Zobrazeno 1 - 10
of 56
pro vyhledávání: '"David Ziegler"'
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
Benedicte Grebstad Tune, Heena Sareen, Branka Powter, Smadar Kahana-Edwin, Adam Cooper, Eng-Siew Koh, Cheok S. Lee, Joseph W. Po, Geoff McCowage, Mark Dexter, Lucy Cain, Geraldine O’Neill, Victoria Prior, Jonathan Karpelowsky, Maria Tsoli, Lars O. Baumbusch, David Ziegler, Tara L. Roberts, Paul DeSouza, Therese M. Becker, Yafeng Ma
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2907 (2023)
Genetic histone variants have been implicated in cancer development and progression. Mutations affecting the histone 3 (H3) family, H3.1 (encoded by HIST1H3B and HIST1H3C) and H3.3 (encoded by H3F3A), are mainly associated with pediatric brain cancer
Externí odkaz:
https://doaj.org/article/444c9199ff6b4d05bfdb45dd6101a100
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178778 (2017)
Citizen science has become more popular in recent years, quickly taking on a variety of potentially conflicting characteristics: a way to collect massive data sets at relatively low cost, a way to break science out of the ivory tower and better engag
Externí odkaz:
https://doaj.org/article/9b28e15a8037483c90967800f6dac376
Autor:
Lauren Kelada, Eden Robertson, Skye McKay, Brittany McGill, Rebecca Daly, Carolyn Mazariego, Natalie Taylor, Elijah Tyedmers, Holly E. Evans, Claire Wakefield, David Ziegler
Background: Hard-to-treat childhood cancers are those where standard treatment options do not exist and prognosis is poor. Healthcare professionals (HCPs) are responsible for communicating with families about prognosis and complex experimental treatm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92cf200f1eaf8a52e84c68f65c2d07c4
https://doi.org/10.22541/au.168438965.52340962/v1
https://doi.org/10.22541/au.168438965.52340962/v1
Autor:
Allison L Bartlett, Adam Lane, Brooklyn Chaney, Nancy Yanez Escorza, Katie Black, Anne Cochrane, Jane Minturn, Ute Bartels, Kathy Warren, Jordan Hansford, David Ziegler, Blanca Diez, Stewart Goldman, Roger Packer, Mark Kieran, Mariko DeWire-Schottmiller, Craig Erker, Michelle Monje-Deisseroth, Lars Wagner, Carl Koschmann, Kathleen Dorris, Chie-Schin Shih, Tim Hassall, Yvan Samson, Paul Fisher, Stacie S Wang, Karen Tsui, Gustavo Sevlever, Xiaoting Zhu, Phillip Dexheimer, Anthony Asher, Christine Fuller, Rachid Drissi, Blaise Jones, James Leach, Maryam Fouladi
Publikováno v:
Neuro Oncol
Background Children ≤36 months with diffuse intrinsic pontine glioma (DIPG) have increased long-term survival (LTS, overall survival (OS) ≥24 months). Understanding distinguishing characteristics in this population is critical to improving outcom
Autor:
David Ziegler, Sebastian Wolff, Ana-Beatrice Agu, Giorgio Cortiana, Muhammad Umair, Flore de Durfort, Esther Neumann, Georg Walther, Jakob Kristiansen, Markus Lienkamp
Publikováno v:
Sustainability
Volume 15
Issue 4
Pages: 3203
Volume 15
Issue 4
Pages: 3203
Determining quantitative sustainable development metrics can be difficult and requires a high effort in manual data acquisition on an institutional level, like the Word Bank or the United Nations, without adequately reflecting reality. To overcome th
Publikováno v:
Evaluationsmethoden der Wissenschaftskommunikation ISBN: 9783658395810
ZusammenfassungWissenschaft und Kunst zu verbinden, zeichnet inzwischen viele Formate der Wissenschaftskommunikation aus. Wie Künstler:innen und Wissenschaftler:innen durch ihr Zusammenwirken wahrgenommen werden, wurde in der Evaluation des Wissensc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e0707b428798a48419c45dadc0331db
https://doi.org/10.1007/978-3-658-39582-7_8
https://doi.org/10.1007/978-3-658-39582-7_8
Autor:
Cornelis van Tilburg, David T Jones, Rene Schmidt, Shivaram Avula, Antoinette Schouten- van Meeteren, Astrid Sehested, Enrico Opocher, Pablo Hernáiz Driever, Ruth Witt, David Ziegler, Samuel Blackman, Xin Zhao, Li-Pen Tsao, Michael Cox, Darren Hargrave, Olaf Witt
Publikováno v:
Neuro-Oncology. 24:vii77-vii78
BACKGROUND Genomic alterations and dysregulation of RAF are the main oncogenic driver in almost all pediatric low-grade gliomas (pLGGs). About 50%‒60% of pLGGs harbor KIAA1549-BRAF fusion and 5%‒15% BRAF V600E mutation. No targeted therapy has re
Autor:
Elisha Hayden, Laura Franshaw, Dannielle Upton, Jie Liu, Hieu Nguyen, Swapna Joshi, Maria Tsoli, Emmy Dolman, Benjamin Rayner, David Ziegler
Publikováno v:
Cancer Research. 83:1561-1561
Diffuse Midline Gliomas (DMGs) are devastating and incurable pediatric brain tumours. DMGs are characterised by epigenetic aberrations in the form of histone modifications, coupled with mitotic abnormalities, which together drive a stem-like transcri
Autor:
Lindsay Kilburn, Daniel Landi, Sarah Leary, David Ziegler, Patricia Baxter, Andrea Franson, Geoffrey McCowage, Angela Waanders, Jasper Van der Lugt, Michal Yalon Oren, Nicolas Gerber, Nicholas Gottardo, Dong-Anh Khuong-Quang, Karsten Nysom, Simon Bailey, Pablo Hernáiz Driever, Sebastien Perreault, Olaf Witt, Seungmin Hahn, Darren Hargrave, Timothy Hassall, Nada Jabado, Hyoung Jin Kang, Valerie Larouche, Helen Toledano, Cassie Kline, Mohamed Abdelbaki, Susan Chi, Sharon Gardner, Nicholas Whipple, Sabine Mueller, Samuel Blackman, Xin Zhao, Daniel Da Costa, Michael Cox, Roger Packer, Jordan Hansford
Publikováno v:
Neuro-Oncology. 24:vii89-vii89
BACKGROUND RAF alterations are oncogenic drivers found in most pediatric low-grade gliomas (LGGs). Tovorafenib is an investigational, oral, selective, CNS-penetrant, small molecule, type II pan‑RAF inhibitor. METHODS FIREFLY-1 (NCT04775485) is a mu