inactivation and Use in Point-of-Care (POC) Testing

Autor: David van Bockel, C. Mee Ling Munier, Stuart Turville, Steven G. Badman, Gregory Walker, Alberto Ospina Stella, Anupriya Aggarwal, Malinna Yeang, Anna Condylios, Anthony D. Kelleher, Tanya L. Applegate, Andrew Vallely, David Whiley, William Rawlinson, Phillip Cunningham, John Kaldor, Rebecca Guy

Publikováno v: Viruses, Vol 12, Iss 11, p 1208 (2020)

Critical to facilitating SARS-CoV-2 point-of-care (POC) testing is assurance that viruses present in specimens are inactivated onsite prior to processing. Here, we conducted experiments to determine the virucidal activity of commercially available Vi

Externí odkaz: https://doaj.org/article/0cdec5f61ca340978411048fb02003aa

The crossroads: divergent roles of virus‐specific CD4 + T lymphocytes in determining the outcome for human papillomavirus infection

Autor: David van Bockel, Anthony Kelleher

Publikováno v: Immunology & Cell Biology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55f4074aecf38c9231be75aaa2c634b1
https://doi.org/10.1111/imcb.12650

Navigating the complexity of chronic HIV-1 associated immune dysregulation

Autor: Mollie AA Boyd, David van Bockel, Cynthia Mee Ling Munier, Anthony D Kelleher

Publikováno v: Current opinion in immunology. 76

Despite successful viral suppression with antiretroviral therapy, chronic HIV-1 infection is associated with ongoing immune dysfunction. Investigation of the complex immune response in treated and untreated individuals with chronic HIV-1 infection is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89575378606b6dd554d49f4ee7ea4b72
https://pubmed.ncbi.nlm.nih.gov/35567953

Circulating gluten‐specific, but not CMV‐specific, CD39 + regulatory T cells have an oligoclonal TCR repertoire

Autor: Anthony D. Kelleher, David van Bockel, Jason A. Tye-Din, C Mee Ling Munier, Melinda Y Hardy, Robert P. Anderson, John Zaunders, Nabila Seddiki, Laura Cook

Publikováno v: Clinical & Translational Immunology, Vol 9, Iss 1, Pp n/a-n/a (2020)

Objectives Understanding the T cell receptor (TCR) repertoire of regulatory CD4+ T‐cell (Treg) populations is important for strategies aiming to re‐establish tolerance in autoimmune diseases. We studied circulating deamidated gluten‐epitope‐s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7017a67697810dfe1c4f4b7086c794fe
https://doi.org/10.1002/cti2.1096

HIV-1 DNA Is Maintained in Antigen-Specific CD4+ T Cell Subsets in Patients on Long-Term Antiretroviral Therapy Regardless of Recurrent Antigen Exposure

Autor: Andrew J. Leigh Brown, Robert Finlayson, Yin Xu, David van Bockel, Kersten K. Koelsch, William J. Hey-Nguyen, David A. Cooper, Michelle Bailey, Andrew Carr, Anthony D. Kelleher, Kazuo Suzuki, John Zaunders

Publikováno v: Hey-Nguyen, W, Bailey, M, Xu, Y, Suzuki, K, van Bockel, D, Finlayson, R, Leigh Brown, A, Carr, A, Cooper, D A, Kelleher, A D, Koelsch, K K & Zaunders, J 2019, ' HIV-1 DNA is Maintained in Antigen-Specific CD4+ T Cell Subsets in Patients on Long-Term Antiretroviral Therapy Regardless of Recurrent Antigen Exposure ', Aids research and human retroviruses, vol. 35, no. 1, pp. 112-120 . https://doi.org/10.1089/AID.2018.0235

Background: Memory CD4+ T cells (mCD4s) containing integrated HIV DNA are considered the main barrier to a cure for HIV infection. Here we analysed HIV DNA reservoirs in antigen-specific subsets of mCD4s to delineate the mechanisms by which HIV reser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25979b52b474994bffcc92467209aff6
https://pubmed.ncbi.nlm.nih.gov/30511878